Long non‐coding RNAs (lncRNAs) occupy an abundant fraction of the eukaryotic transcriptome and an emerging area in cancer research. Regulation by lncRNAs is based on their subcellular localization in HNSCC. This cartoon shows the various functions of lncRNAs in HNSCC discussed in this review.
Ellen T. Tran+3 more
wiley +1 more source
Stem cell‐based embryo models (SCBEMs) are valuable to study early developmental milestones. Matrigel, a basement membrane matrix, is a critical substrate used in various SCBEM protocols, but its role in driving stem cell lineage commitment is not clearly defined.
Atoosa Amel+3 more
wiley +1 more source
The proto-oncogene int-1 encodes a secreted protein associated with the extracellular matrix. [PDF]
Roger Bradley, Anthony M.C. Brown
openalex +1 more source
Degradation of connective tissue matrices by macrophages. III. Morphological and biochemical studies on extracellular, pericellular, and intracellular events in matrix proteolysis by macrophages in culture. [PDF]
We have shown that macrophages in culture degrade the glycoproteins and amorphous elastin of insoluble extracellular matrices. Ultrastructural observation of the macrophage-matrix interaction revealed that connective tissue macromolecules were ...
Bainton, DF, Jones, PA, Werb, Z
core
The impact of frailty syndrome on skeletal muscle histology: preventive effects of exercise
Frailty syndrome exacerbates skeletal muscle degeneration via increased ECM deposition and myofiber loss. This study, using a murine model, demonstrates that endurance exercise attenuates these histopathological alterations, preserving muscle integrity. Findings support exercise as a viable strategy to counteract frailty‐induced musculoskeletal decline
Fujue Ji+3 more
wiley +1 more source
Thymic "nurse" cells express extracellular matrix proteins
Dea Maria S. Villa-Verde, Wilson Savino
doaj +1 more source
Computation of Biological Conductance with Liouville Quantum Master Equation [PDF]
Recent experiments have revealed that single proteins can display high conductivity, which stays finite for low temperatures, decays slowly with distance, and exhibits a rich spatial structure featuring highly conducting and strongly insulating domains.
arxiv
Modulation of extracellular matrix proteins by endothelial cells undergoing angiogenesis in vitro. [PDF]
M. Luisa Iruela‐Arispe+2 more
openalex +1 more source
Understanding and Overcoming Immunotherapy Resistance in Skin Cancer: Mechanisms and Strategies
This narrative review explores the mechanisms driving immunotherapy resistance in skin cancer, including tumor microenvironment factors, genetic mutations, and immune evasion strategies. It highlights potential strategies to overcome resistance, offering insights for improving therapeutic outcomes and guiding future research in personalized ...
Shreya Singh Beniwal+8 more
wiley +1 more source
Activation of expression of genes coding for extracellular matrix proteins in Tat-producing glioblastoma cells. [PDF]
J. Paul Taylor+6 more
openalex +1 more source