Results 131 to 140 of about 859,861 (224)

EV‐SPEC: Decoding the Spatial Proteomic Signature of the Extracellular Vesicle Corona

Journal of Extracellular Biology
ABSTRACT The concept of protein corona formation around extracellular vesicles (EVs) has given birth to new insights into how cells may recognize EVs by proteins presented at the EV surface. Here we present spatially resolved proteomics using the biotin ligase TurboID to map proteins interacting at the EV surface, without a need for ...
Camille Menaceur Vandenbroucke, Carsten Scavenius, Yuya Hayashi   +2 more
openaire   +1 more source

Systematic compositional analysis of exosomal extracellular vesicles produced by cells undergoing apoptosis, necroptosis and ferroptosis

, 2023
Formation of extracellular vesicles (EVs) has emerged as a novel paradigm in cell-to-cell communication in health and disease. EVs are notably produced during cell death but it had remained unclear whether different modalities of regulated cell death ...
Xie, WeiWE148020037431250000-0001-5554-2075ccf09246-dab7-11eb-9e9a-973f3d3bef9b, Hendrix, AnGE380020003830058010020440300000-0002-1883-8309F7EB1496-F0ED-11E1-A9DE-61C894A0A6B4, Cappe, Benjamin0001407278028020019040649726836114940000-0002-8162-9788F619163E-32EC-11E4-9DAC-2B5CB5D1D7B1, Vadi, MikeWE140002004877818020035469032f22bf32-01d6-11eb-bcbd-baa5996c31d1, Lafontaine, Denis L J, Sack, Eliza, Dufour, SaraGE310001308443108020029377220000-0003-2036-7849AF89131E-1A64-11E3-9927-3CD110BDE39D, Vandenabeele, PeterCA05WE140019790145118010005653840000-0002-6669-8822F4243658-F0ED-11E1-A9DE-61C894A0A6B4, Wacheul, Ludivine, Riquet, FranckUGent80200162347197963741600482492F7E-2AE5-11E3-A4E0-796A10BDE39D, Impens, FrancisGE310020011920448010020434240000-0003-2886-9616F7EA3B2A-F0ED-11E1-A9DE-61C894A0A6B4, Verstraeten, BrunoWE140001102355478020023960370000-0003-3573-146338197030-F0EE-11E1-A9DE-61C894A0A6B4, Franck, Julien   +12 more
core  

Extracellular Vesicles (EVs) as "A Window to the Brain": Potential, Challenges and Future Perspectives. [PDF]

Indian J Clin Biochem, 2023
Mitra P, Gupta S, Sharma P.
europepmc   +1 more source

Extracellular vesicles as the next‐generation modulators of pharmacokinetics and pharmacodynamics of medications and their potential as adjuvant therapeutics

Clinical and Translational Medicine
Background and main body Pharmacokinetics (PK) and pharmacodynamics (PD) are central concepts to guide the dosage and administration of drug therapies and are essential to consider for both healthcare professionals and researchers in therapeutic planning
Jiaqi Liu, Joel Z. Nordin, Andrew J. McLachlan, Wojciech Chrzanowski   +3 more
doaj   +1 more source

Playing pin‐the‐tail‐on‐the‐protein in extracellular vesicle (EV) proteomics

PROTEOMICS
AbstractExtracellular vesicles (EVs) are anucleate particles enclosed by a lipid bilayer that are released from cells via exocytosis or direct budding from the plasma membrane. They contain an array of important molecular cargo such as proteins, nucleic acids, and lipids, and can transfer these cargoes to recipient cells as a means of intercellular ...
openaire   +3 more sources

Revolutionizing Stem Cell Based Therapy: The Autostem Platform for Scalable Production of Therapeutic Extracellular Vesicles

Stem cell-based therapies offer promising approaches for the treatment of degenerative and tumor-related diseases. The "RauPE" project (Robust Automated Production of Therapeutically Usable Extracellular Vesicles) is developing a platform for the ...
Milfreit, Tim, Giebel, Bernd, Nießing, Bastian, Milfeit, Tim, Janning, Kai, Carvalho Oliveira, Marco, Heuvel, Yasemin van, van Heuvel, Yasemin, Bongartz, Patrick, Herbst, Laura, Felser, Anna-Lena, Meyer, Moritz, Kutzner, Tanja Jasmin, Schmitt, Robert H.   +13 more
core   +1 more source

Extracellular Vesicles (EVs) as Crucial Mediators of Cell-Cell Interaction in Asthma. [PDF]

Int J Mol Sci, 2023
Tinè M, Padrin Y, Bonato M, Semenzato U, Bazzan E, Conti M, Saetta M, Turato G, Baraldo S.   +8 more
europepmc   +1 more source

Targeted delivery of peptidoglycan hydrolases (PGH) via engineered extracellular vesicles (EVs) to clear intracellular bacterial infections. [PDF]

Mater Today Bio
Sabani B, Leone M, Gasser L, Sumrall E, Meile S, Inderbitzin J, Razansky D, Schmelcher M, Loessner MJ, Riedl R, Lehmann S.   +10 more
europepmc   +1 more source

Editorial: Role of extracellular vesicles (EVs) in pathogenesis, diagnosis, therapeutic delivery, treatment and theranostic applications in cancer. [PDF]

Front Bioeng Biotechnol, 2023
Shahbazi R, Kalishwaralal K, Paul MK, Anto RJ.   +3 more
europepmc   +1 more source

Region-Specific Proteomic Profiles of Extracellular Vesicles (EVs) Derived from Human Macular and Peripheral RPE-Choroid Explants. [PDF]

Biomedicines
Zeng J, Zhang J, Schulz J, Arafah ADB, Lee S, Yam M, Shen Y, Zhou F, Zhang T, Gillies MC, Zhu L.   +10 more
europepmc   +1 more source