Results 131 to 140 of about 2,129,035 (302)

Molecular insights into the unique properties of the blood‐circulating proteasome

Journal of Extracellular Biology
Proteasomes are essential for protein degradation and maintaining cellular balance, yet their roles in extracellular fluids are not well understood.
Yegor Leushkin, David Morgenstern, Shifra Ben‐Dor, Rebecca Haffner‐Krausz, Katharina Zittlau, Gili Ben‐Nissan, Michal Sharon   +6 more
doaj   +1 more source

Profiling neoadjuvant therapy response in rectal cancer using meta‐analysis of publicly available transcriptomic RNA‐seq datasets

Molecular Oncology, EarlyView.
This study integrates publicly available transcriptomic datasets to identify molecular signatures associated with response to neoadjuvant chemoradiotherapy in locally advanced rectal cancer. By analyzing a combination of multiple cohorts with bioinformatics approaches, we reveal biological pathways and immune‐related features that may improve ...
Aleksandra Stanojevic, Rafael Stroggilos, Mladen Marinkovic, Ana Djuric, Suzana Stojanovic‐Rundic, Radmila Jankovic, Sergi Castellvi‐Bel, Remond J.A. Fijneman, Antonia Vlahou, Jerome Zoidakis, Milena Cavic   +10 more
wiley   +1 more source

The VHL tumor suppressor at the crossroad of protein folding, aggregation, and cancer

Molecular Oncology, EarlyView.
Mutations, environmental stress, and chaperone dysfunction can destabilize pVHL, promoting its conversion from the native folded state into amyloid‐like assemblies. This transition may contribute to protein storage, cell dormancy, survival, and drug resistance.
Lara Abad, Silvio Carlo Ermanno Tosatto, Emanuela Leonardi   +2 more
wiley   +1 more source

The Ability for the Extracellular Production of Iron Oxide Nanoparticles by Klebsiella pneumoniae and Staphylococcus aureus

Medical Journal of Babylon
Background: The biological production of nanoparticles is emerging as a possible method for nanoparticle synthesis due to its simplicity and lack of toxicity.
Diana Faisal Ali Rasheed, Hiro Mohammed Obaid   +1 more
doaj   +1 more source

Cardiac extracellular matrix: a dynamic entity

, 2005
Understanding the regulation of the extracellular matrix of the heart is essential to understanding the chronic changes in heart function in disease states such as hypertension, heart failure, and diabetes.
Brown, Lindsay, Brown, L
core   +1 more source

Extracellular vesicle lipidomics liquid biopsy reveals systemic and tumor microenvironment metabolic reprogramming in ovarian cancer

Molecular Oncology, EarlyView.
Extracellular vesicle (EV) lipidomic profiling of plasma and ascites from patients with high‐grade serous ovarian cancer and of ovarian cancer cell lines reveals enrichment of triglycerides (TGs), diacylglycerols (DGs), phosphatidylcholine (PCs), sphingomyelins (SMs), reflecting tumor metabolic reprogramming.
Shikha Rani, Dominic Guanzon, Andrew Lai, Katherin Scholz‐Romero, Sarah Reed, Edita Ritmejeryte, Rohan Lourie, Naven Chetty, Kaltin Ferguson, Carlos Salomon   +9 more
wiley   +1 more source

Isolation and characterization of a novel highly efficient bacterium Lysinibacillus boronitolerans QD4 for quantum dot biosynthesis

Frontiers in Microbiology
Microorganism-based biosynthesis of quantum dots is a low-cost and green production method with a wide range of potential applications. The development of environmentally friendly synthesis methods is required due to the toxicity and severe reactions ...
Xingyu Gu, Xingyu Gu, Xiaoju Li, Ruijia Zhang, Ruijia Zhang, Ruoli Zheng, Ruoli Zheng, Mingrui Li, Mingrui Li, Rong Huang, Xin Pang   +10 more
doaj   +1 more source

Predictive and prognostic biomarkers of Bacillus Calmette‐Guérin therapy failure in bladder cancer patients: A systematic review

Molecular Oncology, EarlyView.
High‐risk bladder cancer is typically treated with Bacillus Calmette‐Guérin (BCG), but 30–40% of patients relapse. No FDA‐ or CE‐approved biomarkers currently predict or prognosticate BCG failure. We systematically reviewed the literature and identified 72 eligible studies, revealing several promising biomarkers associated with BCG treatment response ...
Rui Ribeiro‐Pereira, Ana Teixeira‐Marques, Rui Freitas, João A Carvalho, Sara Monteiro‐Reis, Giorgio I. Russo, Rui Henrique, Carmen Jerónimo   +7 more
wiley   +1 more source

A Mean Field Poisson–Boltzmann Theory Assessment of Copper Oxide Nanosheets Interaction Potential in Physiological Fluids

Nanomaterials
In recent times, copper oxide nanosheets (CONSs) have shown a broad spectrum of industrial uses due to their unique properties, including high electrical conductivity, surface-enhanced catalytic activity, etc.
Mumuni Amadu, Nafisat Motunrayo Raheem, Adango Miadonye   +2 more
doaj   +1 more source

The extracellular lysosome [PDF]

Arthritis & Rheumatism, 1981
openaire   +2 more sources