Results 11 to 20 of about 4,618,222 (282)
An Isotonic Model of Neuron Swelling Based on Co-Transport of Salt and Water
Membranes, 2023 Neurons spend most of their energy building ion gradients across the cell membrane. During energy deprivation the neurons swell, and the concomitant mixing of their ions is commonly assumed to lead toward a Donnan equilibrium, at which the concentration ...
Reinoud Maex
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New Insights into Alzheimer’s Disease: Novel Pathogenesis, Drug Target and Delivery
Pharmaceutics, 2023 Alzheimer’s disease (AD), the most common type of dementia, is characterized by senile plaques composed of amyloid β protein (Aβ) and neurofilament tangles derived from the hyperphosphorylation of tau protein.
Haishu Chen +7 more
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Unconventional Pathways of Protein Secretion: Mammals vs. Plants
Frontiers in Cell and Developmental Biology, 2022 In eukaryotes, many proteins contain an N-terminal signal peptide that allows their translocation into the endoplasmic reticulum followed by secretion outside the cell according to the classical secretory system. However, an increasing number of secreted
Elisa Maricchiolo +5 more
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Frontiers in Oncology, 2023 ObjectivesTo evaluate whether tumor extracellular volume fraction (fECV) on contrast-enhanced computed tomography (CT) aids in the differentiation between intrahepatic cholangiocarcinoma (ICC) and hepatocellular carcinoma (HCC).MethodsIn this ...
T. Honda +12 more
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Diffusion in Brain Extracellular Space [PDF]
Physiological Reviews, 2008 Diffusion in the extracellular space (ECS) of the brain is constrained by the volume fraction and the tortuosity and a modified diffusion equation represents the transport behavior of many molecules in the brain. Deviations from the equation reveal loss of molecules across the blood-brain barrier, through cellular uptake, binding, or other mechanisms ...
Eva, Syková, Charles, Nicholson
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Characterization of extracellular vesicles and synthetic nanoparticles with four orthogonal single-particle analysis platforms [PDF]
, 2021 Ingreso parcial de los coautores.We compared four orthogonal technologies for sizing, counting, and phenotyping of extracellular vesicles (EVs) and synthetic particles.
Dong, Liang +5 more
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Frontiers in Neurology, 2021 Interictal spikes (IISs) may result from a disturbance of the intimate functional balance between various neuronal (synaptic and non-synaptic), vascular, and metabolic compartments.
Cristian Arnal-Real +4 more
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Exploring the Dynamics of Brain Extracellular Space. [PDF]
Biophys J, 2019 Pajevic S.
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Brain extracellular space as a diffusion barrier [PDF]
Computing and Visualization in Science, 2011 The extracellular space (ECS) consists of the narrow channels between brain cells together with their geometrical configuration and contents. Despite being only 20-60 nm in width, the ECS typically occupies 20% of the brain volume. Numerous experiments over the last 50 years have established that molecules moving through the ECS obey the laws of ...
Charles Nicholson +2 more
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A new model for computing the evolution of the extracellular, innercellular and membrane potential simultaneously [PDF]
, 2010 Poster Presentation from Nineteenth Annual Computational Neuroscience Meeting: CNS*2010 San Antonio, TX, USA. 24-30 July 2010 In order to model extracellular potentials the Line-Source method provides [1] a very powerful and accurate approach.
Konstantinos Xylouris +3 more
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