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Protoplasma, 2019
Exocytosis is a key mechanism for delivering materials into the extracellular space for cell function and communication. In plant cells, conventional protein secretion (CPS) is achieved via an ER (endoplasmic reticulum)-Golgi-TGN (trans-Golgi network)-PM (plasma membrane) pathway.
Yong, Cui +3 more
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Exocytosis is a key mechanism for delivering materials into the extracellular space for cell function and communication. In plant cells, conventional protein secretion (CPS) is achieved via an ER (endoplasmic reticulum)-Golgi-TGN (trans-Golgi network)-PM (plasma membrane) pathway.
Yong, Cui +3 more
openaire +2 more sources
Extracellular Vesicles in Chemoresistance
2021Chemotherapy represents the current mainstay therapeutic approach for most types of cancer. Despite the development of targeted chemotherapeutic strategies, the efficacy of anti-cancer drugs is severely limited by the development of drug resistance. Multidrug resistance (MDR) consists of the simultaneous resistance to various unrelated cytotoxic drugs ...
Gabriele, De Rubis, Mary, Bebawy
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Biogenesis of Extracellular Vesicles
2021Extracellular vesicles (EVs) refer to vesicles that are released by cells into the extracellular space. EVs mediate cell-to-cell communication via delivery of functional biomolecules between host and recipient cells. EVs can be categorised based on their mode of biogenesis and secretion and include apoptotic bodies, ectosomes or shedding microvesicles ...
Taeyoung, Kang +2 more
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Extracellular Vesicles and Glycosylation
2021Extracellular vesicles (EVs), a generic term for any vesicles or particles that are released from cells, play an important role in modulating numerous biological and pathological events, including development, differentiation, aging, thrombus formation, immune responses, neurodegenerative diseases, and tumor progression.
Yoichiro, Harada +4 more
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Extracellular Vesicle and Lipoprotein Interactions
Nano Letters, 2023Extracellular vesicles and lipoproteins are lipid-based biological nanoparticles that play important roles in (patho)physiology. Recent evidence suggests that extracellular vesicles and lipoproteins can interact to form functional complexes. Such complexes have been observed in biofluids from healthy human donors and in various in vitro disease models ...
Raluca E. Ghebosu +2 more
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Extracellular vesicles for the delivery of gene therapy
Nature Reviews BioengineeringGene therapy has brought hope for the treatment of previously incurable diseases, such as genetic disorders, cancers and autoimmune diseases. However, gene therapy requires efficient delivery with cell and tissue specificity, which remains challenging ...
Emilio Di Ianni +3 more
semanticscholar +1 more source
Extracellular vesicles in atherosclerosis
Clinica Chimica Acta, 2019Extracellular vesicles (EVs), which exist in human blood, are increased in some inflammation-related cardiovascular diseases. EVs are involved in inflammation, immunity, signal transduction, cell survival and apoptosis, angiogenesis, thrombosis, and autophagy, all of which are highly significant for maintaining homeostasis and disease progression ...
WenYi Deng +6 more
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Extracellular vesicles in leukemia
Leukemia Research, 2018Extracellular vesicles (EV) are nano-sized membrane enclosed vehicles that are involved in cell-to-cell communication and carry cargo that is representative of the parent cell. Recent studies have highlighted the significant roles leukemia EVs play in tumor progression, and ways in which they can lead to treatment evasion, thus meriting further ...
Alejandro, Pando +3 more
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The biology and function of extracellular vesicles in immune response and immunity
ImmunitySummary Extracellular Vesicles (EVs), such as ectosomes and exosomes, contain DNA, RNA, proteins and are encased in a phospholipid bilayer. EVs provide intralumenal cargo for delivery into the cytoplasm of recipient cells with an impact on the function ...
R. Kalluri
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Extracellular vesicles in plants
Molecular PlantExtracellular vesicles (EVs) are cell released lipid-wrapped nano- to micro-sized particles without self-replication ability. Plant cells secrete EVs (PEVs) during normal developmental stage and in response to external stimuli. Distinct from plant-derived nanoparticles (PDNP), here we narrow the definition of PEVs which are naturally secreted by cells,
Ning-Jing Liu, Li-Pan Hou, Xiao-Ya Chen
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