Results 261 to 270 of about 412,727 (336)

The Role of Extracellular Vesicles as Diagnostic Tools in Gut-Brain Axis Disorders. [PDF]

Mol Neurobiol
da Costa PM, Nunes PIG, Ciurleo GCV, Junior JWLT, Neto PB, Belayev L, Oriá RB.   +6 more
europepmc   +1 more source

Exclusive Breastfeeding Drives AMPK‐Dependent Thermogenic Memory in BAT and Promotes Long‐Term Metabolic Benefits in Offspring

Advanced Science, EarlyView.
Exclusive breastfeeding establishes a thermogenic memory in brown adipose tissue by activating the HIF1AN/AMPK/α‐ketoglutarate axis via milk‐derived extracellular vesicles enriched in miR‐125a‐5p. This programming preserves metabolic health, while αKG supplementation restores BAT function under mixed feeding, offering strategies to mitigate the ...
Ningxi Wu, Anwen Yin, Xiang Yu, Mingxin Wang, Jiahui Zhang, Kerong Liu, Yutong Hou, Minkai Cao, Yiting Zhang, Xiaoxiao Zhang, Yao Gao, Xirong Guo, Le Zhang, Yun Li   +13 more
wiley   +1 more source

TMEM131‐Mediated Soluble TRAIL Triggered Type II Alveolar Epithelial Cell Senescence in Radiation‐Induced Lung Injury

Advanced Science, EarlyView.
TMEM131 recruits the COPII complex to accelerate TRAIL transportation from endoplasmic reticulum to Golgi apparatus, and promotes soluble TRAIL secretion. TRAIL inhibits mitophagy and induces senescence through DR5 receptor in type II alveolar epithelial cells, ultimately driving radiation‐induced lung injury (RILI) progression.
Linzhi Han, Chunsheng Wang, Xiuli Guo, Yuan Luo, Jianguo Zhang, Fajian He, Zihang Zeng, Jiang Luo, Wen Ouyang, Yan Gong, Conghua Xie   +10 more
wiley   +1 more source

Exploring the Spatial Limits of Extracellular Vesicles-Mediated Intercellular Communication. [PDF]

J Extracell Vesicles
Colombo F, Nimkar K, Norton EG, Lovat F, Cocucci E.   +4 more
europepmc   +1 more source

CX3CR1+/UCHL1+ microglial extracellular vesicles in blood: a potential biomarker for multiple sclerosis [PDF]

Jing Duan, Aowei Lv, Zhen Guo, Qi Liu, Chen Tian, Ying Yang, Bi Jin, Xintong Yu, Guoping Peng, Benyan Luo, Zhijian Cai, Bin Xu, Ying Fu, Jing Zhang   +13 more
openalex   +1 more source

Dysregulation of CircZNF79(5) Modulates YBX1 Stability and Selective Autophagy to Drive Hepatocellular Carcinoma Progression

Advanced Science, EarlyView.
In HCC, circZNF79(5) binds to YBX1 and functions as an oncogene, recruits BRCC36 to remove K63‐linked ubiquitin chains to stabilize YBX1 protein, and promotes HCC progression via the HIF‐1 signaling pathway. Conversely, circZNF79(5) silencing activates the AMPK/mTOR pathway, inducing p62‐mediated selective autophagic degradation of YBX1.
Xueqiang Guo, Lingling Xi, Yukun Liu, Wenbao Lv, Tianzi Li, Andong Ju, Zhenlin Fan, Yaping Shen, Zhuang Qian, Weiyun Wang, Zhuo Liang, Wenjuan Song, Kaiwen Chang, Shuangping Ma, Junhe Zhang, Tao Han, Kun You, Cunshuan Xu, Lei Wang, Weisheng Guo, Wenjie Ren   +20 more
wiley   +1 more source

Placenta-derived extracellular vesicles in maternal plasma of Hb Bart's fetuses. [PDF]

Sci Rep
Chaemsaithong P, Warintaksa P, Ruangvutilert P, Luewan S, Phatihattakorn C, Raungrongmorakot K, Chaiyasit N, Tachjaree TP, Prakobpanich M, Panachan J, Kunsawat T, Chiangjong W, Chutipongtanate S.   +12 more
europepmc   +1 more source

Efficacy of the Full Mesenchymal Stromal Cell Secretome versus Purified Small Extracellular Vesicles in Preclinical Models of Erectile Dysfunction: A Systematic Review and Parallel Meta-Analysis

Victor Jeremia Syaropi Simanjuntak, Ishak Andreas Soritua Lumban Gaol, Erlangga Pradipta H, Dimas Sindhu Wibisono   +3 more
openalex   +2 more sources

A Hydrodynamic Bioreactor for High‐Yield Production of Extracellular Vesicles from Stem Cell Spheroids with Defined Cargo Profiling

Advanced Science, EarlyView.
This study harnesses hydrodynamic flows to generate, confine and stimulate stem cell spheroids, enabling the large‐scale production of extracellular vesicles (EVs). This innovative method not only streamlines spheroid formation and subsequent EV release in a single, integrated process, but also ensures the generation of EVs with enhanced biological ...
Solène Lenoir, Elliot Thouvenot, Giacomo Gropplero, Léonie Dec, Damarys Loew, Clotilde Théry, Jose E Perez, Claire Wilhelm   +7 more
wiley   +1 more source

Regenerative Potential of Extracellular Vesicles on Intervertebral Disc Degeneration: What is the EV-idence? [PDF]

JOR Spine
Corraini D, Voskamp C, Wauben MHM, Tryfonidou MA.   +3 more
europepmc   +1 more source