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Extracellular vesicles and viruses
Viruses are subcellular structures that depend on the host cell to replicate, sharing several characteristics with extracellular vesicles (EVs). EVs act in intercellular communication and the regulation of the immune system and can be exploited by viruses as vehicles for transport and dissemination between cells and organs.Juliana, Fortes +4 more
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Extracellular vesicles in plants
Molecular PlantExtracellular vesicles (EVs) are cell released lipid-wrapped nano- to micro-sized particles without self-replication ability. Plant cells secrete EVs (PEVs) during normal developmental stage and in response to external stimuli. Distinct from plant-derived nanoparticles (PDNP), here we narrow the definition of PEVs which are naturally secreted by cells,
Ning-Jing Liu, Li-Pan Hou, Xiao-Ya Chen
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Extracellular vesicle autoantibodies
Journal of AutoimmunityAutoantibodies are immunoglobulin proteins produced by autoreactive B cells responding to self-antigens. Extracellular vesicles (EVs) are membranous structures released by almost all types of cells and extensively distributed in various biological fluids. Studies have indicated that EVs loaded with self-antigens not only play important roles in antigen
Yan, Hua +3 more
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An immunoassay for urinary extracellular vesicles
American Journal of Physiology-Renal Physiology, 2016Although nanosized urinary extracellular vesicles (uEVs) are increasingly used for biomarker discovery, their isolation currently relies on time-consuming techniques hindering high-throughput application. To navigate this problem, we designed an immunoassay to isolate, quantify, and normalize uEV proteins.
Salih, Mahdi +7 more
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Extracellular vesicles: Specialized bone messengers
Archives of Biochemistry and Biophysics, 2014Mammalian cells actively secrete factors that contribute to shape their microenvironment. These factors either travel freely or they are enclosed within the lipid bilayer of extracellular vesicles (EVs), and regulate the function of neighboring and distant cells.
Jess Morhayim +2 more
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RNA delivery by extracellular vesicles in mammalian cells and its applications
Nature Reviews Molecular Cell Biology, 2020Xandra O. Breakefield +2 more
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Extracellular Vesicle and Particle Biomarkers Define Multiple Human Cancers
Cell, 2020Charles Rudin +2 more
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