Results 151 to 160 of about 83,111 (274)

Serum lactate/albumin ratio at hospital arrival and neurological outcomes in patients who received targeted temperature management after out‐of‐hospital cardiac arrest: A nationwide, multicenter, observational study

open access: yesHong Kong Journal of Emergency Medicine, Volume 33, Issue 3, June 2026.
Abstract Background A lower serum lactate/albumin ratio has been linked to favorable outcomes in critically ill patients. Objective We investigated whether the serum lactate/albumin ratio could predict the likelihood of benefiting from targeted temperature management (TTM) after out‐of‐hospital cardiac arrest (OHCA). Methods Using a nationwide Japanese
Tetsuro Nishimura   +9 more
wiley   +1 more source

Pediatric Therapeutic Plasma Exchange: Characterization of Practice, Epidemiology, and Safety Profile at a Children's Hospital in the United States

open access: yesJournal of Clinical Apheresis, Volume 41, Issue 3, June 2026.
ABSTRACT There is a need to better understand the indications and safety profiles for therapeutic plasma exchange (TPE) in children. We aimed to assess pediatric TPE practice at a large academic center by retrospective chart review from 2011 to 2022. Patient demographics and clinical information including American Society for Apheresis (ASFA) category ...
Benjamin C. Lee   +4 more
wiley   +1 more source

A Case Series of Sudden Death in Children Aged 12 Months to 4 Years From LPIN1 Deficiency and PPA2 Deficiency in Queensland

open access: yes
Journal of Paediatrics and Child Health, EarlyView.
Sophie Manoy   +11 more
wiley   +1 more source

Mitochondrial Transplantation as a New Therapeutic Approach Against Cardiac and Renal Consequences in Male Rats With Myocardial Infarction

open access: yesActa Physiologica, Volume 242, Issue 6, June 2026.
ABSTRACT Aim Myocardial infarction (MI) is one of the leading causes of death worldwide. MI is associated with cardiac structural and functional alterations. Among these, cardiac fibrosis may be significantly influenced by mitochondrial dysfunction. We sought to evaluate whether the injection of functional mitochondria from healthy muscle could improve
María Cuesta‐Corral   +13 more
wiley   +1 more source

Evaluating Modified Early Warning Score Compliance to Minimize Unnecessary Intensive Care Unit Admissions: A Descriptive Cross‐Sectional Needs Assessment at a University Teaching Tertiary Care Centre to Inform Quality Improvement Implementation

open access: yesJournal of Evaluation in Clinical Practice, Volume 32, Issue 4, June 2026.
ABSTRACT Background Intensive Care Unit (ICU) resources are scarce in low‐ and middle‐income countries (LMICs), with a median of 0.7 beds per 100,000 population. The Modified Early Warning Score (MEWS) aids early identification of clinical deterioration and supports standardized escalation and ICU triage decisions to optimize critical‐care resource use.
Mazhar Khalil   +15 more
wiley   +1 more source

Pharmacokinetics of dolutegravir, tenofovir and lamivudine during venous–venous extracorporeal membrane oxygenation (VV‐ECMO): A case report

open access: yesBritish Journal of Clinical Pharmacology, Volume 92, Issue 5, Page 1487-1492, May 2026.
While providing potentially life‐saving cardiorespiratory support for critically ill patients, extracorporeal membrane oxygenation (ECMO) may detrimentally affect pharmacokinetic (PK) performance and concurrent drug efficacy and safety. We describe a patient with Pneumocystis jirovecii pneumonia (PJP) in the context of acquired immunodeficiency ...
Tom C. Zwart   +7 more
wiley   +1 more source

How Epigenetics Bridges Genes and Environment: A Multiomics Evidence Chain in Congenital Diaphragmatic Hernia

open access: yesBirth Defects Research, Volume 118, Issue 5, May 2026.
ABSTRACT Background/Objectives Congenital diaphragmatic hernia (CDH) is a severe developmental anomaly with high etiological heterogeneity. Although numerous susceptibility genes have been identified, genetic factors alone fail to explain the full disease risk. Epidemiological data highlight the contribution of environmental exposures.
Yunshan Gao   +8 more
wiley   +1 more source

Giant Mediastinal Teratoma in a Child: A Case Report With a Brief Review of the Literature

open access: yesClinical Case Reports, Volume 14, Issue 5, May 2026.
Contrast‐enhanced axial chest CT showing a large, well‐circumscribed mediastinal mass measuring approximately 15.9 × 14.1 cm (maximum axial dimensions). The lesion is predominantly of fluid attenuation, occupies nearly the entire left hemithorax, and produces marked rightward deviation of the mediastinum, compression of the contralateral lung ...
Urías Hernandez Lopez   +5 more
wiley   +1 more source

Two Cases of Kounis Syndrome Caused by Contrast Medium: Early Extracorporeal Membrane Oxygenation

open access: yesClinical Case Reports, Volume 14, Issue 5, May 2026.
ABSTRACT In cardiology, Kounis syndrome (KS), also known as allergic angina or myocardial infarction, is often overlooked in emergencies. Its pathophysiology differs from that of allergic reactions such as anaphylaxis, making differentiation essential.
Kiichi Yano   +5 more
wiley   +1 more source

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