Results 71 to 80 of about 596,635 (290)

A three-dimensional mathematical model for the signal propagation on a neuron’s membrane.

open access: yesFrontiers in Computational Neuroscience, 2015
In order to be able to examine the extracellular potential's influence on network activity and to better understand dipole properties of the extracellular potential, we present and analyze a three-dimensional formulation of the cable equation which ...
Konstantinos eXylouris, Gabriel eWittum
doaj   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

open access: yesMolecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Epithelial sodium channels (ENaC) produce extracellular positive DC potentials in the retinal neuroepithelium

open access: yesData in Brief, 2016
Positive DC (direct current) potentials were measured in the extracellular space in the retinal neuroepithelium of chick embryos. The positive DC potential was suppressed by amiloride, a blocker for epithelial Na+ channels (ENaC).
Masayuki Yamashita
doaj   +1 more source

Molecular Mechanisms Mediating the Transfer of Disease-Associated Proteins and Effects on Neuronal Activity

open access: yesJournal of Parkinson’s Disease, 2022
Background: Various cellular pathways have been implicated in the transfer of disease-related proteins between cells, contributing to disease progression and neurodegeneration. However, the overall effects of protein transfer are still unclear. Objective:
Inês C. Brás   +11 more
doaj   +1 more source

Generalized cable formalism to calculate the magnetic field of single neurons and neuronal populations

open access: yes, 2014
Neurons generate magnetic fields which can be recorded with macroscopic techniques such as magneto-encephalography. The theory that accounts for the genesis of neuronal magnetic fields involves dendritic cable structures in homogeneous resistive ...
Bedard, Claude, Destexhe, Alain
core   +1 more source

A control algorithm for autonomous optimization of extracellular recordings [PDF]

open access: yes, 2006
This paper develops a control algorithm that can autonomously position an electrode so as to find and then maintain an optimal extracellular recording position.
Burdick, Joel W., Nenadic, Zoran
core   +2 more sources

Extracellular space in some isolated tissues [PDF]

open access: yesThe Journal of Physiology, 1974
1. The spaces occupied by isotopically labelled inulin, polyethylene glycol, mol. wt. 4000 (PEG 4000), polyethylene glycol, mol. wt. 1000 (PEG 1000) and sucrose in metabolizing mammalian kidney and liver slices and in toad bladder epithelial cell preparations incubated in vitro have been examined.2.
D J, McIver, A D, Macknight
openaire   +2 more sources

EDNRB‐dependent endothelin signaling reduces proliferation and promotes proneural‐to‐mesenchymal transition in gliomas

open access: yesMolecular Oncology, EarlyView.
Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau   +36 more
wiley   +1 more source

Dissecting the Simultaneous Extracellular/Intracellular Contributions to Cr(VI) Reduction under Aerobic and Anaerobic Conditions Using the Newly Isolating Cr(VI)-Reducing Bacterium of Pseudomonas sp. HGB10

open access: yesMicroorganisms
Quantifying extracellular and intracellular contributions to Cr(VI) reduction is crucial for understanding bacterial Cr(VI)-reduction mechanisms. However, this contribution under different oxygen conditions remains largely unexplored.
Shenglei Chen   +4 more
doaj   +1 more source

Circadian rhythm and sleep-wake systems share the dynamic extracellular synaptic milieu

open access: yesNeurobiology of Sleep and Circadian Rhythms, 2018
The mammalian circadian and sleep-wake systems are closely aligned through their coordinated regulation of daily activity patterns. Although they differ in their anatomical organization and physiological processes, they utilize overlapping regulatory ...
Joanna M. Cooper   +2 more
doaj   +1 more source

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