Results 41 to 50 of about 1,434,762 (289)

Decoding the dynamic extracellular matrix in cancer—3D models and bioscaffolds rewire the rules of tumor progression

open access: yesFEBS Letters, EarlyView.
Cancer progression is regulated by the dynamic matrix code of the tumor microenvironment, which influences cellular behavior and disease development. Importantly, matrix remodeling in three‐dimensional cancer models more accurately reflects in vivo conditions compared to conventional two‐dimensional systems.
Sylvia Mangani   +3 more
wiley   +1 more source

Minimal information for studies of extracellular vesicles 2018 (MISEV2018): a position statement of the International Society for Extracellular Vesicles and update of the MISEV2014 guidelines [Elektronisk resurs]

open access: yes, 2018
The last decade has seen a sharp increase in the number of scientific publications describing physiological and pathological functions of extracellular vesicles (EVs), a collective term covering various subtypes of cell-released, membranous structures ...
Bryl-Gorecka, Paulina,   +4 more
core   +1 more source

An epithelial GPR35 isoform supports tumor‐associated transcriptional and metabolic phenotypes

open access: yesFEBS Letters, EarlyView.
GPR35 generates two functionally distinct isoforms with previously unresolved roles. GPR35‐short mediates immune‐cell chemotaxis, while GPR35‐long is enriched in colorectal cancer epithelium, where it supports increased metabolism, proliferation, and tumor‐associated transcriptional programs.
Jørgen D. Rønneberg   +14 more
wiley   +1 more source

The extracellular enzymes of Coniophora cerebella [PDF]

open access: yesBiochemical Journal, 1966
1. The extracellular enzymes present in the culture filtrates of Coniophora cerebella grown on various carbohydrate carbon sources were investigated. Enzymes that degraded cellulose derivatives, hemicellulose fractions, starch, laminarin, pectin and several oligosaccharides were detected. 2.
openaire   +3 more sources

Discerning protein pools by selective staining with self‐labeling tags

open access: yesFEBS Letters, EarlyView.
Cell surface proteins have an intra‐ and extracellular pool. Combining genetic fusion to self‐labeling tags that can be addressed with small molecule fluorophores allows separating these pools. We highlight recent developments and techniques for state‐of‐the‐art interrogation of cell surface proteins in the complex tissue setting.
Kati Fischermanns, Johannes Broichhagen
wiley   +1 more source

Distinct RNA profiles in subpopulations of extracellular vesicles: apoptotic bodies, microvesicles and exosomes [PDF]

open access: yes, 2013
Introduction: In recent years, there has been an exponential increase in the number of studies aiming to understand the biology of exosomes, as well as other extracellular vesicles.
Szabó, Tamas G   +21 more
core   +1 more source

Temporal Variations in Soil Enzyme Activities and Responses to Land-Use Change in the Loess Plateau, China

open access: yesApplied Sciences, 2019
Variability in soil enzyme activity may have important implications for the knowledge of underground ecosystem functions driven by soil extracellular enzymes.
Jian Deng   +7 more
doaj   +1 more source

Scions impact biomass allocation and root enzymatic activity of rootstocks in grafted melon and watermelon plants

open access: yesFrontiers in Plant Science, 2022
Vegetable grafting is increasingly recognized as an effective and sustainable plant production alternative. Grafted plants usually show increased uptake of water and minerals compared with self-rooted plants, mostly thought a consequence of the vigorous ...
Glenda Sallaku   +3 more
doaj   +1 more source

Peripheral lysosomes recruit PLEKHG3 to focal adhesions and restrain protrusion dynamics

open access: yesFEBS Letters, EarlyView.
Proximity‐dependent labeling at the LAMTOR complex revealed the Rho GEF PLEKHG3 as a lysosome‐proximal protein directing the study toward the influence of lysosome positioning on actin dynamics and cell motility. We show that PLEKHG3 colocalizes with lysosomes at focal adhesion sites and observe that forced peripheral dispersion of lysosomes hinders ...
Rainer Ettelt   +8 more
wiley   +1 more source

Impact of Trametes versicolor and Phanerochaete chrysosporium on differential breakdown of pesticide mixtures in soil microcosms at two water potentials and associated respiration and enzyme activity. [PDF]

open access: yes, 2008
This study has examined the effect of inoculation of soil microcosms with Trametes versicolor and Phanerochaete chrysosporium on wood chips on differential degradation of pesticides (simazine, trifluralin and dieldrin, 10 mg kg−1 soil) at two water ...
Magan, Naresh, Fragoeiro, Silvia
core   +1 more source

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