Extracellular HSPs: The Complicated Roles of Extracellular HSPs in Immunity [PDF]
Frontiers in Immunology, 2016 Extracellular heat-shock proteins (HSPs) interact with the immune system in a very complex manner. Many such HSPs exert powerful effects on the immune response, playing both stimulatory and regulatory roles. However, the influence of the HSPs on immunity appears to be positive or negative in nature - rarely neutral.
Calderwood, Stuart K. +2 more
openaire +5 more sources
Non-Coding RNA, 2019 MicroRNAs play functional roles in the etiology of type 2 diabetes mellitus (T2DM) and complications, and extracellular microRNAs have attracted interest as potential biomarkers of these conditions.
Ari Meerson +5 more
doaj +1 more source
Anais da Academia Brasileira de Ciências, 2022 This study aimed to investigate the effects of Extracellular Vesicles (EV) secreted from mouse embryonic fibroblasts EV on wound healing of full-thickness skin defect in a diabetic mouse model.
AHMET S. BOZKURT +5 more
doaj +1 more source
Extracellular signal-regulated kinases mediate the enhancing effects of inflammatory mediators on resurgent currents in dorsal root ganglion neurons [PDF]
, 2019 Previously we reported that a group of inflammatory mediators significantly enhanced resurgent currents in dorsal root ganglion neurons. To understand the underlying intracellular signaling mechanism, we investigated the effects of inhibition of ...
Cummins, Theodore R. +6 more
core +1 more source
Frontiers in Cellular and Infection Microbiology, 2022 Cystic echinococcosis (CE) is a zoonotic disease worldwide distributed, caused by the cestode Echinococcus granulosus sensu lato (E. granulosus), with an incidence rate of 50/100,000 person/year and a high prevalence in humans of 5-10%.
Andrea Maglioco +8 more
doaj +1 more source
mGluR5 antagonism inhibits cocaine reinforcement and relapse by elevation of extracellular glutamate in the nucleus accumbens via a CB1 receptor mechanism. [PDF]
, 2018 Metabotropic glutamate receptor 5 (mGluR5) antagonism inhibits cocaine self-administration and reinstatement of drug-seeking behavior. However, the cellular and molecular mechanisms underlying this action are poorly understood.
Bi, Guo-Hua +9 more
core +2 more sources
Extracellular calcium reduction strongly increases the lytic capacity of pneumolysin from streptococcus pneumoniae in brain tissue [PDF]
, 2011 Background. Streptococcus pneumoniae causes serious diseases such as pneumonia and meningitis. Its major pathogenic factor is the cholesterol-dependent cytolysin pneumolysin, which produces lytic pores at high concentrations.
Asparouh I. Iliev +40 more
core +3 more sources
Hayati Journal of Biosciences, 2008 Penicillin G acylase (PGA) which catalyses penicillin G hydrolysis reaction is a key enzyme for the industrial production of penicilin G derivatives used in therapeutics.
SUPARTONO +3 more
doaj +3 more sources
Intracellular impedance measurements reveal non-ohmic properties of the extracellular medium around neurons [PDF]
Biophysical Journal 110: 234-246, 2016, 2015 The electrical properties of extracellular space around neurons are important to understand the genesis of extracellular potentials, as well as for localizing neuronal activity from extracellular recordings. However, the exact nature of these extracellular properties is still uncertain.
arxiv +1 more source
Exploring the biochemistry at the extracellular redox frontier of bacterial mineral Fe(III) respiration [PDF]
, 2012 Many species of the bacterial Shewanella genus are notable for their ability to respire in anoxic environments utilizing insoluble minerals of Fe(III) and Mn(IV) as extracellular electron acceptors.
Andrew J. Gates +27 more
core +3 more sources