Results 101 to 110 of about 859,861 (224)

Minimal experimental requirements for definition of extracellular vesicles and their functions: a position statement from the International Society for Extracellular Vesicles [PDF]

, 2014
Secreted membrane-enclosed vesicles, collectively called extracellular vesicles (EVs), which include exosomes, ectosomes, microvesicles, microparticles, apoptotic bodies and other EV subsets, encompass a very rapidly growing scientific field in biology ...
Sahoo, S, Di Vizio, Dolores, Wauben, MH, Witwer, KW, Buzás, Edit I, Yong Song Gho, Vizio, DD, Mathivanan, S, Wauben, Marca H, Sahoo, Susmita, Igor V. Kurochkin, Fred Hochberg, Gho, YS, Lötvall, J, Lötvall, Jan,, Lötvall, Jan, Witwer, Kenneth W, Théry, Clotilde, B&C BRC-SIB, Hidetoshi Tahara, Strategic Infection Biology, Kenneth W. Witwer, Kurochkin, IV, Marca H. Wauben, Kurochkin, Igor V, LS Celbiologie-Algemeen, Hochberg, F, Gardiner, C, Mathivanan, Suresh, Hochberg, Fred, Dolores Di Vizio, Gho, Yong Song, Buzás, EI, Gardiner, Christopher, Edit I. Buzás, Christopher Gardiner, Biology of Reproductive Cells, Tahara, Hidetoshi, Hill, Andrew F, Andrew F. Hill, Peter Quesenberry, Susmita Sahoo, Quesenberry, Peter, Hill, AF, Quesenberry, P, Théry, C, Gho, Yong Song,, Di Vizio, D, Jan Lötvall, Tahara, H, Suresh Mathivanan, Clotilde Théry   +51 more
core   +1 more source

Application potential of stem/progenitor cell-derived extracellular vesicles in renal diseases

Stem Cell Research & Therapy, 2019
Extracellular vesicles (EVs) are nanometer-sized and membrane-bound vesicles, including exosomes and microvesicles. EVs can deliver bioactive macromolecules such as proteins, lipids, and nucleic acids, allowing intercellular communication in ...
Xiao Sun, Huanyu Meng, Wuqing Wan, Min Xie, Chuan Wen   +4 more
doaj   +1 more source

Isolation and analysis methods of extracellular vesicles (EVs)

, 2021
Extracellular vesicles (EVs) have been recognized as an evolving biomarker within the liquid biopsy family. While carrying both host cell proteins and different types of RNAs, EVs are also present in sufficient quantities in biological samples to be ...
Wijerathne, Harshani, Soper, Steven A., Godwin, Andrew K., Zhao, Zheng   +3 more
core  

Metabolomics Applied to the Study of Extracellular Vesicles [PDF]

, 2019
Cell-secreted extracellular vesicles (EVs) have rapidly gained prominence as sources of biomarkers for non-invasive biopsies, owing to their ubiquity across human biofluids and physiological stability.
Charles Williams, Siljander, Pia R-M, Siljander, Pia R.-M., Juan M. Falcón-Pérez, Reichardt, Niels-Christian, Niels-Christian Reichardt, Williams, Charles, Palviainen, Mari, Falcon-Perez, Juan M., Mari Palviainen, Pia R.-M. Siljander   +10 more
core   +1 more source

Dual roles of the conditional extracellular vesicles derived from Pseudomonas aeruginosa biofilms: Promoting and inhibiting bacterial biofilm growth

Biofilm
Antibiotic-resistant biofilm infections have emerged as public health concerns because of their enhanced tolerance to high-dose antibiotic treatments. The biofilm life cycle involves multiple developmental stages, which are tightly regulated by active ...
Marwa Gamal Saad, Haluk Beyenal, Wen-Ji Dong   +2 more
doaj   +1 more source

The Emerging Roles of Extracellular Vesicles in Osteosarcoma

Frontiers in Oncology, 2019
Extracellular vesicles (EVs) are heterogeneous nanosized vesicles that are constitutively released by virtually all types of cells. They have been isolated in almost all body fluids.
Francesca Perut, Laura Roncuzzi, Nicola Baldini, Nicola Baldini   +3 more
doaj   +1 more source

Immunogenicity of Extracellular Vesicles

Advances in Materials
Extracellular vesicles (EVs) are promising next‐generation therapeutics and drug delivery systems due to demonstrated safety and efficacy in preclinical models and early‐stage clinical trials. There is an urgent need to address the immunogenicity of EVs (
Yutian Xia, Jianzhong Zhang, Gang Liu, Joy Wolfram   +3 more
semanticscholar   +1 more source

Different storage and freezing protocols for extracellular vesicles: a systematic review

Stem cell research & therapeutics
Extracellular vesicles (EVs) have been considered promising tools in regenerative medicine. However, the nanoscale properties of EVs make them sensitive to environmental conditions.
Shahin Ahmadian, Negin Jafari, A. Tamadon, A. Ghaffarzadeh, R. Rahbarghazi, Mahdi Mahdipour   +5 more
semanticscholar   +1 more source

Quality and Safety Considerations for Therapeutic Products Based on Extracellular Vesicles

Pharmaceutical Research
Extracellular vesicles (EVs) serve as an intrinsic system for delivering functional molecules within our body, playing significant roles in diverse physiological phenomena and diseases.
Y. Takakura, R. Hanayama, Kazunari Akiyoshi, S. Futaki, Kyoko Hida, T. Ichiki, Akiko Ishii-Watabe, M. Kuroda, Kazushige Maki, Yasuo Miura, Y. Okada, N. Seo, T. Takeuchi, Teruhide Yamaguchi, Y. Yoshioka   +14 more
semanticscholar   +1 more source

Cellular uptake and in vivo distribution of mesenchymal-stem-cell-derived extracellular vesicles are protein corona dependent

Nature Nanotechnology
Extracellular vesicles (EVs) derived from mesenchymal stem cells are promising nanotherapeutics in liver diseases due to their regenerative and immunomodulatory properties.
Revadee Liam-or, F. Faruqu, A. Walters, Shunping Han, Li-Zhou Xu, J. Wang, Jennifer Oberlaender, A. Sánchez-Fueyo, Giovanna Lombardi, F. Dazzi, V. Mailänder, K. Al-Jamal   +11 more
semanticscholar   +1 more source