Results 121 to 130 of about 1,499,817 (257)
Accurate and noninvasive prostate cancer detection using plasma‐derived extracellular vesicle RNA
FEBS Open Bio, EarlyView.Plasma extracellular vesicles were captured with WGA‐conjugated magnetic beads and profiled for RNA biomarkers. A three‐RNA panel (NM_024955, NR_047469, and NR_002564) distinguished prostate cancer from healthy controls and benign prostatic hyperplasia, supporting a simple, noninvasive approach to improve prostate cancer detection.
Hanping Wei, Haoran Wu, Wei Feng
wiley +1 more source
Protocol for quantifying miRNA trafficking across the endosomal membrane
FEBS Open Bio, EarlyView.An in vitro protocol measures miRNA uptake into endosomes isolated from mammalian cell extracts, which are free of subcellular contaminants. Performed at 37 °C in the presence of ATP, it ensures the import of single‐stranded miRNA into the endosomal lumen.
Syamantak Ghosh +2 more
wiley +1 more source
FEBS Open Bio, EarlyView.The neurokinin 1 receptor exists as full‐length (NK1L) and C‐terminally truncated (NK1S) splice variants. We show that NK1S heterodimerizes with NK1L, impairing Gαq coupling and Ca2+ mobilization while enhancing β‐arrestin1 recruitment. NK1S suppresses substance P‐driven gene expression and cell migration, revealing NK1S as an endogenous biased ...
Lan Phuong Nguyen +8 more
wiley +1 more source
The data set (lab data, code,...) regarding my paper about enzyme kinetics in a sandy agricultural soil, amended with both biochar and basanite. Paper title: Biochar dominated the combined effect of silicate rock powder and biochar application on ...
Maria Ansari
core +1 more source
, 2016 Results from ANOVA testing the effects of climate-change treatments on extracellular enzyme activities in plant community soils and in plant-specific ...
Courtney E. Campany (360787) +3 more
core +1 more source
Effect of Exogenic Proteolytic Enzymes on Transfer of Plasmid Genes in Mixed Bacterial Biofilms
Антибиотики и Химиотерапия, 2020 The effect of the enzyme complex from Vobenzin on transfer of plasmid genes In biofilms of gramnegative bacteria was studied. The extracellular matrix of the bacterial biofilms was shown to contain extracellular DNA carrying the antibiotic resistance ...
G. V. Tets +6 more
doaj
Selective elimination of quiescent cancer cells by dequalinium chloride via ROS‐mediated ferroptosis
FEBS Open Bio, EarlyView.Dequalinium chloride (DQ) selectively eliminates quiescent cancer cells (QCCs) by amplifying mitochondrial ROS. QCCs exhibit elevated basal ROS and limited redox‐buffering capacity, making them vulnerable to further ROS increases. DQ‐induced ROS exceeds the tolerance threshold, triggering lipid peroxidation and ferroptosis, whereas proliferating cells ...
Kotaro Miyamoto +14 more
wiley +1 more source
, 2016 Extracellular enzyme activities on substrates harvested during the first three years of the experiment by substrate (averaged over sites and treatments)
William C. Eddy (2933169) +5 more
core +1 more source
Enzyme Immobilization on Polysaccharides for Biofilm Degradation in Tissue Constructs
Journal of Pure and Applied MicrobiologyThe surfaces of medical devices can quietly become breeding grounds for resilient bacterial colonies, which pose a significant risk to patients. These microorganisms form complex communities embedded within a self-produced extracellular matrix known as ...
Saranya Mutsuddi +2 more
doaj +1 more source
Characterization of the key membrane protein cytochrome Cyc2 from Ghiorsea bivora
FEBS Open Bio, EarlyView.This study reports the first detailed biochemical analysis of Cyc2TAG1_1, a cytochrome protein involved in microbial iron oxidation. We produced and purified this enzyme in E. coli, then measured its iron‐oxidizing efficiency, and characterized its electrical and structural properties.
Josiane Azizi +6 more
wiley +1 more source