Results 291 to 300 of about 209,873 (358)

Extracellular Vesicle-Liposome-Darunavir Formulation for the Treatment of HIV Neuropathogenesis. [PDF]

ACS Appl Nano Mater
Zhou L, Godse S, Sinha N, Ma D, Mirzahosseini G, Salman M, Pulliam P, Tan C, Singh UP, Ishrat T, Kochat H, Kumar S.   +11 more
europepmc   +1 more source

MTFR2‐Mediated Fission Drives Fatty Acid and Mitochondrial Co‐Transfer from Hepatic Stellate Cells to Tumor Cells Fueling Oncogenesis

Advanced Science, EarlyView.
In the tumor margin of hepatocellular carcinoma (HCC), activated hepatic stellate cells upregulate MTFR2, initiating inhibiting DRP1 degradation and mitochondrial fission. This enhances mitochondrial availability and facilitates FAs synthesis via ACC1. Additionally, fission promotes RAC1‐mediated cytoskeletal remodeling and Miro1‐mediated mitochondrial
La Zhang, Baoyong Zhou, Jun Yang, Cong Ren, Jing Luo, Zhenghang Li, Qiang Liu, Zuotian Huang, Zhongjun Wu, Ning Jiang   +9 more
wiley   +1 more source

Extracellular Vesicle Glial Fibrillary Acidic Protein as a Circulating Biomarker of Traumatic Brain Injury Severity. [PDF]

J Mol Neurosci
Babaee A, Wichmann TO, Rasmussen MM, Brink O, Olsen DA, Borris LC, Lesbo M, Rasmussen RW, Salomon C, Handberg A, Mellergaard M, Hviid CVB.   +11 more
europepmc   +1 more source

Recent Advances in mRNA Delivery Systems for Cancer Therapy

Advanced Science, EarlyView.
This review systematically investigates the applications of mRNA therapy in cancer treatment, with particular emphasis on nonviral delivery systems, targeting strategies, stimulus‐responsive systems, and local delivery methods. Concluding with a meticulous evaluation, the review sheds light on the prevailing challenges while illuminating promising ...
Zheng Zhang, Ya‐Nan Fan, Si‐Qi Jiang, Ya‐Jing Ma, Yao‐Ru Yu, Yu‐Xin Qing, Qian‐Ru Li, Yi‐Lin Liu, Song Shen, Jun Wang   +9 more
wiley   +1 more source

Mechanistic insight into human milk extracellular vesicle-intestinal barrier interactions. [PDF]

J Extracell Biol
Luo X, Zhang Y, Ding N, Javorovic J, Raimi-Abraham BT, Lynham S, Yang X, Shenker N, Vllasaliu D.   +8 more
europepmc   +1 more source

Engineered Tissue Models to Decode Host–Microbiota Interactions

Advanced Science, EarlyView.
Host–Microbiota interactions in the human body. Created in BioRender. Ghezzi, C. (2025) https://BioRender.com/ihivskg. Abstract A mutualistic co‐evolution exists between the host and its associated microbiota in the human body. Bacteria establish ecological niches in various tissues of the body, locally influencing their physiology and functions, but ...
Miryam Adelfio, Grace E. Callen, Xuesong He, Bruce J. Paster, Hatice Hasturk, Chiara E. Ghezzi   +5 more
wiley   +1 more source

Novel Detection and Clinical Utility of Serum-Derived Extracellular Vesicle in Angiosarcoma. [PDF]

Acta Derm Venereol
Yokoi K, Wang J, Yoshioka Y, Fujisawa Y, Fujimoto M, Ochiya T, Tanemura A.   +6 more
europepmc   +1 more source

Bioengineered Tumor‐Derived Extracellular Vehicles Suppressed Colorectal Cancer Liver Metastasis and Bevacizumab Resistance

Advanced Science, EarlyView.
The upregulated CCL24 in CRC liver metastasis promotes the formation of inflammatory tumor‐associated fibroblast subsets and induces resistance to bevacizumab therapy. Downregulation of CCL24 significantly increased sensitivity to antiangiogenic therapy in CRC mouse model. Hence, a novel therapeutic target is identified for patients with CRC with liver
Junjiang Wang, Chunsheng Liu, Ping Wang, Zhiyuan Liu, Weixian Hu, Zejian Lv, Chengzhi Huang, Xueqing Yao   +7 more
wiley   +1 more source

Artificial Cell-Derived Vesicles: Extracellular Vesicle Mimetics for Chondrocyte Restoration in TMJOA Therapy. [PDF]

Int J Nanomedicine
Hu Y, Huang G, Dai Z, Yang R, Zhang Y, Zhang Y, Shen H, Pu Z, Ma L, Li S.   +9 more
europepmc   +1 more source