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Opportunities and challenges in studying the extracellular vesicle corona
Nature Cell Biology, 2022 The extracellular vesicle (EV) surface corona is emerging as a crucial mediator of EV functions. This Comment discusses the roles and biogenesis of the EV corona, as well as the importance of controls to determine whether a biological effect is ...
E. Buzás
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Protoplasma, 2019
Exocytosis is a key mechanism for delivering materials into the extracellular space for cell function and communication. In plant cells, conventional protein secretion (CPS) is achieved via an ER (endoplasmic reticulum)-Golgi-TGN (trans-Golgi network)-PM (plasma membrane) pathway.
Yong, Cui +3 more
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Exocytosis is a key mechanism for delivering materials into the extracellular space for cell function and communication. In plant cells, conventional protein secretion (CPS) is achieved via an ER (endoplasmic reticulum)-Golgi-TGN (trans-Golgi network)-PM (plasma membrane) pathway.
Yong, Cui +3 more
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Extracellular Vesicles and Hypertension
2023Hypertension implicates multiple organs and systems, accounting for the majority of cardiovascular diseases and cardiac death worldwide. Extracellular vesicles derived from various types of cells could transfer a variety of substances such as proteins, lipids, and nucleic acids from cells to cells, playing essential roles in both physiological and ...
Heng, Tang, Yuxue, Hu, Jiali, Deng
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Extracellular Vesicles and Obesity
2023Extracellular vesicles (EVs) are a group of vesicles with membrane structure released by cells, including exosomes, microvesicles, apoptotic bodies, and oncosomes. EVs are now recognized as important tools of cell-to-cell communication, allowing cells to exchange proteins, lipids, and genetic material to participate in physiological and pathological ...
Kai, Wang, Cong, Zeng
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Extracellular vesicles in atherosclerosis
Clinica Chimica Acta, 2019Extracellular vesicles (EVs), which exist in human blood, are increased in some inflammation-related cardiovascular diseases. EVs are involved in inflammation, immunity, signal transduction, cell survival and apoptosis, angiogenesis, thrombosis, and autophagy, all of which are highly significant for maintaining homeostasis and disease progression ...
WenYi Deng +6 more
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Biogenesis of Extracellular Vesicles
2021Extracellular vesicles (EVs) refer to vesicles that are released by cells into the extracellular space. EVs mediate cell-to-cell communication via delivery of functional biomolecules between host and recipient cells. EVs can be categorised based on their mode of biogenesis and secretion and include apoptotic bodies, ectosomes or shedding microvesicles ...
Taeyoung, Kang +2 more
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Extracellular Vesicles and Glycosylation
2021Extracellular vesicles (EVs), a generic term for any vesicles or particles that are released from cells, play an important role in modulating numerous biological and pathological events, including development, differentiation, aging, thrombus formation, immune responses, neurodegenerative diseases, and tumor progression.
Yoichiro, Harada +4 more
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Extracellular Vesicles in Hemostasis
Clinics in Laboratory MedicineExtracellular vesicles (EVs) are key modulators of hemostasis, influencing coagulation under physiologic and pathologic conditions. Depending on their cellular origin and their releasing conditions, EVs promote coagulation predominantly by the exposure of phosphatidylserine and tissue factor.
Marwa, Mostageer +2 more
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Extracellular vesicle autoantibodies
Journal of AutoimmunityAutoantibodies are immunoglobulin proteins produced by autoreactive B cells responding to self-antigens. Extracellular vesicles (EVs) are membranous structures released by almost all types of cells and extensively distributed in various biological fluids. Studies have indicated that EVs loaded with self-antigens not only play important roles in antigen
Yan, Hua +3 more
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Extracellular vesicles in leukemia
Leukemia Research, 2018Extracellular vesicles (EV) are nano-sized membrane enclosed vehicles that are involved in cell-to-cell communication and carry cargo that is representative of the parent cell. Recent studies have highlighted the significant roles leukemia EVs play in tumor progression, and ways in which they can lead to treatment evasion, thus meriting further ...
Alejandro, Pando +3 more
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