Results 51 to 60 of about 8,377,419 (215)

Wakefulness affects synaptic and network activity by increasing extracellular astrocyte-derived adenosine [PDF]

, 2012
Loss of sleep causes an increase in sleep drive and deficits in hippocampal-dependent memory. Both of these responses are thought to require activation of adenosine A1 receptors (adorA1Rs) and release of transmitter molecules including ATP, which is ...
Schmitt, L. Ian, R. E. Sims, Sims, Robert E., P. G. Haydon, Dale, Nicholas, Sims, Robert, Haydon, Philip G, L. I. Schmitt, N. Dale, Schmitt, L Ian   +9 more
core   +1 more source

Metastatic niche shaped by host factors influences disseminated cancer cell fate

FEBS Letters, EarlyView.
Metastasis is shaped not only by cancer cells but also by the environments they encounter. This review explores how factors such as aging, diet, the microbiome, lifestyle, and environmental exposures remodel organ‐specific niches in the lung, liver, bone, and brain, influencing where metastatic cells survive, remain dormant, or grow, and ultimately ...
Gwennan Delyth Ward, Álvaro Ruiz‐Tabas, Patricia Altea‐Manzano   +2 more
wiley   +1 more source

Epicardial Adipose Tissue and Left Ventricular Hypertrophy in Hypertensive Patients With Preserved Ejection Fraction: A Multicenter Retrospective Cohort Study

The Journal of Clinical Hypertension
This study aimed to investigate the correlation of the increased volume index of epicardial adipose tissue (EAT) and left ventricular hypertrophy (LVH) in patients with Hypertension (HTN).
Runze Zhu, Wenxian Wang, Yan Gao, Junchuan Liu, Bowen Li, Rongxue Shan, Runjie Xue, Xianshun Yuan, Xi‐Ming Wang   +8 more
doaj   +1 more source

Lysyl oxidase (LOX)‐mediated remodeling of the extracellular matrix

FEBS Letters, EarlyView.
The lysyl oxidase (LOX) family of enzymes drives extracellular matrix remodeling by oxidizing collagen, elastin, and fibronectin, promoting covalent cross‐link formation. This activity regulates tissue architecture and mechanical properties, while its dysregulation contributes to fibrosis, cardiovascular disease, glaucoma, connective tissue disorders ...
Fernando Rodríguez‐Pascual, Marta Navarro‐Gutiérrez, Verónica Romero‐Albillo, Raquel Jiménez‐Sánchez   +3 more
wiley   +1 more source

Cardiac magnetic resonance biomarkers for cardiovascular complications in diabetes: a systematic review and meta-analysis

Frontiers in Cardiovascular Medicine
BackgroundCardiovascular disease (CVD) is the leading cause of morbidity and mortality in diabetes mellitus (DM). Cardiac magnetic resonance (CMR) biomarkers, such as T1 mapping, extracellular volume fraction (ECV), and perfusion indices, have emerged as
Ning Li, Jitao Zhang, Yongyan Wang, Yugeng Li   +3 more
doaj   +1 more source

Membrane composition and thermodynamic identity as boundaries of life for synthetic cell research

FEBS Letters, EarlyView.
What makes a cell a cell? The boundary of a living cell is not just a wall. Read as a Markov blanket, the membrane separates internal from external states, generating identity and non‐equilibrium order. Can this identity be rebuilt from scratch in a synthetic cell?
Caterina Presutti, Bert Poolman
wiley   +1 more source

Computed Tomography-Derived Left Ventricular Extracellular Volume Predicts Reverse Remodeling After Catheter Ablation for Atrial Fibrillation

Journal of Cardiovascular Development and Disease
Left ventricular (LV) extracellular volume fraction (ECV) quantified by cardiac computed tomography (CT) reflects diffuse myocardial fibrosis. In patients with atrial fibrillation (AF) and reduced LV ejection fraction (LVEF), distinguishing tachycardia ...
Makiko Kinoshita, Hiroyuki Takaoka, Yusei Nishikawa, Yoshitada Noguchi, Katsuya Suzuki, Shuhei Aoki, Satomi Yashima, Kazuki Yoshida, Haruka Sasaki, Noriko Suzuki-Eguchi, Tomonori Kanaeda, Yusuke Kondo, Yoshio Kobayashi   +12 more
doaj   +1 more source

EVpedia: an integrated database of high-throughput data for systemic analyses of extracellular vesicles.

, 2018
11111scopu
Sae Rom Kim, Jaewook Lee, Dae-Kyum Kim, Eun-Jeong Choi, Byeongsoo Kang, Gyeongyun Go, Su Chul Jang, Yong Song Gho, Dong-sic Choi, Ji Hyun Kim, Yae Jin Yoon, Kyong-Su Park, Kwang Pyo Kim, Daehee Hwang, Jan Lo¨ tvall, Dominic M. Desiderio, Oh Youn Kim, Yoon-Keun Kim   +17 more
core   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Cardiac Magnetic Resonance Findings and NT-proBNP in Heart Failure with Reduced Ejection Fraction

Tomography
Background/Objectives: N-terminal pro-B-type natriuretic peptide (NT-proBNP) is an established heart failure biomarker, but its associations with cardiac magnetic resonance (CMR) parameters in patients with reduced ejection fraction remain unclear.
Kemal Bugra Memis, İffet Doğan, Defne Şahin, Ali Osman Gulmez, Ece Özer, Mecit Kantarci   +5 more
doaj   +1 more source