Results 121 to 130 of about 3,243,882 (355)
Extracellular Matrix Proteome Remodeling in Human Glioblastoma and Medulloblastoma
, 2021 Marina Trombetta-Lima +11 more
openalex +2 more sources
Exosome Proteomics of SOD1D90A Mutation Suggest Early Disease Mechanisms, and FN1 as a Biomarker
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Amyotrophic lateral sclerosis (ALS) is a neuromuscular disease. Super oxide dismutase 1 (SOD1) gene mutations cause ALS, and the D90A mutation is associated with primarily upper motor neuron (UMN) loss. Objective Our goal is to reveal the early cellular events in ALS pathology and identify potential pharmacokinetic biomarkers, using well ...
Mukesh Gautam +6 more
wiley +1 more source
siRNA-Targeting Transforming Growth Factor-β Type I Receptor Reduces Wound Scarring and Extracellular Matrix Deposition of Scar Tissue [PDF]
, 2014 Yi-Wen Wang +7 more
openalex +1 more source
SNUPN‐Related Muscular Dystrophy: Novel Phenotypic, Pathological and Functional Protein Insights
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective SNUPN‐related muscular dystrophy or LGMDR29 is a new entity that covers from a congenital or childhood onset pure muscular dystrophy to more complex phenotypes combining neurodevelopmental features, cataracts, or spinocerebellar ataxia. So far, 12 different variants have been described.
Nuria Muelas +18 more
wiley +1 more source
The interplay of fibroblasts, the extracellular matrix, and inflammation in scar formation
Journal of Biological Chemistry, 2021 Leandro Moretti +3 more
semanticscholar +1 more source
Function of Proteoglycans in the Extracellular Matrix.
THE JOURNAL OF THE STOMATOLOGICAL SOCIETY,JAPAN, 1993 Proteoglycans are glycosylated proteins which have cova‐lently attached highly anionic glycosaminoglycans. Many forms of proteoglycans are present In virtually all extracellular matrices of connective tissues. The major biological function of proteoglycans derives from the physicochemical characteristics of the glycosaminoglycan component of the ...
openaire +4 more sources
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Background There is growing recognition of the potential of plasma proteomics for Alzheimer's Disease (AD) risk assessment and disease characterization. However, differences between proteomics platforms introduce uncertainties regarding cross‐platform applicability.
Manyue Hu +9 more
wiley +1 more source