Results 41 to 50 of about 1,942,616 (166)

An external validation study of a practical scoring system for identifying patients at risk of pelvic floor dysfunction following childbirth

open access: yesInternational Journal of Gynecology &Obstetrics, EarlyView.
Abstract Objective To prospectively evaluate the perineal card, a risk‐based scoring system, for identifying women at increased risk of postpartum urinary incontinence (UI). Methods This prospective observational study included women without previous vaginal delivery who underwent vaginal birth at a tertiary referral center between June 2023 and ...
Martina Arcieri   +14 more
wiley   +1 more source

The effects of thoracic epidurally administered drugs on urethral sphincter function in women: a pooled analysis [PDF]

open access: yes, 2013
OBJECTIVES: Thoracic epidural analgesia (TEA) has been shown to inhibit detrusor activity in patients undergoing open renal surgery, resulting in clinically relevant post-void residuals. However, the impact of different epidural drug mixtures on urethral
Kessler, Thomas M   +5 more
core   +1 more source

Transurethral versus suprapubic catheterization to test urethral function in rats

open access: yesScientific Reports, 2021
Transurethral and suprapubic catheterization have both been used to test urethral function in rats; however, it is unknown whether these methods affect urethral function or if the order of catheterization affects the results.
Kristine Janssen   +7 more
doaj   +1 more source

SPG4 Hereditary Spastic Paraplegia: From Etiology to Therapy

open access: yesMovement Disorders, EarlyView.
Abstract Hereditary spastic paraplegias (HSPs) comprise a heterogeneous group of heritable neurodegenerative disorders resulting from mutations in a wide variety of genes. HSP locomotor symptoms include lower limb weakness and spasticity that arise from progressive degeneration of corticospinal axons projecting from the motor cortex to the distal ...
Emanuela Piermarini, Peter W. Baas
wiley   +1 more source

Propagation of Pathological α-Synuclein from the Urogenital Tract to the Brain Initiates MSA-like Syndrome

open access: yesiScience, 2020
Summary: The neuropathological feature of multiple system atrophy (MSA), a fatal adult-onset disorder without effective therapy, is the accumulation of pathological α-synuclein (α-Syn) in the central nervous system (CNS). Here we show that pathological α-
Xuebing Ding   +12 more
doaj   +1 more source

Anatomy of Cowper’s gland in humans suggesting a secretion and emission mechanism facilitated by cooperation of striated and smooth muscles

open access: yesScientific Reports, 2021
This study presents the detailed anatomy of the Cowper’s gland in humans. Elucidating the mechanism of secretion and emission of the Cowper’s gland requires analysis of the muscles around the Cowper’s gland.
Satoru Muro   +2 more
doaj   +1 more source

How Can We Personalize the Delivery of Onabotulinumtoxin‐A for Patients With Neurogenic Lower Urinary Tract Dysfunction?

open access: yesNeurourology and Urodynamics, EarlyView.
ABSTRACT Background & Aims Neurogenic lower urinary tract dysfunction (NLUTD) can produce bothersome urinary symptoms, impact quality of life, and in some cases, lead to deterioration of upper urinary tract function. Intradetrusor injection of onabotulinumtoxin‐A (BoNT‐A) is approved for NLUTD in patients who have an inadequate response to or ...
Shirley L. Wang   +2 more
wiley   +1 more source

STEM CELLS IN THE TREATMENT OF URINARY STRESS INCONTINENCE – A VISION OF FUTURE?

open access: yesZdravniški Vestnik, 2018
Background. For one third of all women urinary incontinence is a health problem. Different strategies of treatment have been used, namely surgical, medical and physiotherapy. To this armamentarium a new method – adult stem cells therapy – has been added.
Adolf Lukanović
doaj   +1 more source

Advancing Personalized Care for Neurogenic Bladder: The Case for Continent Urinary Diversion

open access: yesNeurourology and Urodynamics, EarlyView.
ABSTRACT Introduction Neurogenic lower urinary tract dysfunction (NLUTD) with a poorly compliant bladder that is refractory to minimally invasive therapies (MIT) represents an “end‐stage” phenotype in which the principal objectives are durable upper urinary tract protection and restoration of continence with acceptable long‐term morbidity.
Francis A. Jefferson, Maude E. Carmel
wiley   +1 more source

Urodynamic Voiding Patterns in Multiple Sclerosis

open access: yesNeurourology and Urodynamics, EarlyView.
ABSTRACT Aims This study aimed to describe urodynamic voiding patterns in patients with MS (PwMS) using standardized assessments, and to compare the performance of the available nomograms and indices for obstruction and bladder contractility. Methods PwMS and lower urinary tract symptoms underwent cystometry and pressure flow studies.
Camille Chesnel   +5 more
wiley   +1 more source

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