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Extracellular Vesicles in neural cell interaction and CNS homeostasis

open access: yesFASEB BioAdvances, 2021
Central nervous system (CNS) homeostasis critically depends on the interaction between neurons and glia cells. Extracellular vesicles (EVs) recently emerged as versatile messengers in CNS cell communication.
Andrea Schnatz   +3 more
doaj   +1 more source

Reduction in Glomerular and Renal Tubular Damage in Kidneys of Diabetic Rats Supplemented with Alpha-Lipoic Acid

open access: yesActa Veterinaria, 2022
Chronic hyperglycemia caused by diabetes results in systemic damage to the body, and the kidney ends up being the target of tissue damage. The use of antioxidants such as alpha-lipoic acid (ALA) has been shown to improve clinical and biochemical ...
Fraga Tamyris Pontes   +5 more
doaj   +1 more source

Targeting extracellular Hsp90: A unique frontier against cancer

open access: yesFrontiers in Molecular Biosciences, 2022
The molecular chaperone Heat Shock Protein-90 (Hsp90) is known to interact with over 300 client proteins as well as regulatory factors (eg. nucleotide and proteins) that facilitate execution of its role as a chaperone and, ultimately, client protein ...
Rebecca A. Sager   +19 more
doaj   +1 more source

A Triple High Throughput Screening for Extracellular Vesicle Inducing Agents With Immunostimulatory Activity

open access: yesFrontiers in Pharmacology, 2022
Extracellular vesicles (EVs) play an important role in intercellular communication and regulation of cells, especially in the immune system where EVs can participate in antigen presentation and may have adjuvant effects.
Nikunj M. Shukla   +13 more
doaj   +1 more source

Investigating the consistency of extracellular vesicle production from breast cancer subtypes using CELLine adherent bioreactors

open access: yesJournal of Extracellular Biology, 2022
Extracellular vesicle (EV) research has grown rapidly in recent years, largely due to the potential use of EVs as liquid biopsy biomarkers or therapeutics.
Colin L. Hisey   +8 more
doaj   +1 more source

The Role of Extracellular Vesicles in Osteoporosis: A Scoping Review

open access: yesMembranes, 2022
As an insidious metabolic bone disease, osteoporosis plagues the world, with high incidence rates. Patients with osteoporosis are prone to falls and becoming disabled, and their cone fractures and hip fractures are very serious, so the diagnosis and ...
Weifei Zhang   +3 more
doaj   +1 more source

Extracellular Proteome Analysis Shows the Abundance of Histidine Kinase Sensor Protein, DNA Helicase, Putative Lipoprotein Containing Peptidase M75 Domain and Peptidase C39 Domain Protein in Leptospira interrogans Grown in EMJH Medium

open access: yesPathogens, 2021
Leptospirosis is a re-emerging form of zoonosis that is caused by the spirochete pathogen Leptospira. Extracellular proteins play critical roles in the pathogenicity and survival of this pathogen in the host and environment.
Abhijit Sarma   +8 more
doaj   +1 more source

An Investigation of The Effect of Extracellular Vesicles Isolated from Mouse Embryonic Fibroblasts on Wound Healing in an Experimental Diabetic Mouse Model

open access: yesAnais da Academia Brasileira de Ciências, 2022
This study aimed to investigate the effects of Extracellular Vesicles (EV) secreted from mouse embryonic fibroblasts EV on wound healing of full-thickness skin defect in a diabetic mouse model.
AHMET S. BOZKURT   +5 more
doaj   +1 more source

Characterization of the B-Cell Epitopes of Echinococcus granulosus Histones H4 and H2A Recognized by Sera From Patients With Liver Cysts

open access: yesFrontiers in Cellular and Infection Microbiology, 2022
Cystic echinococcosis (CE) is a zoonotic disease worldwide distributed, caused by the cestode Echinococcus granulosus sensu lato (E. granulosus), with an incidence rate of 50/100,000 person/year and a high prevalence in humans of 5-10%.
Andrea Maglioco   +8 more
doaj   +1 more source

Minimal information for studies of extracellular vesicles 2018 (MISEV2018): a position statement of the International Society for Extracellular Vesicles and update of the MISEV2014 guidelines

open access: yesJournal of Extracellular Vesicles, 2018
The last decade has seen a sharp increase in the number of scientific publications describing physiological and pathological functions of extracellular vesicles (EVs), a collective term covering various subtypes of cell-released, membranous structures ...
C. Théry   +381 more
semanticscholar   +1 more source

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