Results 111 to 120 of about 706,858 (272)

Dynamic Micromechanical Characterization of 3D Printed Bone In Vitro Models Manufactured via Vat Photopolymerization

open access: yesAdvanced Functional Materials, EarlyView.
This study presents a novel approach to designing and fabricating high‐porosity 3D‐printed scaffolds using a customized resin. Scaffold geometry, cellular interactions, and mechanical properties are analyzed to demonstrate these engineered bone models.
Sera Choi   +6 more
wiley   +1 more source

Covalent On‐Cell Conjugation of Biomaterials Through Oxidative Phenolic Coupling Regulates Stem Cell Fate via Intracellular Biophysical Programming

open access: yesAdvanced Functional Materials, EarlyView.
On‐cell covalent crosslinking of hydrogel matrix to the membrane of a single cell using droplet microfluidics enables mechanotransduction and influences stem cell fate. This newly established approach influences stem cell fate, independent of YAP/TAZ mechanotransduction and non‐covalent reversible binding ligands yet by various intracellular ...
Castro Johnbosco   +6 more
wiley   +1 more source

3D In Vitro Glioma‐Neuron‐Astrocyte Biomimetic Composites Recapitulate Key Molecular Mechanisms Linked to Glioblastoma Multiforme Pathophysiology

open access: yesAdvanced Functional Materials, EarlyView.
Glioblastoma multiforme is the most devastating and incurable brain tumor. To better study this disease, a 3D model is developed using a hyaluronic acid‐based hydrogel combined with a multicellular approach. This model recapitulates in vivo brain stiffness, cell‐extracellular matrix and cell‐cell interactions and the tumor's hijacking function with the
Mateo S. Andrade Mier   +26 more
wiley   +1 more source

Mesenchymal Stem Cells‐Derived Extracellular Vesicles Mimetics as Osteoinductive Mediators for Bone Healing

open access: yesAdvanced Functional Materials, EarlyView.
Mesenchymal stem cell‐derived nanoghosts (MSC‐NGs) mimic naturally secreted extracellular vesicles (MSC‐EVs) in structure and physicochemical properties but can be synthesized at more translatable yields. As osteogenic agents, MSC‐NGs demonstrate superior outcomes compared to MSC‐EVs.
Antoine Karoichan   +4 more
wiley   +1 more source

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