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Extracorporeal carbon dioxide removal for acute respiratory failure: a review of potential indications, clinical practice and open research questions [PDF]

Intensive Care Medicine, 2022
International audienceExtracorporeal carbon dioxide removal (ECCO2R) is a form of extracorporeal life support (ECLS) largely aimed at removing carbon dioxide in patients with acute hypoxemic or acute hypercapnic respiratory failure, so as to minimize ...
Daniel Brodie, Alain Combes, Samir Jaber   +2 more
exaly   +2 more sources

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Extracorporeal Carbon Dioxide Removal in the Treatment of Status Asthmaticus

Critical Care Medicine, 2020
Objectives: Venovenous extracorporeal carbon dioxide removal may be lifesaving in the setting of status asthmaticus. Design: Retrospective review. Setting: Medical ICU.
Bianca J, Bromberger, Cara, Agerstrand, Darryl, Abrams, Alexis, Serra, Dana, Apsel, Yuliya, Tipograf, Mark E, Ginsburg, Michael I, Ebright, B Payne, Stanifer, Roy, Oommen, Matthew, Bacchetta, Daniel, Brodie, Joshua R, Sonett   +12 more
openaire   +2 more sources

Enhanced extracorporeal carbon dioxide removal by acidification and metabolic control

Minerva Anestesiologica, 2023
Extracorporeal carbon dioxide removal (ECCO2R) promotes protective ventilation in patients with acute respiratory failure, but devices with high CO2 extraction capacity are required for clinically relevant impact. This study evaluates three novel low-flow techniques based on dialysate acidification, also combined with renal replacement therapy, and ...
Florio, Gaetano, Valsecchi, Carlo, Vivona, Luigi, Battistin, Michele, Colombo, Sebastiano M, Cattaneo, Emanuele, Protti, Ilaria, DI Feliciantonio, Marianna, Castelli, Gloria, Dondossola, Daniele, Biancolilli, Osvaldo, Carlin, Andrea, Gatti, Stefano, Pesenti, Antonio, Zanella, Alberto, Grasselli, Giacomo   +15 more
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Extracorporeal Carbon Dioxide Removal in ARDS

1991
The mortality rate due to acute respiratory failure (ARF) secondary to extensive inflammation of pulmonary parenchima (ARDS) varies, in different series, from 15% [1] to 90% [2] and this variability is not surprising since we are dealing with a syndrome whose etiology and subsequent outcome vary considerably.
L. Gattinoni, L. Brazzi, A. Pesenti.
openaire   +2 more sources

Extracorporeal Carbon Dioxide Removal

1989
We report the case of a 23-year-old man who was admitted to intensive care for ventilation following a presumed community-acquired pneumonia and whose respiratory failure required the use of a novel piece of equipment (the Novalung®) which allowed portable arterio-venous carbondioxide removal (AVCO2R).
L. Gattinoni, A. Pesenti, G. Damia
openaire   +2 more sources

Pumpless extracorporeal carbon dioxide removal for life-threatening asthma

Critical Care Medicine, 2007
To report the use of pumpless extracorporeal carbon dioxide removal in two cases of acute severe asthma.Case reports.Adult general intensive care unit, Leeds General Infirmary, Leeds, UK.A 74-yr-old male and 52-yr-old female with life-threatening asthma developed progressive hypercapnia and severe acidosis that proved nonresponsive to all other ...
Stuart C, Elliot, Kumar, Paramasivam, John, Oram, Andrew R, Bodenham, Simon J, Howell, Abhiram, Mallick   +5 more
openaire   +2 more sources

In-vitro performance of a low flow extracorporeal carbon dioxide removal circuit

Perfusion, 2019
Introduction: Extracorporeal gas exchange requires the passage of oxygen and carbon dioxide (CO 2 ) across an artificial membrane. Current European Union regulations do not require the transfer to be assessed in models using clinically relevant ...
Nicholas A Barrett, Nicholas Hart, Luigi Camporota   +2 more
openaire   +3 more sources

Arteriovenous Extracorporeal Carbon Dioxide Removal A Mathematical Model and Experimental Evaluation

ASAIO Journal, 1998
To explore the feasibility and operating limits of arteriovenous extracorporeal CO2 removal (AVCO2R) for support of acute respiratory failure, the authors developed a mathematical model to simulate (AVCO2R), evaluate the effects of several parameters used in its application, and predict the feasibility and necessary conditions for total CO2 removal ...
S A, Conrad, E G, Brown, L R, Grier, J, Baier, J, Blount, T, Heming, J B, Zwischenberger, A, Bidani   +7 more
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Extracorporeal carbon dioxide removal (ECCO2R) in patients with acute respiratory failure

Intensive Care Medicine, 2017
To review the available knowledge related to the use of ECCO2R as adjuvant strategy to mechanical ventilation (MV) in various clinical settings of acute respiratory failure (ARF).Expert opinion and review of the literature.ECCO2R may be a promising adjuvant therapeutic strategy for the management of patients with severe exacerbations of COPD and for ...
Morelli, A., Del Sorbo, L., Pesenti, A., Ranieri, V. M., Fan, E.   +4 more
openaire   +4 more sources

Low-frequency positive-pressure ventilation with extracorporeal carbon dioxide removal

Critical Care Medicine, 1990
Successful use of a new technique, low-frequency positive-pressure ventilation with extracorporeal CO2 removal (LFPPV-ECCR) is presented. The association of fulminant respiratory failure with CNS hemangioblastoma, described in the present patient, has been reported only once before, in 1928.
J H, Abrams, I J, Gilmour, J M, Kriett, P B, Bitterman, R J, Irmiter, R C, McComb, F B, Cerra   +6 more
openaire   +2 more sources