Results 121 to 130 of about 190,111 (180)

Extrachromosomal inheritance of paromomycin resistance in Saccharomyces cerevisiae

open access: closedMolecular and General Genetics MGG, 1973
In Saccharomyces cerevisiae, mutants were isolated which show high resistance to the aminoglycoside paromomycin. Amino acid incorporation of mitochondria isolated from such mutant strains proved also to be paromomycin resistant. All of them are cross-resistant to the structurally related antibiotic neomycin.
Regina Kutzleb   +2 more
semanticscholar   +5 more sources

EVIDENCE OF EXTRACHROMOSOMAL INHERITANCE IN CHENOPODIUM RUBRUM

open access: closedCanadian Journal of Genetics and Cytology, 1968
A curled-leaf mutation (Cu) was induced in Chenopodium rubrum by diethyl sulphate treatment and reversed in high frequency (21.5%) by X-rays. Nonchromosomal inheritance is demonstrated for the Cu mutation. Evidence for nonchromosomal inheritance is based
Beatrice E. Murray, Iris L. Craig
semanticscholar   +4 more sources

Extrachromosomal inheritance of nalidixic acid resistance in the petite negative yeast Schizosaccharomyces pombe

open access: closedMolecular and General Genetics MGG, 1982
Spontaneous mutants resistant to nalidixic acid (NAL) were isolated from the petite negative yeast Schizosaccharomyces pombe (S. pombe). One of these mutants, resistant to 200 micrograms/ml NAL, nalr-Y13, was characterized both genetically and biochemically.
Domenica Rita Massardo   +3 more
semanticscholar   +5 more sources

Abstract 2564: Tracing extrachromosomal DNA inheritance patterns in glioblastoma using CRISPR

open access: closedCancer Research, 2019
Glioblastoma (GBM) is the most lethal brain tumor; it is characterized by poor response to standard post-resection radiation and cytotoxic therapy, resulting in a dismal prognosis with a five-year survival rate of 10%. Recurrence after therapy for GBM is
Eunhee Yi, Roel G.W. Verhaak
semanticscholar   +4 more sources

Extrachromosomal inheritance of susceptibility to trypanosome infection in tsetse flies

open access: closedAnnals of Tropical Medicine & Parasitology, 1985
Differences in susceptibility to infection with Trypanosoma congolense between F1 families of Glossina morsitans morsitans indicated that susceptibility is maternally inherited in this species of tsetse fly.
I. Maudlin, Peter P. Dukes
semanticscholar   +5 more sources

Chromosomal and extrachromosomal inheritance of erythromycin-resistance in the “Petite-Negative” yeastKluyveromyces lactis

open access: closedMolecular and General Genetics MGG, 1977
Spontaneously arising erythromycin-resistant mutants were isolated in the "petite-negative" yeast Kluyveromyces lactis. Two independently arising mutants were studied, in one erythromycin-resistance was conferred by a single dominant nuclear gene, and in the other the resistance was extrachromosomally inherited.
Luigi Del Giudice, Aurora Brunner
semanticscholar   +5 more sources

Quantitative models of hybrid dysgenesis: Rapid evolution under transposition, extrachromosomal inheritance, and fertility selection

open access: closedTheoretical Population Biology, 1985
A model of the P-M system of hybrid dysgenesis is presented which incorporates single-site transposition of P factors in M cytotype, determination of offspring cytotype by both maternal cytotype and maternal or offspring nuclear genotype, and strong fertility selection in dysgenic individuals.
Marcy K. Uyenoyama
semanticscholar   +5 more sources

Abstract 3884: Uneven inheritance and functional heterogeneity derived from extrachromosomal DNA enable rapid adaptation of cancer cells

open access: closedCancer Research
The amplification of oncogenes on extrachromosomal DNA (ecDNA) is common in cancer and associated with poor outcomes. Uneven inheritance of ecDNA during cell division leads to intratumoral ecDNA copy number heterogeneity.
Shu Zhang   +10 more
openalex   +2 more sources

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