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Biogenesis, secretion, and intercellular interactions of exosomes and other extracellular vesicles.
Annual Review of Cell and Developmental Biology, 2014In the 1980s, exosomes were described as vesicles of endosomal origin secreted from reticulocytes. Interest increased around these extracellular vesicles, as they appeared to participate in several cellular processes.
Marina Colombo, G. Raposo, C. Théry
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Neutrophil Extracellular Traps Kill Bacteria
Science, 2004Neutrophils engulf and kill bacteria when their antimicrobial granules fuse with the phagosome. Here, we describe that, upon activation, neutrophils release granule proteins and chromatin that together form extracellular fibers that bind Gram-positive ...
V. Brinkmann+7 more
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A guide to the composition and functions of the extracellular matrix
The FEBS Journal, 2021Extracellular matrix (ECM) is a dynamic 3‐dimensional network of macromolecules that provides structural support for the cells and tissues. Accumulated knowledge clearly demonstrated over the last decade that ECM plays key regulatory roles since it ...
Nikos Karamanos+16 more
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Extracellular Calcium Sensing and Extracellular Calcium Signaling
Physiological Reviews, 2001The cloning of a G protein-coupled extracellular Ca2+(Cao2+)-sensing receptor (CaR) has elucidated the molecular basis for many of the previously recognized effects of Cao2+on tissues that maintain systemic Cao2+homeostasis, especially parathyroid chief cells and several cells in the kidney. The availability of the cloned CaR enabled the development of
R. John MacLeod, Edward M. Brown
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The International Journal of Artificial Organs, 2011
Extracellular DNA (eDNA) is an important biofilm component that was recently discovered. Its presence has been initially observed in biofilms of Pseudomonas aeruginosa, Streptococcus intermedius, Streptococcus mutans, then Enterococcus faecalis and staphylococci. Autolysis is the common mechanism by which eDNA is released. In P.
MONTANARO, LUCIO+6 more
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Extracellular DNA (eDNA) is an important biofilm component that was recently discovered. Its presence has been initially observed in biofilms of Pseudomonas aeruginosa, Streptococcus intermedius, Streptococcus mutans, then Enterococcus faecalis and staphylococci. Autolysis is the common mechanism by which eDNA is released. In P.
MONTANARO, LUCIO+6 more
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The role of extracellular DNA in neutrophil extracellular traps [PDF]
Pseudomonas aeruginosa is an opportunistic pathogen and the primary pathogen in lung infections in patients with Cystic Fibrosis (CF). Neutrophils are recruited to the site of infection to clear the invading bacteria by phagocytosis and neutrophil extracellular trap (NET) formation.
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2010
Publisher Summary Extracellular matrix is a dynamic organelle that surrounds the cell. It is a matrix of polysaccharide and protein polymers that prevents cell lysis and allows the development of a hydrostatic pressure within the cell that provides mechanical support for the plant. In general, the plant extracellular matrix is approximately 60 percent
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Publisher Summary Extracellular matrix is a dynamic organelle that surrounds the cell. It is a matrix of polysaccharide and protein polymers that prevents cell lysis and allows the development of a hydrostatic pressure within the cell that provides mechanical support for the plant. In general, the plant extracellular matrix is approximately 60 percent
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Cell–extracellular matrix mechanotransduction in 3D
Nature reviews. Molecular cell biology, 2023Aashrith Saraswathibhatla+2 more
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