Results 101 to 110 of about 8,377,419 (215)

Obstacles and opportunities in the functional analysis of extracellular vesicle RNA - An ISEV position paper [PDF]

, 2017
© 2017 The Author(s). The release of RNA-containing extracellular vesicles (EV) into the extracellular milieu has been demonstrated in a multitude of different in vitro cell systems and in a variety of body fluids.
Schiffelers, Raymond M., Mittelbrunn, Maria, Witwer, Kenneth W., Nolte-'t Hoen, Esther N.M., Lässer, Cecilia, Maas, Sybren L.N., Nawaz, Muhammed, Jones, Jennifer C., Lunavat, Taral R., Pegtel, D. Michiel, Lorenowicz, Magdalena J., Pfaffl, Michael W., Tahara, Hidetoshi, Hill, Andrew F., Théry, Clotilde, Van Keuren-Jensen, Kendall R., di Liegro, Italia, Momma, Stefan, Lai, Charles P., Fernández-Messina, Lola, Mukherjee, Kamalika, Haderk, Franziska, Tosar, Juan Pablo, Chow, WN, Mäger, Imre, Wauben, Marca H.M.   +25 more
core   +1 more source

A new flow chip in combination with multiphoton microscopy as a protocol for longitudinal 3D imaging of tissue calcification under shear stress

FEBS Open Bio, EarlyView.
Miniaturized flow chip platform enabling continuous perfusion and longitudinal multiphoton 3D imaging of vascular smooth muscle cell constructs under physiological flow. Brightfield imaging guides region selection, while CellTracker Green and mRuby‐labeled fetuin‐A visualize cells and mineral deposition, respectively. Magnesium supplementation markedly
Vytautas Kučikas, Aaron D. Morgan, Ignas Čiurlionis, Christian Böhm, Stefan Jockenhövel, Willi Jahnen‐Dechent, Marc A. M. J. van Zandvoort   +6 more
wiley   +1 more source

Dual-Layer Spectral Detector Computed Tomography Quantitative Parameters: A Potential Tool for Lymph Node Activity Determination in Lymphoma Patients

Diagnostics
Dual-energy CT has shown promising results in determining tumor characteristics and treatment effectiveness through spectral data by assessing normalized iodine concentration (nIC), normalized effective atomic number (nZeff), normalized electron density (
Hebing Chen, Yuxiang Fang, Jin Gu, Peng Sun, Lian Yang, Feng Pan, Hongying Wu, Tianhe Ye   +7 more
doaj   +1 more source

Dose‐dependent hepatotoxicity of hydrogen peroxide in HepG2 cells and its modulation by CYP450 induction

FEBS Open Bio, EarlyView.
NMR metabolomics revealed concentration‐dependent metabolic perturbations in HepG2 cells exposed to H2O2. Rifampicin pretreatment enhanced metabolic competence, attenuated toxin‐induced alterations and produced metabolite profiles more consistent with human liver physiology, supporting the use of CYP450‐induced HepG2 models for improved in vitro ...
Maren Jinks, Garth L. Maker, Emily C. Davies, Berin A. Boughton, Samantha Lodge   +4 more
wiley   +1 more source

Cardiac risk and myocardial fibrosis assessment with cardiac magnetic resonance in patients with myotonic dystrophy

Frontiers in Neurology
IntroductionNon-invasive evaluation of myocardial tissue is a major goal of cardiac imaging. This is the case of myocardial fibrosis which is crucial in many myocardial diseases.
Elena Abati, Elena Abati, Claudia Alberti, Valentina Tambè, Anastasia Esseridou, Giacomo Pietro Comi, Giacomo Pietro Comi, Stefania Corti, Stefania Corti, Giovanni Meola, Giovanni Meola, Francesco Secchi, Francesco Secchi   +12 more
doaj   +1 more source

Effects of extracellular calcium on normal human bone cells [PDF]

, 2000
P(論文)It has been demonstrated that elevated extracellular calcium can inhibit the formation of osteoclast-like cells and stimulate osteoblastic proliferation, indicating that extracellular calcium is very important for the process of bone remodeling. The
35845, 35844, 35843, 賀来, 亨, 中出, 修, 小山, 宏樹, 高橋, 香苗, 25933   +7 more
core  

KDAC6 alters cell morphology and motility through positive and negative modulation of F‐actin distribution

FEBS Open Bio, EarlyView.
KDAC6 has been associated with cell motility and actin structures, but specific domain contributions are not established. The two catalytic domains have differential effects on motility and F‐actin regulation, affecting cortical F‐actin density, motility, stress fibers, and cell spreading.
Taylor V. Joseph, Andrea B. Pham, Kiara E. Bornes, Razan H. Hammad, Chelsea A. Rousseve‐Ross, Thomas M. Huckaba, Terry J. Watt, Tasha B. Toro   +7 more
wiley   +1 more source

Combined CT-based extracellular volume with pathologic indicators predicts early postoperative recurrence of gastric mesenchymal tumors

陆军军医大学学报
Objective To investigate the clinical value of extracellular volume (ECV) based on CT delayed phase in combination with pathologic indicators in predicting early recurrence of gastric mesenchymal tumors after surgery. Methods A retrospective case-control
LU Hong, LU Hong, LI Haitao, CAI Ping
doaj   +1 more source

Accurate and noninvasive prostate cancer detection using plasma‐derived extracellular vesicle RNA

FEBS Open Bio, EarlyView.
Plasma extracellular vesicles were captured with WGA‐conjugated magnetic beads and profiled for RNA biomarkers. A three‐RNA panel (NM_024955, NR_047469, and NR_002564) distinguished prostate cancer from healthy controls and benign prostatic hyperplasia, supporting a simple, noninvasive approach to improve prostate cancer detection.
Hanping Wei, Haoran Wu, Wei Feng
wiley   +1 more source

Excellent Reproducibility of Synthetic Extracellular Volume Without Blood Extraction Across Different Cardiomyopathies Using Published Regression Models

Journal of Cardiovascular Development and Disease
T1 mapping and extracellular volume (ECV) calculations in cardiac magnetic resonance (CMR) have the potential to identify early fibrosis that is not yet visible using late gadolinium enhancement; however, the need for same-day blood draws due to the ...
Jeong W. Choi, Sylvia Biso, Jonathan Weber, Karli Pipitone, Shibu Philip, Omar K. Khalique   +5 more
doaj   +1 more source