Results 71 to 80 of about 1,942,616 (166)

Update on cellular expression and function of ANO1 channels in urethral smooth muscle

open access: yesThe Journal of Physiology, EarlyView.
Abstract figure legend Activation of ANO1 channels and resulting Cl− efflux are suggested to modulate urethral smooth muscle contractility by enhancing Ca2+ influx via voltage‐dependent Ca2+ entry and resulting contraction in urethral smooth muscle cells.
Bernard T. Drumm, Neha Gupta
wiley   +1 more source

Modeling Catheter‐Associated Bladder Mucosal Adhesion and Microtrauma Using a Human Urothelial Microtissue Model

open access: yesAdvanced NanoBiomed Research, Volume 6, Issue 10, October 2026.
Intermittent catheter use can damage the urinary tract and predispose to infection. We deployed a complex human urothelial model to investigate. Catheter contact induced compressive and shear stress causing umbrella cell disruption, reduced barrier function, inflammation and increased cell adhesion to the catheter surface.
Nazila V. Jafari, Jennifer L. Rohn
wiley   +1 more source

DRUG THERAPY OF NEUROGENIC BLADDER - THE EFFECTS OF ADMINISTRATION OF TOLPERISONE HYDROCHLORIDE TO PATIENTS WITH DYSSYNERGIA BETWEEN DETRUSOR AND EXTERNAL URETHRAL SPHINCTER - [PDF]

open access: yes, 1975
There are many patients with neurogenic bladder who complain of dyssynergia between detrusor and external urethral sphincter. Intra-abdominal pressure.
福井, 準之助
core  

Autonomic Plexuses of the Female Sexual Organs Travel Within Pubocervical and Rectovaginal [Endopelvic] Fascia: A Rationale for ‘Nerve‐Aware’ Vaginal Prolapse Repair

open access: yesClinical Anatomy, Volume 39, Issue 6, Page 672-682, September 2026.
ABSTRACT The connective tissue support of female pelvic viscera—endopelvic fascia—has been studied in fetal and immunohistochemical models to demonstrate its relationship with the autonomic nerves of the female pelvis. Due to a paucity of literature examining the gross anatomical relationships between endopelvic fascia and autonomic nerves in adult ...
Stephen Magliocchetti   +5 more
wiley   +1 more source

Brainstem control of urethral sphincter relaxation and scent marking behavior

open access: yes, 2018
Urination may occur either reflexively in response to a full bladder or deliberately irrespective of immediate need. Voluntary control is desired because it ensures that waste is expelled when consciously desired and socially appropriate1,2.
Varoth Lilascharoen   +7 more
core   +1 more source

Botulinun A toxin urethral sphincter injection for neurogenic or nonneurogenic voiding dysfunction [PDF]

open access: yes, 2016
Voiding dysfunction due to detrusor underactivity or urethral sphincter dysfunction is a treatment challenge for urologists. Recently, urologists have used botulinum toxin A (BoNT-A) injection into the urethral sphincter to treat voiding dysfunction ...
Kuo, Hann-Chorng
core   +1 more source

Fowler's syndrome: a primary disorder of urethral sphincter relaxation [PDF]

open access: yes, 2018
Key content: Urinary retention is a relatively uncommon presentation in young women. Women with Fowler's syndrome are often found to have an abnormally elevated urethral pressure profile, increased urethral sphincter volume and characteristically ...
Fowler, CJ, Pakzad, M, Panicker, JN
core   +2 more sources

Plateau pattern of detrusor contraction: A surrogate indicator of presence of external sphincter dysfunction during micturitional phase of urodynamic study

open access: yesIndian Journal of Urology, 2016
Introduction: Dysfunctional voiding results from a disturbance in the coordination between sphincter relaxation and detrusor contraction. Video urodynamic studies with electromyography (EMG) are used for diagnosis but have limitations of availability and
Mayank Mohan Agarwal   +4 more
doaj   +1 more source

Altered Glutamate Receptor Function during Recovery of Bladder Detrusor-External Urethral Sphincter Coordination in a Rat Model of Spinal Cord Injury

open access: yes, 2020
Coordination of the bladder detrusor and the external urethral sphincter is a supraspinally controlled reflex that is essential for efficient micturition.
Victor Pikov, Jean R Wrathall
core  

Electrical Stimulation Of The Sacral Dorsal Gray Commissure Evokes Relaxation Of The External Urethral Sphincter In The Cat

open access: yes, 1998
Stimulation of the pontine micturition center (PMC) results in micturition, i.e. an immediate relaxation of the urethral sphincter and a contraction of the detrusor muscle of the bladder.
Bertil F.M Blok   +8 more
core   +1 more source

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