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Signal amplification strategies in biosensing of extracellular vesicles (EVs)

Talanta, 2023
Extracellular vesicles (EVs) are membrane-enclosed vesicles secreted from mammalian cells. EVs act as multicomponent delivery vehicles to carry a wide variety of biological molecular information and participate in intercellular communications. Since elevated levels of EVs are associated with some pathological states such as inflammatory diseases and ...
Khalil Abnous   +2 more
exaly   +3 more sources

Biological function of Extracellular Vesicles (EVs): a review of the field

Molecular Biology Reports, 2023
Extracellular vesicles (EVs) theranostic potential is under intense investigation. There is a wealth of information highlighting the role that EVs and the secretome play in disease and how these are being utilized for clinical trials and novel therapeutic possibilities.
Arezoo Mohammadipoor   +8 more
openaire   +2 more sources

Isolation and Purification of Mycobacterial Extracellular Vesicles (EVs)

2023
Bacterial extracellular vesicles (EVs) contain numerous active substances that mediate bacterial interactions with their host and with other microbes. Best defined are the EVs from Gram-negative bacteria that have been shown to deliver virulence factors, modulate the immune responses, mediate antibiotic resistance, and also inhibit competitive microbes.
Komal Umashankar, Rao, Gabriela, Godaly
openaire   +2 more sources

Characterization of GPCRs in extracellular vesicle (EV)

2017
Extracellular vesicle (EV) are tiny membranous vesicles usually
Manoj R, Medapati   +6 more
openaire   +2 more sources

Extracellular Vesicle (EV) Dot Blotting for Multiplexed EV Protein Detection in Complex Biofluids

Analytical Chemistry, 2022
Extracellular vesicles (EVs) are nanoscale vesicles secreted from cells, carrying biomolecular cargos similar to their cells of origin. Measuring the protein content of EVs in biofluids can offer a crucial insight into human health and disease. For example, detecting tumor-derived EVs' protein markers can aid in early diagnosis of cancer, which is life-
Nikan Momenbeitollahi   +4 more
openaire   +2 more sources

Determination of the Procoagulant Activity of Extracellular Vesicle (EV) Using EV-Activated Clotting Time (EV-ACT)

Journal of Visualized Experiments, 2023
The role of extracellular vesicles (EV) in various diseases is gaining increased attention, particularly due to their potent procoagulant activity. However, there is an urgent need for a bedside test to assess the procoagulant activity of EV in clinical settings.
Yalong, Gao   +4 more
openaire   +2 more sources

EVs in the retina: Shining light on extracellular vesicles

Trillium Extracellular Vesicles, 2023
The present review presents the current knowledge on extracellular vesicle biology in the retina, a highly structured part of the central nervous system that is at the same time easily accessible. Numbers of publications in the field are rapidly rising, but most studies focus on extracellular vesicles as biomarkers for retinal diseases or as putative ...
openaire   +1 more source

MS-Based Extracellular Vesicle (EVs) Analysis: An Application to Helminth-Secreted EVs

2021
Parasite infections caused by helminths affect hundreds of millions worldwide. Despite their socioeconomic importance and impact on health, there is still an urgent need to develop appropriate control approaches. The recent discovery that helminths, as most eukaryotic organisms, secrete extracellular vesicles (EVs) of different type has opened new ...
openaire   +2 more sources

Extracellular Vesicles (EVs)

2022
Senny Nordmeier   +2 more
openaire   +2 more sources

Association between extracellular vesicles (EVs) and thrombosis in antiphospholipid syndrome

Lupus
Background Antiphospholipid syndrome (APS) is characterized by thrombosis or pregnancy complications associated with the presence of antiphospholipid antibodies (aPLs). Although the exact mechanisms are unclear, aPLs can increase the expression of tissue factor on platelets, leukocytes, and endothelial cells ...
Bruna Cardoso Jacintho-Robison   +7 more
openaire   +2 more sources

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