Results 261 to 270 of about 565,976 (302)

The Biology of Extracellular Matrix Proteins in Hypertrophic Scarring

Advances in Wound Care, 2022
Significance: Hypertrophic scars (HTS) are a fibroproliferative disorder that occur following deep dermal injury and affect up to 72% of burn patients. These scars result in discomfort, impaired mobility, disruption of normal function and cosmesis, and significant psychological distress.
Elizabeth Eremenko, Jie Ding, Peter Kwan, Edward E. Tredget   +3 more
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Degradation of extracellular matrix proteins by hemorrhagic metalloproteinases

Archives of Biochemistry and Biophysics, 1989
The proteolytic activity of four hemorrhagic metalloproteinases (Ht-a, c, d, and e) isolated from the venom of the Western diamondback rattlesnake (Crotalus atrox) was investigated using isolated extracellular matrix (ECM) proteins. We determined that all of the proteinases are capable of cleaving fibronectin, laminin, type IV collagen, nidogen ...
E N, Baramova, J D, Shannon, J B, Bjarnason, J W, Fox   +3 more
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Extracellular Matrix Proteins and the Dynamics of Dentin Formation

Connective Tissue Research, 2002
Dentinogenesis involves controlled reactions that result in conversion of unmineralized predentin to dentin when apatite crystals are formed. This process is dynamic: Maturation events occur within predentin beginning at the proximal layer and progressing to the predentin-dentin (PD) border. One type of controlled reaction is the proteolytic processing
William T, Butler, Jan C, Brunn, Chunlin, Qin, Marc D, McKee   +3 more
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Extracellular Matrix Proteins Involved in Alzheimer's Disease

Chemistry – A European Journal, 2020
AbstractAlzheimer's disease (AD) is one of the most common neurodegenerative diseases and characterized by cognitive and memory impairments. Emerging evidence suggests that the extracellular matrix (ECM) in the brain plays an important role in the etiology of AD.
Jun Ma, Chao Ma, Jingjing Li, Yao Sun, Fangfu Ye, Kai Liu, Hongjie Zhang   +6 more
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Extracellular matrix proteins and leukocyte function

Journal of Leukocyte Biology, 1995
Abstract Extracellular matrix (ECM) proteins profoundly affect physiological functioning at the cellular level. Cell growth and differentiation, as well as cell shape and migration via the cytoskeleton, are all affected by ECM proteins.
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Binding of Haemophilus ducreyi to extracellular matrix proteins

Microbial Pathogenesis, 1992
A collection of Haemophilus ducreyi isolates were screened for the ability to bind to fibrinogen, fibronectin, collagen, gelatin and laminin by a particle agglutination test using latex beads coated with the individual proteins. Thirteen of 21 isolates reacted with all five extracellular matrix proteins.
D, Abeck, A P, Johnson, H, Mensing
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Adhesion of endothelial cells to extracellular matrix proteins

Journal of Cellular Physiology, 1983
AbstractHuman and bovine endothelial cells were used in a series of studies examining cell adhesion to extracellular matrix macromolecules. Collagen types I and III, an acetic acid extract of bovine lens capsule basement membrane, laminin, and fibronectin were demonstrated to affect, in varying degrees, cell adhesion, cell growth, and “sprout cell ...
E J, Macarak, P S, Howard
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Role of extracellular matrix proteins in heart function

Molecular and Cellular Biochemistry, 1993
The cardiac interstitium is populated by nonmyocyte cell types including transcriptionally active cardiac fibroblasts and endothelial cells. Since these cells are the source of many components of the cardiac extracellular matrix, and because changes in cardiac extracellular matrix are suspected of contributing to the genesis of cardiovascular ...
V, Pelouch, I M, Dixon, L, Golfman, R E, Beamish, N S, Dhalla   +4 more
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The Role of Extracellular Matrix Proteins in the Control of Phagocytosis

Journal of Leukocyte Biology, 1986
Abstract The phagocytic function of human-peripheral-blood-derived mononuclear and polymorphonuclear leukocytes can be regulated by external stimuli. In particular, the extracellular matrix (ECM) proteins fibronectin and laminin and serum amyloid P component can increase the phagocytic activity of these cells. Phagocytosis enhancement by
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Dynamics of Assembly and Reorganization of Extracellular Matrix Proteins

2006
This chapter will review advances in our understanding of the dynamics of assembly and reorganization of extracellular matrix (ECM) proteins and will highlight the role of fibronectin as a key orchestrator for the assembly of multiple ECM proteins.
Sarah L, Dallas, Qian, Chen, Pitchumani, Sivakumar   +2 more
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