Results 211 to 220 of about 247,554 (291)

Extracellular vesicles and mitochondria in central nervous system diseases. [PDF]

J Cereb Blood Flow Metab
Park JH, Back DB, Hamanaka G, Ishikane S, Hayakawa K.   +4 more
europepmc   +1 more source

Supplementary Figure 7 and 8 from Antigen-Loaded Extracellular Vesicles Induce Responsiveness to Anti–PD-1 and Anti–PD-L1 Treatment in a Checkpoint Refractory Melanoma Model

Rosanne E. Veerman, Gözde Güçlüler Akpinar, Annemarijn Offens, Loïc Steiner, Pia Larssen, Andreas Lundqvist, Mikael C. I. Karlsson, Susanne Gabrielsson   +7 more
openalex   +1 more source

Tailoring Vascular‐Immune Homeostasis via Manganese‐DNA Complex‐Armed Immunogenic Extracellular Vesicles for Pancreatic Cancer Immunotherapy

Advanced Science, EarlyView.
This study demonstrates that Mn2⁺–tumor DNA complexes encapsulated in dendritic cell (DC)– derived immunogenic extracellular vesicles (EVDC@Mn‐DNA) act as a DC‐specific cGAS– STING activator. EVDC@Mn‐DNA treatment enhances intratumoral DC activation, improves tumor vascular function, promotes CD8⁺ T cell activity, and suppresses pancreatic tumor growth,
Xue Jiang, Lihuan Shang, Xiaochun Chen, Xiangzhan Kong, Xiaojuan Wang, Linjia Jiang, Huiying Zhao, Yafeng Zhu, Cheng Huang, Shiyi Deng, Rui Zhang, Minghui Wang, Haoming Lin, Ping‐Pui Wong   +13 more
wiley   +1 more source

Extracellular Vesicles as Therapeutic Strategy for Ischemic Stroke. [PDF]

J Neurochem
da Silva EA, Figueiredo JCQ, Rossi EA, Cunha RS, Sanches FS, de Lima AVR, Loiola EC, Costa-Ferro ZSM, Souza BSF.   +8 more
europepmc   +1 more source

Figure S6 from Extracellular Vesicle–Packaged miR-99a Reprograms Fibroblasts to Create an Inflammatory Niche That Drives Colorectal Cancer Metastasis

Mingzhen Zhou, Hao Liu, Juan Hui, Qing Chen, Yihan Zhao, Haojia Wang, W.‐Z. Liu, Yibo Bian, Songtao Ji, Boda Wang, Yangsong He, Ge Miao Miao, Yi Liu, Yongzhan Nie, Hua Han, Stephan Emmrich, Xin Wang, Yuanyuan Lu, Xiaodi Zhao   +18 more
openalex   +1 more source

YKT6 Promotes Bladder Cancer Progression by Stabilizing β‐catenin Through USP7‐Mediated Deubiquitination

Advanced Science, EarlyView.
The SNARE protein YKT6 is upregulated in bladder cancer (BLCA), correlating with poor prognosis. YKT6 promotes tumor proliferation and metastasis by activating Wnt/β‐catenin signaling. It recruits Ubiquitin‐Specific Peptidase 7 (USP7) to deubiquitinate and stabilize β‐catenin, enhancing its nuclear accumulation and driving oncogenic gene expression ...
Sheng Tu, Wenzhi Du, Yongwen Luo, Jiageng Shi, Tianyun Liu, Meng Ji, Kangping Xiong, Siming Chen, Fenfang Zhou, Mingxing Li, Jingtian Yu, Gang Wang, Lingao Ju, Yi Zhang, Yu Xiao, Xinghuan Wang, Kaiyu Qian   +16 more
wiley   +1 more source

From Microbiota to Cancer: Role of Extracellular Vesicles in Gut-Lung Axis. [PDF]

Cancers (Basel)
Albano GD, Taverna S.
europepmc   +1 more source

Extracellular vesicles in multiple sclerosis: what are they telling us?

, 2014
Matías eSáenz-Cuesta, Iñaki eOsorio-Querejeta, David eOtaegui   +2 more
openalex   +1 more source

A Unique Chimeric RNA: ERCC1‐iASPP Drives Benzo[a]pyrene‐Induced Lung Carcinogenesis via Dual Coding and Non‐Coding Mechanisms

Advanced Science, EarlyView.
The chimeric RNA ERCC1‐iASPP possesses dual coding and non‐coding functions, synergistically accelerating the process of cellular malignant transformation. Abstract Genetic variation at 19q13.3 critically modulates chemical carcinogen‐induced lung carcinogenesis, particularly in mediating the activity of benzo[a]pyrene (B[a]P), a major polycyclic ...
Mingming Shan, Mingyang Xiao, Liang Zhang, Shen Wang, Jiahang Wu, Kang Cao, Yujin Li, Guopei Zhang, Junwei Xie, Xiaobo Lu   +9 more
wiley   +1 more source

Extracellular vesicles in reproductive medicine: from "animal-led" to "plant-enabled". [PDF]

Front Cell Dev Biol
Pan K, Ju W, Wang Y, Zhang Q, Wang R, Jiang X, Zhao S.   +6 more
europepmc   +1 more source