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Extracellular Vesicles and Glycosylation
2021Extracellular vesicles (EVs), a generic term for any vesicles or particles that are released from cells, play an important role in modulating numerous biological and pathological events, including development, differentiation, aging, thrombus formation, immune responses, neurodegenerative diseases, and tumor progression.
Yoichiro, Harada +4 more
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Extracellular Vesicle and Lipoprotein Interactions
Nano Letters, 2023Extracellular vesicles and lipoproteins are lipid-based biological nanoparticles that play important roles in (patho)physiology. Recent evidence suggests that extracellular vesicles and lipoproteins can interact to form functional complexes. Such complexes have been observed in biofluids from healthy human donors and in various in vitro disease models ...
Raluca E. Ghebosu +2 more
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Extracellular vesicles in atherosclerosis
Clinica Chimica Acta, 2019Extracellular vesicles (EVs), which exist in human blood, are increased in some inflammation-related cardiovascular diseases. EVs are involved in inflammation, immunity, signal transduction, cell survival and apoptosis, angiogenesis, thrombosis, and autophagy, all of which are highly significant for maintaining homeostasis and disease progression ...
WenYi Deng +6 more
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Extracellular vesicles in leukemia
Leukemia Research, 2018Extracellular vesicles (EV) are nano-sized membrane enclosed vehicles that are involved in cell-to-cell communication and carry cargo that is representative of the parent cell. Recent studies have highlighted the significant roles leukemia EVs play in tumor progression, and ways in which they can lead to treatment evasion, thus meriting further ...
Alejandro, Pando +3 more
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Extracellular vesicles in plants
Molecular PlantExtracellular vesicles (EVs) are cell released lipid-wrapped nano- to micro-sized particles without self-replication ability. Plant cells secrete EVs (PEVs) during normal developmental stage and in response to external stimuli. Distinct from plant-derived nanoparticles (PDNP), here we narrow the definition of PEVs which are naturally secreted by cells,
Ning-Jing Liu, Li-Pan Hou, Xiao-Ya Chen
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Role of Extracellular Vesicle Surface Proteins in the Pharmacokinetics of Extracellular Vesicles
Molecular Pharmaceutics, 2018Extracellular vesicles (EVs) are small membrane vesicles secreted from cells and have great potential as drug delivery carriers. Surface proteins on EV membranes might play roles in pharmacokinetics. One method which can be used to study the role of surface membrane of EV is to modify the inner space of EV.
Chonlada Charoenviriyakul +4 more
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From intra- to extracellular vesicles: extracellular vesicles in developmental signalling
Essays in Biochemistry, 2018Signalling from cell-to-cell is fundamental for determining differentiation and patterning. This communication can occur between adjacent and distant cells. Extracellular vesicles (EVs) are membrane-based structures thought to facilitate the long-distance movement of signalling molecules. EVs have recently been found to allow the transport of two major
Gradilla, Ana-Citlali +3 more
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Extracellular vesicle autoantibodies
Journal of AutoimmunityAutoantibodies are immunoglobulin proteins produced by autoreactive B cells responding to self-antigens. Extracellular vesicles (EVs) are membranous structures released by almost all types of cells and extensively distributed in various biological fluids. Studies have indicated that EVs loaded with self-antigens not only play important roles in antigen
Yan, Hua +3 more
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An immunoassay for urinary extracellular vesicles
American Journal of Physiology-Renal Physiology, 2016Although nanosized urinary extracellular vesicles (uEVs) are increasingly used for biomarker discovery, their isolation currently relies on time-consuming techniques hindering high-throughput application. To navigate this problem, we designed an immunoassay to isolate, quantify, and normalize uEV proteins.
Salih, Mahdi +7 more
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Extracellular vesicles: Specialized bone messengers
Archives of Biochemistry and Biophysics, 2014Mammalian cells actively secrete factors that contribute to shape their microenvironment. These factors either travel freely or they are enclosed within the lipid bilayer of extracellular vesicles (EVs), and regulate the function of neighboring and distant cells.
Jess Morhayim +2 more
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