Results 121 to 130 of about 859,861 (224)

In vitro decidualisation of human endometrial stromal cells is enhanced by seminal fluid extracellular vesicles

Journal of Extracellular Vesicles, 2019
Extracellular vesicles are highly abundant in seminal fluids and have a known role enhancing sperm function. Clinical pregnancy rates after IVF treatment are improved after female exposure to seminal fluid.
Helena Rodriguez-Caro, Rebecca Dragovic, Mengni Shen, Eszter Dombi, Ginny Mounce, Kate Field, Jamie Meadows, Karen Turner, Daniel Lunn, Tim Child, Jennifer Helen Southcombe, Ingrid Granne   +11 more
doaj   +1 more source

Extracellular vesicles containing oncogenic mutant β-catenin activate Wnt signalling pathway in the recipient cells

, 2019
Mutations in β-catenin, especially at the residues critical for its degradation, render it constitutively active. Here, we show that mutant β-catenin can be transported via extracellular vesicles (EVs) and activate Wnt signalling pathway in the recipient
Liem, M, Fonseka, P, Samuel, M,, Gangoda, L, Keerthikumar, S, Collins, C, Kalra, H, Boukouris, S, Al, Saffar H, Chitti, SV   +9 more
core   +1 more source

Extracellular Vesicles and Immunity: At the Crossroads of Cell Communication

International Journal of Molecular Sciences
Extracellular vesicles (EVs), comprising exosomes and microvesicles, are small membranous structures secreted by nearly all cell types. They have emerged as crucial mediators in intercellular communication, playing pivotal roles in diverse physiological ...
Noemi Aloi, G. Drago, S. Ruggieri, Fabio Cibella, Paolo Colombo, Valeria Longo   +5 more
semanticscholar   +1 more source

Extracellular Vesicle (EV) Survivin for Cancer Diagnostics and Therapeutics: A Review

Frontiers in Bioscience-Landmark
Survivin, an important inhibitor of apoptosis protein, contributes to cancer cells’ resistance to apoptosis, proliferation, and survival. It is a promising biomarker and therapeutic target due to being highly expressed in cancer cells relative to normal cells and universally expressed in almost all cancer types.
Shisong Jiang, Su Myat Phyu, Wynne Wijaya   +2 more
openaire   +3 more sources

The role of Extracellular Vesicles (EVs) in Amyotrophic Lateral Sclerosis (ALS) and Frontotemporal Lobar Degeneration (FTLD)

, 2021
ALS and FTLD are neurodegenerative diseases characterized by pathological ubiquitinated and phosphorilated inclusions in the cytosol of affected cells. In 98% of ALS and in the majority of Tau-negative FTLD cases the main component is the TAR DNA-binding
Fabrizio Fabbiano, Angelo Poletti, Maria Cristina Gagliani, Mariarita Galbiati, Cristina Cereda, Stella Gagliardi, Eleonora Corridori, Marta Chierichetti, Elena Casarotto, Daisy Sproviero, Katia Cortese, Paola Rusmini, Marta Cozzi, Barbara Tedesco, Veronica Ferrari, Vito D'agostino, Riccardo Cristofani, Valeria Crippa   +17 more
core   +1 more source

Marine Delivery Vehicles: Molecular Components and Applications of Bacterial Extracellular Vesicles

Marine Drugs
In marine ecosystems, communication among microorganisms is crucial since the distance is significant if considered on a microbial scale. One of the ways to reduce this gap is through the production of extracellular vesicles, which can transport ...
Angela Casillo, Raffaele D’Amico, Rosa Lanzetta, Maria Michela Corsaro   +3 more
doaj   +1 more source

The role and applications of extracellular vesicles in osteoporosis

Bone Research
Osteoporosis is a widely observed condition characterized by the systemic deterioration of bone mass and microarchitecture, which increases patient susceptibility to fragile fractures. The intricate mechanisms governing bone homeostasis are substantially
Fei Fang, Jie Yang, Jia-He Wang, Tiantian Li, Er-Xiang Wang, De-Mao Zhang, Xiao-Heng Liu, Chenchen Zhou   +7 more
semanticscholar   +1 more source

Transfer of inflammatory mitochondria via extracellular vesicles from M1 macrophages induces ferroptosis of pancreatic beta cells in acute pancreatitis

Journal of Extracellular Vesicles
Extracellular vesicles (EVs) exert a significant influence not only on the pathogenesis of diseases but also on their therapeutic interventions, contingent upon the variances observed in their originating cells.
Yu-Hua Gao, Ningning Mi, Wenxian Wu, Yuxuan Zhao, Fangzhou Fan, Wangwei Liao, Yongliang Ming, Weijun Guan, Chunyu Bai   +8 more
semanticscholar   +1 more source

Engineered extracellular vesicles for tissue repair and regeneration

Burns & Trauma
Extracellular vesicles (EVs) are heterogeneous membrane-like vesicles secreted by living cells that are involved in many physiological and pathological processes and act as intermediaries of intercellular communication and molecular transfer.
Yan Zhang, Dan Wu, Chen Zhou, Mu-Ran Bai, Yu-Cheng Wan, Qing Zheng, Zhijin Fan, Xian-Wen Wang, Chun Yang   +8 more
semanticscholar   +1 more source

Quantitative Analysis of Complement Membrane Attack Complex Proteins Associated with Extracellular Vesicles

Extracellular vesicles (EVs) represent a universal mechanism of intercellular communication in normal and pathological conditions. There are reports showing the presence of complement proteins in EV preparations, specifically those that can form a ...
Illarion V. Turko
core   +1 more source