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Role of Extracellular Vesicle Surface Proteins in the Pharmacokinetics of Extracellular Vesicles
Molecular Pharmaceutics, 2018Extracellular vesicles (EVs) are small membrane vesicles secreted from cells and have great potential as drug delivery carriers. Surface proteins on EV membranes might play roles in pharmacokinetics. One method which can be used to study the role of surface membrane of EV is to modify the inner space of EV.
Chonlada Charoenviriyakul +4 more
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From intra- to extracellular vesicles: extracellular vesicles in developmental signalling
Essays in Biochemistry, 2018Signalling from cell-to-cell is fundamental for determining differentiation and patterning. This communication can occur between adjacent and distant cells. Extracellular vesicles (EVs) are membrane-based structures thought to facilitate the long-distance movement of signalling molecules. EVs have recently been found to allow the transport of two major
Gradilla, Ana-Citlali +3 more
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Extracellular vesicle autoantibodies
Journal of AutoimmunityAutoantibodies are immunoglobulin proteins produced by autoreactive B cells responding to self-antigens. Extracellular vesicles (EVs) are membranous structures released by almost all types of cells and extensively distributed in various biological fluids. Studies have indicated that EVs loaded with self-antigens not only play important roles in antigen
Yan, Hua +3 more
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An immunoassay for urinary extracellular vesicles
American Journal of Physiology-Renal Physiology, 2016Although nanosized urinary extracellular vesicles (uEVs) are increasingly used for biomarker discovery, their isolation currently relies on time-consuming techniques hindering high-throughput application. To navigate this problem, we designed an immunoassay to isolate, quantify, and normalize uEV proteins.
Salih, Mahdi +7 more
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Extracellular vesicles: Specialized bone messengers
Archives of Biochemistry and Biophysics, 2014Mammalian cells actively secrete factors that contribute to shape their microenvironment. These factors either travel freely or they are enclosed within the lipid bilayer of extracellular vesicles (EVs), and regulate the function of neighboring and distant cells.
Jess Morhayim +2 more
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Extracellular vesicles and viruses
Viruses are subcellular structures that depend on the host cell to replicate, sharing several characteristics with extracellular vesicles (EVs). EVs act in intercellular communication and the regulation of the immune system and can be exploited by viruses as vehicles for transport and dissemination between cells and organs.Juliana, Fortes +4 more
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Challenges and directions in studying cell–cell communication by extracellular vesicles
Nature reviews. Molecular cell biology, 2022Guillaume van Niel +5 more
semanticscholar +1 more source
Biogenesis, secretion, and intercellular interactions of exosomes and other extracellular vesicles.
Annual Review of Cell and Developmental Biology, 2014Marina Colombo, G. Raposo, C. Théry
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