Results 141 to 150 of about 5,488 (166)

Extrachromosomal inheritance in Schizosaccharomyces pombe

Molecular and General Genetics MGG, 1976
In contrast to the wild-type, mutant [ANTr8] is able spontaneously to throw off stable respiratory deficient mutants. The frequency of these mutants is considerably enhanced by treatment with ethidium bromide (EB) or the azo-dye Janus green (JG). An unstable cell state with a petite-like phenotype is found in both mutant [ANTr8] and wild-type after EB ...
K, Wolf, B, Lang, G, Burger, F, Kaudewitz   +3 more
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Extrachromosomal inheritance in Schizosaccharomyces pombe

Molecular and General Genetics MGG, 1978
Crosses involving mitochondrial markers conferring resistance to antimycin (anar, AR), chloramphenicol (capr, CR), and erythromycin (eryr, ER) in cis- and trans-configuration were studied by zygote clone analysis. Mutant anar-8, from which all other drug--resistant isolates were derived, exhibits a highly biased transmission (6.8% anar) in an analysis ...
G, Seitz-Mayr, K, Wolf, F, Kaudewitz
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Extrachromosomal Inheritance of Drug Resistance and Respiratory Deficiency in the Fission Yeast Schizosaccharomyces pombe

1976
G Bürger, F Kaudewitz
exaly   +2 more sources

Chromosomal and extrachromosomal inheritance of erythromycin-resistance in the “Petite-Negative” yeastKluyveromyces lactis

Molecular and General Genetics MGG, 1977
Spontaneously arising erythromycin-resistant mutants were isolated in the "petite-negative" yeast Kluyveromyces lactis. Two independently arising mutants were studied, in one erythromycin-resistance was conferred by a single dominant nuclear gene, and in the other the resistance was extrachromosomally inherited.
L, Del Giudice, A, Brunner
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EVIDENCE OF EXTRACHROMOSOMAL INHERITANCE INCHENOPODIUM RUBRUM

Canadian Journal of Genetics and Cytology, 1968
A curled-leaf mutation (Cu) was induced in Chenopodium rubrum by diethyl sulphate treatment and reversed in high frequency (21.5%) by X-rays. Nonchromosomal inheritance is demonstrated for the Cu mutation. Evidence for nonchromosomal inheritance is based on mutation frequency; mutagenic specificity, non-Mendelian segregation; and an absence of ...
Beatrice E. Murray, Iris L. Craig
openaire   +1 more source

Extrachromosomal inheritance of nalidixic acid resistance in the petite negative yeast Schizosaccharomyces pombe

Molecular and General Genetics MGG, 1982
Spontaneous mutants resistant to nalidixic acid (NAL) were isolated from the petite negative yeast Schizosaccharomyces pombe (S. pombe). One of these mutants, resistant to 200 micrograms/ml NAL, nalr-Y13, was characterized both genetically and biochemically.
D R, Massardo, L, Del Giudice, F, Manna, K, Wolf   +3 more
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Expression and inheritance of the yeast extrachromosomal element ψ do not depend on RNA polymerase I

Current Genetics, 1994
The extrachromosomal element psi affects translation fidelity in the yeast Saccharomyces cerevisiae by increasing the efficiency of tRNA-mediated ochre suppression. The nature of the psi factor is unknown, although there is evidence that 3-microns circles from psi+ strains can be used to transform psi- cells to psi+.
C R, Nierras, B S, Cox
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Extrachromosomal forms of CLV DNA1 in transgenic plants are inherited by symptom-free progeny

Plant Science, 1989
Abstract Two full length copies of Cassava latent virus (CLV) DNA1 were cloned in head to tail arrangement on a plant expression vector to evaluate the potential of CLV for the development of an extrachromosomal vector system in plants. After direct transfer of the plasmid into protoplasts of Nicotiana tabacum cv.
Peter Meyer, Ingrid Niedenhof, Iris Heidmann, Heinz Saedler   +3 more
openaire   +1 more source

Tethered to survive: Mitotic transcription secures faithful inheritance of extrachromosomal DNA

Molecular Cell
In this issue of Molecular Cell, Nichols et al.1 uncover a transcription-dependent tethering mechanism that enables mitotic inheritance of extrachromosomal DNA (ecDNA) in cancer cells, revealing how transcriptionally active ecDNA escapes degradation and drives oncogene persistence through cell division.
Xue, Jin, Roel G W, Verhaak
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Abstract 2564: Tracing extrachromosomal DNA inheritance patterns in glioblastoma using CRISPR

Cancer Research, 2019
Abstract Glioblastoma (GBM) is the most lethal brain tumor; it is characterized by poor response to standard post-resection radiation and cytotoxic therapy, resulting in a dismal prognosis with a five-year survival rate of 10%. Recurrence after therapy for GBM is unavoidable.
Eunhee Yi, Roel Verhaak
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