Results 31 to 40 of about 71,340 (269)

Increased Extracellular Water in Normal-Appearing White Matter in Patients with Cerebral Small Vessel Disease

Journal of Integrative Neuroscience
Background: Microcirculatory variations have been observed in the normal-appearing white matter (NAWM) of individuals affected by cerebral small vessel disease (CSVD).
Shuqian Man, Songkuan Chen, Zhihua Xu, Hongxia Zhang, Zhenyu Cao   +4 more
doaj   +1 more source

Oral extracellular vesicles in early pregnancy can identify patients at risk of developing gestational diabetes mellitus.

PLoS ONE, 2019
AimTo isolate and characterize oral extracellular vesicles from gingival crevicular fluid at 11-14 weeks and evaluate their capacity to identify patients at risk of developing gestational diabetes mellitus.MethodsA case-control study was conducted ...
Lara J Monteiro, Manuel Varas-Godoy, Max Monckeberg, Ornella Realini, Marcela Hernández, Gregory Rice, Roberto Romero, José F Saavedra, Sebastián E Illanes, Alejandra Chaparro   +9 more
doaj   +1 more source

Bioimpedance spectroscopy for assessment of volume status in patients before and after general anaesthesia.

PLoS ONE, 2014
BackgroundTechnically assisted assessment of volume status before surgery may be useful to direct intraoperative fluid administration. We therefore tested a recently developed whole-body bioimpedance spectroscopy device to determine pre- to postoperative
Matthäus Ernstbrunner, Lisa Kostner, Oliver Kimberger, Peter Wabel, Marcus Säemann, Klaus Markstaller, Edith Fleischmann, Barbara Kabon, Manfred Hecking   +8 more
doaj   +1 more source

Is There Volume Transmission Along Extracellular Fluid Pathways Corresponding to the Acupuncture Meridians?

Journal of Acupuncture & Meridian Studies, 2017
Volume transmission is a new major communication signaling via extracellular fluid (interstitial fluid) pathways. It was proposed by the current authors that such pathways can explain the meridian phenomena and acupuncture effects. To investigate whether
Weibo Zhang, Ze Wang, Shuyong Jia, Yuying Tian, Guangjun Wang, Hongyan Li, Kjell Fuxe   +6 more
doaj   +1 more source

Modeling extracellular field potentials and the frequency-filtering properties of extracellular space [PDF]

Biophysics Journal 86 (2004) 1829-1842, 2003
Extracellular local field potentials (LFP) are usually modeled as arising from a set of current sources embedded in a homogeneous extracellular medium. Although this formalism can successfully model several properties of LFPs, it does not account for their frequency-dependent attenuation with distance, a property essential to correctly model ...
arxiv   +1 more source

Mechanical behavior of multi-cellular spheroids under osmotic compression [PDF]

, 2020
The internal and external mechanical environment plays an important role in tumorogenesis. As a proxy of an avascular early state tumor, we use multicellular spheroids, a composite material made of cells, extracellular matrix and permeating fluid. We characterize its effective rheology at the timescale of minutes to hours by compressing the aggregates ...
arxiv   +1 more source

Ablation of LRP6 in alpha‐smooth muscle actin‐expressing cells abrogates lung inflammation and fibrosis upon bleomycin‐induced lung injury

FEBS Letters, EarlyView.
Low‐density lipoprotein receptor‐related protein 6 (LRP6) is a key receptor for the Wnt antagonist Dickkopf1 (DKK1). DKK1 protein expression is induced in a bleomycin (BLM)‐induced lung injury model. We show that DKK1 induces proinflammatory and profibrotic genes in lung fibroblasts.
Eun‐Ah Sung, Mikhail G. Dozmorov, SuJeong Song, Theingi Aung, Min Hee Park, Patricia J. Sime, Wook‐Jin Chae   +6 more
wiley   +1 more source

Arterial vasodilation drives convective fluid flow in the brain: a poroelastic model

Fluids and Barriers of the CNS, 2022
The movement of fluid into, through, and out of the brain plays an important role in clearing metabolic waste. However, there is controversy regarding the mechanisms driving fluid movement in the fluid-filled paravascular spaces (PVS), and whether the ...
Ravi Teja Kedarasetti, Patrick J. Drew, Francesco Costanzo   +2 more
doaj   +1 more source

Procoagulant extracellular vesicles in amniotic fluid [PDF]

Translational Research, 2017
Embolization of amniotic fluid (AF) into the blood circulation leads to disseminated intravascular coagulation (DIC). Procoagulant phosphatidylserine (PS)- and tissue factor (TF)-exposing extracellular vesicles (EVs) might play an important role in AF embolism-induced DIC.
Lena Hell, Lukas Wisgrill, Cihan Ay, Andreas Spittler, Michael Schwameis, Bernd Jilma, Ingrid Pabinger, Peter Altevogt, Johannes Thaler   +8 more
openaire   +3 more sources

Making tau amyloid models in vitro: a crucial and underestimated challenge

FEBS Letters, EarlyView.
This review highlights the challenges of producing in vitro amyloid assemblies of the tau protein. We review how accurately the existing protocols mimic tau deposits found in the brain of patients affected with tauopathies. We discuss the important properties that should be considered when forming amyloids and the benchmarks that should be used to ...
Julien Broc, Clara Piersson, Yann Fichou
wiley   +1 more source