Results 261 to 270 of about 209,873 (358)

The Reconstruction of Peripheral Auditory Circuit: Recent Advances and Future Challenges

Advanced Science, EarlyView.
This paper summarizes the potential of biomaterials, stem cells, and gene editing technologies in the regeneration of inner ear hair cells, spiral ganglion neurons, and inner ear organoids. Challenges and potential developments are discussed and explored.
Zhe Li, Ying Zhang, Zhenyu Xiao, Jieyu Qi   +3 more
wiley   +1 more source

The Potential of Extracellular Vesicle-Mediated Spread of Self-Amplifying RNA and a Way to Mitigate It. [PDF]

Int J Mol Sci
Federico M.
europepmc   +1 more source

Transferred BCR/ABL DNA from K562 Extracellular Vesicles Causes Chronic Myeloid Leukemia in Immunodeficient Mice

, 2014
Jin Cai, Gengze Wu, Xiaorong Tan, Yu Han, Caiyu Chen, Chuanwei Li, Na Wang, Xue Zou, Xinjian Chen, Faying Zhou, Duofen He, Lin Zhou, Pedro A. José, Chunyu Zeng   +13 more
openalex   +2 more sources

Rational Design of Inner Ear Drug Delivery Systems

Advanced Science, EarlyView.
Hearing loss is a common disease affecting many people, and inner ear lesions are one of the most important causes. This review focuses on the treatment of inner ear hearing loss by drug delivery systems. It includes the current methods and technologies developed, and it predicts possible directions.
Xiayidan Maimaitikelimu, Zhiyan Xuan, Haoyu Ren, Keng Chen, Hui Zhang, Huan Wang   +5 more
wiley   +1 more source

An Extracellular Vesicle (EV) Paper Strip for Rapid and Convenient Estimation of EV Concentration. [PDF]

Biosensors (Basel)
Ströhle G, Goodrum R, Li H.
europepmc   +1 more source

Exome Sequencing Reveals the Genetic Architecture of Non‐syndromic Orofacial Clefts and Identifies BOC as a Novel Causal Gene

Advanced Science, EarlyView.
Nonsyndromic orofacial clefts (NSOFCs) are the most common craniofacial defects. Exome sequencing of 214 sporadic cases sheds new light on its genetic architecture and identifies many candidate pathogenic variants. Furthermore, functional studies establish BOC as a novel causal gene and reveal an unusual two‐locus model of inheritance via the epistatic
Qing He, Min Yu, Yuhua Jiao, Yizhu Xu, Xuqin Liang, Wenbin Huang, Linping Xu, Yuxia Hou, Zhanping Ren, Beile Lyu, Zhenwei Qian, Pengpeng Liu, Jing Zhou, Huimei Huang, Chunyan Yin, Huaxiang Zhao, Yi Ding   +16 more
wiley   +1 more source

MicroRNA-371-373 cluster extracellular vesicle-based communication in testicular germ cell tumors. [PDF]

Cell Commun Signal
Tavares NT, Lourenço C, Constâncio V, Fernandes-Pontes F, Fonseca D, Silva-Santos R, Braga I, Maurício J, Henrique R, Liu M, Weiss RS, Bagrodia A, Jerónimo C, Lobo J.   +13 more
europepmc   +1 more source

Isolation of Urinary Extracellular Vesicles from Tamm- Horsfall Protein–depleted Urine and their Application in the Development of a Lectin-Exosome-Binding Assay

, 2014
Maja Kosanović, Miroslava Janković
openalex   +1 more source

Accurate Delivery of Mesenchymal Stem Cell Spheroids With Platelet‐Rich Fibrin Shield: Enhancing Survival and Repair Functions of Sp‐MSCs in Diabetic Wound Healing

Advanced Science, EarlyView.
Autologous plasma‐derived platelet‐rich fibrin (PRF) is prepared as a protective shield for mesenchymal stem cell spheroids (Sp‐MSCs). PRF forms a fibrin shield to protect Sp‐MSCs from the oxidative stress environment. The nutrients in PRF, particularly the α‐granules, can enhance the repair function of Sp‐MSCs.
Jinglve Zhang, Wenqing Xu, Yutian Xiao, Dingheng Su, Yusheng He, Huohong Yang, Yixin Xie, Xiaofang Wang, Ren‐He Xu, Shaorong Lei, Dingyu Wu   +10 more
wiley   +1 more source

Injectable extracellular vesicle hydrogels with tunable viscoelasticity for depot vaccine. [PDF]

Nat Commun
Bhatta R, Han J, Liu Y, Bo Y, Wang Y, Nguyen D, Chen Q, Wang H.   +7 more
europepmc   +1 more source