Results 241 to 250 of about 2,138,893 (293)

HMGB1 as a danger signal in vascular remodeling. [PDF]

open access: yesKorean J Physiol Pharmacol
Kim JY, Sung H, Kim H, Bae SS, Kim CD.
europepmc   +1 more source

Decellularized Extracellular Matrix (ECM) as a Model to Study Fibrotic ECM Mechanobiology

2021
Aberrant deposition of the extracellular matrix (ECM) causes fibrosis and leads to ECM stiffening. This fibrotic ECM provides biological and biophysical stimulations to alter cell activity and drive progression of fibrosis. As an emerging discipline, mechanobiology aims to access the impact of both these cues on cell behavior and relates the ...
Chiuan-Ren, Yeh   +4 more
openaire   +2 more sources

The Extracellular Matrix (ECM) and Wound Healing: A Review

2023
The purpose of this article is to summarize current and historical literature demonstrating the role of the Extracellular Matrix (ECM) in the various stages of the wound healing cascade. ECM is a three-dimensional framework that is found in all human tissues.
Robert B Diller
exaly   +3 more sources

The Role of Mechanical Stimulation in Engineering of Extracellular Matrix (ECM)

2006 International Conference of the IEEE Engineering in Medicine and Biology Society, 2006
The engineering of ECM in vitro is a critical area of research in tissue engineering. Cells respond to mechanical stimuli and regulate the metabolic functions via mechanotransduction and synthesise ECM. This paper reviews key pathways. In vitro studies of mechanotransduction on macroscopic tissues in specialised automated bioreactors that are capable ...
Immanuel M. Sebastine, David J. Williams
openaire   +3 more sources

Kinetics for De-Extracellular Matrix(ECM)

MRS Advances, 2018
A kinetic model for ECM decellularization with Trypsin and Deoxycholic Acid as reactants in a batch system has been developed. The decellularization mechanism has been analysed by solving a series of ordinary differential equations relating heterogeneous reaction kinetics at the solid/liquid interface to mass transfer of reactant and products. In order
Namsoo P. Kim   +3 more
openaire   +1 more source

Extracellular Matrix (ECM) and the Sculpting of Embryonic Tissues

2018
Extracellular matrices (ECMs) are structurally and compositionally diverse networks of collagenous and noncollagenous glycoproteins, glycosaminoglycans, proteoglycans, and associated molecules that together comprise the metazoan matrisome. Proper deposition and assembly of ECM is of profound importance to cell proliferation, survival, and ...
Bette J, Dzamba, Douglas W, DeSimone
openaire   +2 more sources

Extracellular Matrix (ECM) and Cytoskeletal Modulation of Cellular Radiosensitivity

Acta Oncologica, 1997
Modulation of radiosensitivity by components of the extracellular matrix (ECM) and cytoskeletal elements has not been adequately studied. Although differences in the radiosensitivities of cells grown as monolayers, as spheroids, or grown in vitro in animal models are known, explanations have in the past neglected possible influences by the ECM and ...
A F, Stevenson, C S, Lange
openaire   +2 more sources

Extracellular matrix (ECM) stiffness and degradation as cancer drivers

Journal of Cellular Biochemistry, 2018
AbstractAlteration in the density and composition of extracellular matrix (ECM) occurs in tumors. The alterations toward both stiffness and degradation are contributed to tumor growth and progression. Cancer‐associated fibroblasts (CAFs) are the main contributors to ECM stiffness and degradation.
Masoud Najafi   +2 more
openaire   +2 more sources

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