Results 141 to 150 of about 3,243,882 (355)

Understanding the extracellular matrix in acute myeloid leukemia

Haematologica, 2017
Valerio Izzi, Ritva Heljasvaara, Taina Pihlajaniemi   +2 more
doaj   +1 more source

Rigidity Matching between Cells and the Extracellular Matrix Leads to the Stabilization of Cardiac Conduction [PDF]

, 2012
Marcel Hörning, Satoru Kidoaki, Takahito Kawano, Kenichi Yoshikawa   +3 more
openalex   +1 more source

Extracellular Matrix and the Extracellular Environment [PDF]

PROTEOMICS, 2017
openaire   +2 more sources

What Is the Role of Giant Endosomal Sorting Complexes Required for Transport (ESCRT) Structures in T Cell Activation?

Advanced Biology, EarlyView.
The article explores the discovery of unusually large, ring‐shaped ESCRT protein structures formed by immune and stromal cells. It investigates their formation, composition, and potential roles in immune synapse formation. The findings challenge assumptions about their function in immunological synapses, suggesting an exclusive role in maintaining ...
Anthi Psoma, Femmy C. Stempels, Rinse de Boer, Geert van den Bogaart   +3 more
wiley   +1 more source

An extracellular matrix signature in leukemia precursor cells and acute myeloid leukemia

Haematologica, 2017
Valerio Izzi, Juho Lakkala, Raman Devarajan, Heli Ruotsalainen, Eeva-Riitta Savolainen, Pirjo Koistinen, Ritva Heljasvaara, Taina Pihlajaniemi   +7 more
doaj   +1 more source

CRTAP-Null Osteoblasts Have Increased Proliferation, Protein Secretion, and Skeletal Morphogenesis Gene Expression with Downregulation of Cellular Adhesion

Cells
Type VII osteogenesis imperfecta (OI), caused by recessive CRTAP mutations, is predominantly lethal in the first year of life. Due to its early lethality, little is known about bone dysplasia mechanism.
Aileen M. Barnes, Apratim Mitra, Marianne M. Knue, Alberta Derkyi, An Dang Do, Ryan K. Dale, Joan C. Marini   +6 more
doaj   +1 more source

Extracellular matrix: The driving force of mammalian diseases

, 2018
Renato V. Iozzo, Maria A. Gubbiotti
openalex   +2 more sources

The cell-assembled extracellular matrix: A focus on the storage stability and terminal sterilization of this human “bio” material

, 2023
Diane Potart, Maude Gluais, Alexandra Gaubert, Nicolas Da Silva, Marie Hourques, Marie Sarrazin, Julien Izotte, Léa Mora Charrot, Nicolas L’Heureux   +8 more
openalex   +1 more source

Primary Human Tissue Models for Metabolic Dysfunction‐Associated Liver Disease ‐ toward Streamlining Drug Discovery with Patient‐Derived Assays

Advanced Biology, EarlyView.
The review provides a critical up‐to‐date overview of the current landscape of human in vitro models for fatty liver disease, including spheroids, organoids, organ‐on‐a‐chip systems, bioprinted liver constructs and precision‐cut liver slices. Their utility for faithfully modeling different stages of MASLD and MASH are evaluated and their compatibility ...
Sonia Youhanna, Nayere Taebnia, Yingxin Liang, Ningtao Cheng, Yi Wang, Maurice Michel, Volker M. Lauschke   +6 more
wiley   +1 more source

A Spatially Resolved View on the Aging Substantia nigra: An Exploratory Proteomic Study

Advanced Biology, EarlyView.
Although aging is the most important risk factor for several neurodegenerative diseases, the molecular effects of physiological aging are still understudied. By applying spatially‐resolved proteomic analyses of the human substantia nigra pars compacta, alterations in vesicular trafficking and mitochondrial proteins are observed, as well as reduced ...
Britta Eggers, Maximilian Hausherr, Michel Lim, Karin Schork, Bilhan Karacora, Robin Grugel, Martin Eisenacher, Isabel Gil Aldea, Peter Riederer, Manfred Gerlach, Katrin Marcus   +10 more
wiley   +1 more source