Results 191 to 200 of about 1,944,890 (372)

ShcD adaptor protein drives invasion of triple negative breast cancer cells by aberrant activation of EGFR signaling

open access: yesMolecular Oncology, EarlyView.
We identified adaptor protein ShcD as upregulated in triple‐negative breast cancer and found its expression to be correlated with reduced patient survival and increased invasion in cell models. Using a proteomic screen, we identified novel ShcD binding partners involved in EGFR signaling pathways.
Hayley R. Lau   +11 more
wiley   +1 more source

An innovative in silico model of the oral mucosa reveals the impact of extracellular spaces on chemical permeation through epithelium [PDF]

open access: yesarXiv
In pharmaceutical therapeutic design or toxicology, accurately predicting the permeation of chemicals through human epithelial tissues is crucial, where permeation is significantly influenced by the tissue's cellular architecture. Current mathematical models for multi-layered epithelium such as the oral mucosa only use simplistic 'bricks and mortar ...
arxiv  

DETERMINATION OF THE VOLUME OF THE EXTRACELLULAR FLUID OF THE BODY WITH RADIOACTIVE SODIUM [PDF]

open access: bronze, 1941
Nolan L. Kaltreider   +3 more
openalex   +1 more source

Time, the final frontier

open access: yesMolecular Oncology, EarlyView.
This article advocates integrating temporal dynamics into cancer research. Rather than relying on static snapshots, researchers should increasingly consider adopting dynamic methods—such as live imaging, temporal omics, and liquid biopsies—to track how tumors evolve over time.
Gautier Follain   +3 more
wiley   +1 more source

INTRACELLULAR AND EXTRACELLULAR POTASSIUM DEFICITS IN SURGICAL PATIENTS

open access: green, 1952
Robert Elman   +3 more
openalex   +2 more sources

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