Results 141 to 150 of about 3,255,505 (313)

BioCNTs Mediated Delivery of Systemically Mobile Small RNAs via Leaf Spray to Control Both Tomato DNA and RNA Viruses

Advanced Science, EarlyView.
A carbon nanotube‐based biopesticide system (BioCNTs) enables efficient delivery and systemic movement of RNAi molecules to control major tomato viruses. By integrating shRNA and tRNA‐like structures (TLS) with BioCNTs, this green and scalable approach achieves long‐term silencing and high antiviral efficacy through simple foliar spraying.
Xuedong Liu, Xiaofei Liang, Zipeng Cai, Zheng Liu, Xuefeng Wang, Changyong Zhou, Mengji Cao, Sijia Liu   +7 more
wiley   +1 more source

Biological recycling theory: a cyclic network framework for evolutionary innovation and recovery

Frontiers in Ecology and Evolution
IntroductionLife’s macroevolutionary patterns—rapid post-extinction recoveries and bursts of novelty—are not fully explained by mutation and vertical descent alone.
Sameh Mesallum
doaj   +1 more source

Interactions of Antibody Drug Conjugate Anti‐Tubulin and Topoisomerase I Inhibitor Payloads with Radiotherapy to Potentiate Immunotherapy

Advanced Science, EarlyView.
Antibody drug conjugates deliver their cytotoxic anti‐tubulin or topoisomerase I inhibitor payloads to tumors through cancer cell receptor targeting. The released drug payloads induce cellular changes that interact with radiotherapy resulting in radiosensitization that improves cancer cell kill and stimulates anti‐tumor immune responses.
Jacqueline Lesperance, Bryan S. Yung, Michael M. Allevato, Marcus M Cheng, Maria F. Camargo, Robert Saddawi‐Konefka, Kanika Dhawan, Ashwyn K. Sharma, Mahsa Mortaja, Sophie Bice, Daniel J. Scanderbeg, Diego Alvarado, Jyoti Mayadev, Ramez N. Eskander, Stephen R. Adams, Pippa F. Cosper, J. Silvio Gutkind, Sunil J. Advani   +17 more
wiley   +1 more source

TBK1 Induces the Formation of Optineurin Filaments That Condensate with Polyubiquitin and LC3 for Cargo Sequestration

Advanced Science, EarlyView.
Phosphorylation of Optineurin by TBK1 induces the formation of filaments that condensate upon binding to linear polyubiquitin. Membrane‐anchored LC3 partitions into these condensates, suggesting that phase separation of filamentous Optineurin with ubiquitylated cargo promotes the sequestration of cargo and its subsequent alignment with LC3‐positive ...
Maria G. Herrera, Lena Kühn, Lisa Jungbluth, Verian Bader, Laura J. Krause, David Kartte, Elias Adriaenssens, Sascha Martens, Jörg Tatzelt, Carsten Sachse, Konstanze F. Winklhofer   +10 more
wiley   +1 more source

Dynamical and phenomenological bifurcations induced by multiplicative noise in a stochastic single-species model with double Allee effect

AIMS Mathematics
The interplay between system nonlinearity and environmental noise can lead to counterintuitive phenomena that deterministic models are unable to explain. However, the underlying mechanisms are not fully understood. In this study, we proposed a stochastic
Liang Hong, Yanhua Yang
doaj   +1 more source

The predictability of extinction: biological and external correlates of decline in mammals

Proceedings of the Royal Society B: Biological Sciences, 2008
M. Cardillo, G. Mace, J. L. Gittleman, Kate E. Jones, J. Bielby, A. Purvis   +5 more
semanticscholar   +1 more source

Balanced Expression of the Diiron Oxygenase BioE Is Essential for Biotin Homeostasis in Elizabethkingia meningoseptica

Advanced Science, EarlyView.
BioE is a new diiron oxygenase that catalyzes the conversion of long‐chain acyl groups into pimeloyl thioester, initiating biotin synthesis. The overexpression of EmBioE disrupts lipid metabolic homeostasis, requiring repressor BioL to maintain a balance between long‐chain fatty acids and biotin synthesis.
Meng Zhang, Ying‐ying Fu, Xiaoqiang Yang, Qiuying Qin, Xinyu Su, Jiaming Fang, Yanhua Kang, Qingwen He, Zhi Ruan, Yongchang Xu   +9 more
wiley   +1 more source

LA CONSERVACIÓN BIOLÓGICA Y SU PERSPECTIVA EVOLUTIVA

Acta Biológica Colombiana, 2009
RESUMEN Este artículo revisa dos de las principales causas de amenaza a la diversidad biológica, como son la fragmentación y/o pérdida del hábitat y la introducción e invasión de especies exóticas, principalmente en lo que compete a sus implicaciones ...
Olga Montenegro
doaj  

Decline in extinction rates and scale invariance in the fossil record

, 1998
We show that the decline in the extinction rate during the Phanerozoic can be accurately parameterized by a logarithmic fit to the cumulative total extinction. This implies that extinction intensity is falling off approximately as the reciprocal of time.
Eble, Gunther J., Newman, M. E. J.
core   +2 more sources

Biological extinction at the Vatican [PDF]

Nature Ecology & Evolution, 2017
openaire   +2 more sources