Results 281 to 290 of about 866,232 (334)
Synthesis and assembly of mitochondrial proteins [PDF]
Das, Rathindra C.+3 more
core +1 more source
Engineering Assembloids to Mimic Graft‐Host Skeletal Muscle Interaction
This study develops a graft‐host skeletal muscle assembloid model combining neuromuscular organoids with tissue‐engineered constructs. Pre‐seeding decellularized muscles with myogenic cells enhances cell migration and axon invasion from the organoid. The model exhibits regenerative capacity following acute damage, advancing the understanding of human ...
Lucia Rossi+13 more
wiley +1 more source
Engineering the Future of Restorative Clinical Peripheral Nerve Surgery
What if damaged nerves could regenerate more effectively? This review unveils cutting‐edge strategies to restore nerve function, from biomaterial scaffolds and bioactive molecules to living engineered tissues. By accelerating axonal regrowth, preserving Schwann cells, and enhancing connectivity, these approaches are reshaping nerve repair—offering new ...
Justin C. Burrell+5 more
wiley +1 more source
The scaffold‐free Anchored Cell Sheet Engineering platform is used to create three‐dimensional (3D) in vitro models of skeletal muscle tissue that replicate key features of Duchenne and Myotonic dystrophies. These personalized tissue models, validated by histological, immunostaining, and proteomics analyses, accurately mimic disease phenotypes and ...
Alireza Shahin‐Shamsabadi+1 more
wiley +1 more source
EXTRACELLULAR MATRIX PROTEINS IN ORGAN TRANSPLANTATION1
Ana J. Coito+1 more
openalex +1 more source
Nanobubbles functionalized with indocyanine green and ischemic myocardium‐targeting peptide effectively target cardiomyocytes and enable the multimodal (fluorescence, ultrasonic, and photoacoustic) imaging of ischemic myocardium in mice with coronary microvascular dysfunction (CMD).
Bo Yu+8 more
wiley +1 more source
Volumetric muscle loss (VML) due to trauma or surgery, often leads to physical impairments. Traditional treatments rely on autologous flaps, limited by muscle availability often leading to donor site morbidity. This study presents multimodal bioprinting as an innovative approach for fabricating vascularized muscle flaps with 3D‐printed macrovessels ...
Eliana O. Fischer+8 more
wiley +1 more source
This perspective provides an overview of the growing interest in utilizing various gasotransmitters—small gaseous signaling molecules namely nitric oxide (NO), carbon monoxide (CO), and hydrogen sulfide (H2S)—for several therapeutic applications, with emphasis on the potential use of porous materials as carriers to provide safe and controlled local ...
Rosana V. Pinto+2 more
wiley +1 more source
The use of organ‐on‐a‐chip (OOC) microfluidic platforms is expanding in biomedical research. While this emerging technology is becoming increasingly accessible, the stability of long‐term functional cultures remains a critical challenge to address. This study presents a straightforward, one‐step method for the functionalization of polydimethylsiloxane ...
Mitzi Pérez‐Calixto+7 more
wiley +1 more source