Results 1 to 10 of about 3,063,933 (183)

Extracellular Proteome Analysis Shows the Abundance of Histidine Kinase Sensor Protein, DNA Helicase, Putative Lipoprotein Containing Peptidase M75 Domain and Peptidase C39 Domain Protein in Leptospira interrogans Grown in EMJH Medium

Pathogens, 2021
Leptospirosis is a re-emerging form of zoonosis that is caused by the spirochete pathogen Leptospira. Extracellular proteins play critical roles in the pathogenicity and survival of this pathogen in the host and environment.
Abhijit Sarma, Dhandapani Gunasekaran, Devasahayam Arokia Balaya Rex, Thoduvayil Sikha, Homen Phukan, Kumar Mangalaparthi Kiran, Sneha M. Pinto, Thottethodi Subrahmanya Keshava Prasad, Madathiparambil G. Madanan   +8 more
doaj   +1 more source

A Triple High Throughput Screening for Extracellular Vesicle Inducing Agents With Immunostimulatory Activity

Frontiers in Pharmacology, 2022
Extracellular vesicles (EVs) play an important role in intercellular communication and regulation of cells, especially in the immune system where EVs can participate in antigen presentation and may have adjuvant effects.
Nikunj M. Shukla, Fumi Sato-Kaneko, Shiyin Yao, Minya Pu, Michael Chan, Fitzgerald S. Lao, Yukiya Sako, Tetsuya Saito, Tetsuya Saito, Karen Messer, Tomoko Hayashi, Howard B. Cottam, Maripat Corr, Dennis A. Carson   +13 more
doaj   +1 more source

Targeting extracellular Hsp90: A unique frontier against cancer

Frontiers in Molecular Biosciences, 2022
The molecular chaperone Heat Shock Protein-90 (Hsp90) is known to interact with over 300 client proteins as well as regulatory factors (eg. nucleotide and proteins) that facilitate execution of its role as a chaperone and, ultimately, client protein ...
Rebecca A. Sager, Rebecca A. Sager, Farzana Khan, Farzana Khan, Lorenzo Toneatto, Lorenzo Toneatto, Lorenzo Toneatto, SarahBeth D. Votra, Sarah J. Backe, Sarah J. Backe, Sarah J. Backe, Mark R. Woodford, Mark R. Woodford, Mark R. Woodford, Mehdi Mollapour, Mehdi Mollapour, Mehdi Mollapour, Dimitra Bourboulia, Dimitra Bourboulia, Dimitra Bourboulia   +19 more
doaj   +1 more source

Identification of a novel zinc metalloprotease through a global analysis of clostridium difficile extracellular proteins [PDF]

, 2013
Clostridium difficile is a major cause of infectious diarrhea worldwide. Although the cell surface proteins are recognized to be important in clostridial pathogenesis, biological functions of only a few are known.
A Barketi-Klai, A Bateman, A Boetzkes, A Dhalluin, A Molla, A Tasteyre, A Tasteyre, A Tasteyre, A Wright, A Wright, AJ Waligora, B Singh, BR Hoffmann, C Janoir, C Schwan, CB Reynolds, CC Häse, CM Surawicz, D Lyras, D Zhang, Davide Serruto, DC Nelson, DE Voth, DJ Rigden, E Calabi, E Calabi, EJ Kuipers, F Tonello, FH Niesen, Francesca Cantini, G Bensi, GA Dalkas, GM Slynn, H Maeda, I Poilane, Jeffrey T. Rubino, JM Kirby, JR O'Connor, JW Teo, K Mukherjee, K Yokoyama, KR Klimpel, L de la Riva, L Tulli, LG Pacheco, M Cerquetti, M Desvaux, M Miura, M Monot, M Rupnik, M Sebaihia, M Warny, MA Breidenbach, Manuele Martinelli, Maria Scarselli, Massimiliano Biagini, Meera Unnikrishnan, Mikael Skurnik, MJ Rodríguez-Ortega, N Sengupta, Nathalie Norais, NM Hooper, NS Duesbery, O Schneewind, Rosanna Leuzzi, RP Fagan, S Péchiné, S Péchiné, S Ravipaty, SA Kuehne, T Karasawa, T Karjalainen, TC Dingle, Valeria Cafardi   +73 more
core   +11 more sources

The Role of Extracellular Vesicles in Osteoporosis: A Scoping Review

Membranes, 2022
As an insidious metabolic bone disease, osteoporosis plagues the world, with high incidence rates. Patients with osteoporosis are prone to falls and becoming disabled, and their cone fractures and hip fractures are very serious, so the diagnosis and ...
Weifei Zhang, Pengzhou Huang, Jianjing Lin, Hui Zeng   +3 more
doaj   +1 more source

Reduction in Glomerular and Renal Tubular Damage in Kidneys of Diabetic Rats Supplemented with Alpha-Lipoic Acid

Acta Veterinaria, 2022
Chronic hyperglycemia caused by diabetes results in systemic damage to the body, and the kidney ends up being the target of tissue damage. The use of antioxidants such as alpha-lipoic acid (ALA) has been shown to improve clinical and biochemical ...
Fraga Tamyris Pontes, Corrêa Lanna Beatriz Neves Silva, Taboas Julia Galian Ribeiro, Da Silva Vivian Alves Pereira, Boaventura Gilson Teles, Chagas Mauricio Alves   +5 more
doaj   +1 more source

Extracellular Vesicles in neural cell interaction and CNS homeostasis

FASEB BioAdvances, 2021
Central nervous system (CNS) homeostasis critically depends on the interaction between neurons and glia cells. Extracellular vesicles (EVs) recently emerged as versatile messengers in CNS cell communication.
Andrea Schnatz, Christina Müller, Alexandra Brahmer, Eva‐Maria Krämer‐Albers   +3 more
doaj   +1 more source

The root pathogen Aphanomyces euteiches secretes modular proteases in pea apoplast during host infection

Frontiers in Plant Science, 2023
To successfully colonize the host, phytopathogens have developed a large repertoire of components to both combat the host plant defense mechanisms and to survive in adverse environmental conditions.
Andrei Kiselev, Laurent Camborde, Laura Ossorio Carballo, Farnusch Kaschani, Markus Kaiser, Renier A. L. van der Hoorn, Elodie Gaulin   +6 more
doaj   +1 more source

An Investigation of The Effect of Extracellular Vesicles Isolated from Mouse Embryonic Fibroblasts on Wound Healing in an Experimental Diabetic Mouse Model

Anais da Academia Brasileira de Ciências, 2022
This study aimed to investigate the effects of Extracellular Vesicles (EV) secreted from mouse embryonic fibroblasts EV on wound healing of full-thickness skin defect in a diabetic mouse model.
AHMET S. BOZKURT, DAVUT S. KAPLAN, ALI O. ÇERİBAŞI, MUSTAFA ORKMEZ, ASUMAN ÇANAK, MEHMET TARAKÇIOĞLU   +5 more
doaj   +1 more source

Microencapsulation technology by nature: Cell derived extracellular vesicles with therapeutic potential [PDF]

, 2013
Cell derived extracellular vesicles are submicron structures surrounded by phospholipid bilayer and released by both prokaryotic and eukaryotic cells.
Buzás, E., Falus, A., Kittel, Ágnes
core   +1 more source