Results 51 to 60 of about 285,551 (368)

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

open access: yesFEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

An Active Externalism about Personality

open access: yesFilosofia Unisinos, 2023
People display recognizably characteristic behavioral patterns across time and situations, with a given degree of regularity. These patterns may justify the attribution of personality traits.
Federico Burdman
doaj   +1 more source

Methylation biomarkers can distinguish pleural mesothelioma from healthy pleura and other pleural pathologies

open access: yesMolecular Oncology, EarlyView.
We developed and validated a DNA methylation–based biomarker panel to distinguish pleural mesothelioma from other pleural conditions. Using the IMPRESS technology, we translated this panel into a clinically applicable assay. The resulting two classifier models demonstrated excellent performance, achieving high AUC values and strong diagnostic accuracy.
Janah Vandenhoeck   +12 more
wiley   +1 more source

Spread Mind and Causal Theories of Content [PDF]

open access: yesAvant, 2014
In this paper, I analyze a type of externalist enactivism defended by Riccardo Manzotti. Such radical versions of enactivism are gaining more attention, especially in cognitive science and cognitive robotics.
Krystyna Bielecka
doaj  

Extended minds and prime mental conditions: probing the parallels [PDF]

open access: yes, 2018
Two very different forms of externalism about mental states appear prima facie unrelated: Williamson’s (1995, 2000) claim that knowledge is a mental state, and Clark & Chalmers’ (1998) extended mind hypothesis.
Drayson, Zoe
core  

How can neuroscience contribute to moral philosophy, psychology and education based on Aristotelian virtue ethics? [PDF]

open access: yes, 2016
The present essay discusses the relationship between moral philosophy, psychology and education based on virtue ethics, contemporary neuroscience, and how neuroscientific methods can contribute to studies of moral virtue and character. First, the present
Han, Hyemin
core   +2 more sources

Detection of circulating tumor DNA in colorectal cancer patients using a methylation‐specific droplet digital PCR multiplex

open access: yesMolecular Oncology, EarlyView.
We developed a cost‐effective methylation‐specific droplet digital PCR multiplex assay containing tissue‐conserved and tumor‐specific methylation markers. The assay can detect circulating tumor DNA with high accuracy in patients with localized and metastatic colorectal cancer.
Luisa Matos do Canto   +8 more
wiley   +1 more source

Is De Dicto motivation manifestly a no-go?

open access: yesRivista Internazionale di Filosofia e Psicologia
The aim of this paper is to challenge Michael Smith’s influential “fetishism charge” against motivational externalism – the view that moral judgments motivate only in the presence of a distinct conative state.
Irene Bosco
doaj   +1 more source

Assensum in mente prophetae: William of Ockham and Walter Chatton on Prophecies

open access: yesAnaliza i Egzystencja, 2021
The subject of this article is the intertwining between Walter Chatton and William of Ockham’s theories about the cognitive nature of prophetic statements, a topic in the theological debate of the early 14th century.
Roberto Limonta, Riccardo Fedriga
doaj   +1 more source

Perspectives in educating molecular pathologists on liquid biopsy: Toward integrative, equitable, and decentralized precision oncology

open access: yesMolecular Oncology, EarlyView.
Liquid biopsy enables minimally invasive, real‐time molecular profiling through analysis of circulating biomarkers in biological fluids. This Perspective highlights the importance of training pathologists through integrative educational programs, such as the European Masters in Molecular Pathology, to ensure effective and equitable implementation of ...
Marius Ilié   +13 more
wiley   +1 more source

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