Results 131 to 140 of about 59,266 (247)

Optimization of the Nonclinical Biological Evaluation of Medical Devices Using Toxicologic Pathology Best Practices

Advanced Healthcare Materials, Volume 15, Issue 3, 19 January 2026.
Nonclinical evaluation of biological responses to implanted medical devices and combination products in animals is required to predict possible outcomes and risks in patients. This paper describes globally accepted pathology “best practices” that 1) effectively address ISO standards and current regulatory guidance for medical device development and 2 ...
Kathleen A. Funk, JoAnn C. L. Schuh, Brad Bolon, Valerie S. Thomas, Jeffrey I. Everitt, Abraham Nyska, Jaime Paulin   +6 more
wiley   +1 more source

Efectos de la circulación extracorpórea sobre el filtrado glomerular en la cirugía cardiovascular pediátrica Effects of extracorporeal circulation on glomerular filtration in pediatric cardiovascular surgery

Revista Colombiana de Cardiología, 2011
Objetivo: conocer como afecta la circulación extracorpórea la función renal tomando como marcador la alteración del filtrado glomerular. Material y método: se realizó un estudio prospectivo, analítico y observacional en 63 pacientes pediátricos sometidos
Abel Facenda, Antolín Romero, Junior M Lima, Cruz M Contreras, Heilyn del Valle Montero, Manuel G Lima Montero   +5 more
doaj  

An Aptamer‐Based EXACT Anticoagulant as a Sustainable, Animal‐Free Alternative to Unfractionated Heparin

Advanced Science, Volume 13, Issue 4, 19 January 2026.
By simply conjugating thrombin's active‐site inhibitor, dabigatran, with an exosite inhibitor, aptamer HD1, the resulting EXosite‐ACTive site (EXACT) inhibitors show two orders of magnitude higher potency and selectivity via synergistic binding, while maintaining the aptamer's antidote‐reversible trait, yielding a potential substitute for the animal ...
Haixiang Yu, George Pitoc, Manqi Zhang, Jeffrey Clancy, James Frederiksen, Amy Yan, Samuel Francis, Rebecca Sullenger, Rachel Rempel, Susannah Gammell, Jillian Caiazzi, Bruce A. Sullenger   +11 more
wiley   +1 more source

Hemólise em circulação extracorpórea: estudo comparativo entre bomba de rolete e bomba centrífuga Hemolysis in extracorporeal circulation: a comparative study between roller and centrifugal pumps

Brazilian Journal of Cardiovascular Surgery, 1989
O uso de bomba centrífuga como suporte circulatório para pacientes em choque cardiogênico, após a realização de cirurgia cardíaca e como suporte para pacientes com falência cardíaca que estão aguardando doação para transplante cardíaco, tem sido ...
Paulo M Pêgo-Fernandes, Flávio Miura, Sérgio S Higa, Luiz Felipe P Moreira, Luís Alberto Dallan, Dalton A. F Chamone, Sérgio de Almeida Oliveira, Noedir A. G Stolf, Adib D Jatene   +8 more
doaj  

A Study of the Changes of Oxygen Consumption According to Body Temperature During Extracorporeal Circulation [PDF]

, 1990
Chong Sung Kim, Heon Geun Lee, Yong Lak Kim   +2 more
openalex   +1 more source

Beyond lipids: Systemic effects of lipoprotein apheresis

Transfusion, EarlyView.
Menatalla Nadim, Yamac Akgun
wiley   +1 more source

Activation of USP30 Disrupts Endothelial Cell Function and Aggravates Acute Lung Injury Through Regulating the S‐Adenosylmethionine Cycle

Advanced Science, Volume 13, Issue 2, 9 January 2026.
USP30 deubiquitinates and stabilizes MAT2A, thereby regulating DNA methylation and miRNA expression, which ultimately leads to disruption of lung endothelial barrier and inflammation. Abstract Microvascular dysfunction is a key contributor to the development of acute inflammatory diseases, characterized by heightened vascular hyperpermeability and ...
Baoyinna Baoyinna, Jinshan He, Jiaxing Miao, Nargis Shaheen, Boyu Xia, Cankun Wang, Qin Ma, Matthew C Bernier, Bryan A Whitson, Nuo Sun, Jing Zhao, Yutong Zhao   +11 more
wiley   +1 more source

Physiological coagulation can be maintained in extracorporeal circulation by means of shed blood separation and coating [PDF]

, 2003
J.M. Albes, Ingeborg M Stöhr, Mirko Kaluza, A. Siegemund, Dirk S. Schmidt, Rüdiger Vollandt, Thorsten Wahlers   +6 more
openalex   +1 more source

Delayed Diagnosis of Sézary Syndrome: Lessons From a Psoriasiform Presentation

Clinical Case Reports, Volume 14, Issue 1, January 2026.
ABSTRACT Pruritic erythroderma is not always psoriasis. Resistant cases require a broad evaluation for cutaneous lymphoma. Early, timely diagnosis prevents disease progression, improves outcomes, and enhances quality of life, highlighting the need for re‐evaluation when conventional treatments fail.
Sudhan Neupane, Anu Neupane, Sajjad Ahmed Khan, Huma Kausar   +3 more
wiley   +1 more source

Impact of Kidney Replacement Therapy During Extracorporeal Membrane Oxygenation Support in Terms of Mortality: A Systematic Review and Meta‐Analysis

Health Science Reports, Volume 9, Issue 1, January 2026.
ABSTRACT Introduction Extracorporeal membrane oxygenation (ECMO) is a life‐saving intervention for refractory cardiopulmonary failure. Despite advancements reducing complications, ECMO remains associated with acute kidney injury (AKI), often requiring kidney replacement therapy (KRT). Studies report up to 45% of ECMO patients needing KRT, significantly
Ranjit Sah, Amita Paudel, Sangam Shah, Madhur Bhattarai, Sujata Bhandari, Bishwa Raj Adhikari, Sanjit Sah, Rachana Mehta, Anirban Bhattacharyya, Pablo Moreno Franco, Pramod Guru, Sanjay Chaudhary   +11 more
wiley   +1 more source