Results 101 to 110 of about 3,931 (193)

Compassionate use of ruxolitinib in acute and chronic graft versus host disease refractory both to corticosteroids and extracorporeal photopheresis

Experimental Hematology & Oncology, 2017
Background Ruxolitinib is a potent inhibitor of JAK1/2 with proven efficacy in myelofibrosis. In recent years, research in graft versus host disease (GVHD) has revealed the role of activation of JAK pathways in alloreactive lymphocytes. Some reports have
Mauricio Sarmiento Maldonado, Pablo Ramírez Villanueva, Pablo Bertín Cortes-Monroy, Veronica Jara Arias, Katherine Soto Donoso, Pablo Uribe Gonzalez, Mauricio Ocqueteau Tachini, Jose Antonio Perez-Simón   +7 more
doaj   +1 more source

Modulation Of Immunity By The Immunologic Zipper: The Role Of Glucocorticoid-Induced Leucine Zipper In Extracoporeal Photochemotherapy [PDF]

, 2014
Extracorporeal photochemotherapy (ECP) is a cellular therapy that is FDA approved for the treatment of a variety of T cell mediated diseases, including cutaneous T cell lymphoma, graft-versus-host disease, and solid organ transplantation rejection.
Feng, Hao
core   +1 more source

Protocol to study phagocytosis of apoptotic murine splenocytes by syngeneic antigen-presenting cells in vitro

STAR Protocols
Summary: Extracorporeal photopheresis (ECP) effectively reduces immune checkpoint inhibitor (ICI)-induced colitis and is based on the phagocytic uptake of apoptotic ECP-treated splenocytes.
Lukas M. Braun, Robert Zeiser
doaj   +1 more source

8-Mop/uva Inhibits Maturation Of Extracorporeal Photochemotherapy (ecp) Generated Dendritic Cells [PDF]

, 2011
Extracorporeal photochemotherapy (ECP), a cellular therapy involving a light activated drug, is FDA approved for the treatment of Cutaneous T-cell lymphoma (CTCL) and used for reversal of Graft-versus-Host Disease (GHVD) and solid organ transplant ...
Baird, Abigail Hart
core   +1 more source

Early extracorporeal photopheresis treatment is associated with better survival in patients with chronic or recurrent acute lung allograft dysfunction [PDF]

Background Due to development of chronic lung allograft dysfunction (CLAD), prognosis for patients undergoing lung transplantation (LTx) is still worse compared to other solid organ transplant recipients.
Gautschi, Fiorenza, Hage, René, Knörr, Fabian, Nägeli, Mirjam, Ortmanns, Gernot, Schuurmans, Macé Matthew, Steinack, Carolin, Vogelmann, Tobias   +7 more
core   +1 more source

Extracorporeal photopheresis vs. systemic immunosuppression for immune-related adverse events: Interim analysis of a prospective two-arm study [PDF]

Background Checkpoint inhibitor-induced steroid-refractory (sr) and steroid-dependent (sd) immune-related adverse events (irAE) account for about 11 % of irAE.
Bonczkowitz, P., David-Rus, R., de Toni, E. N., Ertl, C., French, L. E., Garza Vazquez, X., Hammann, L., Heinzerling, L. M., Kabakci, C., Piseddu, I., Ruf, T., Schmitt, C., Srour, J., Tomsitz, D., Wang, Y.   +14 more
core   +1 more source

Clinical and immunological aspects of extracorporeal photochemotherapy for psoriasis and psoriatic arthritis

Терапевтический архив, 2012
Aim. To evaluate the clinical efficiency of extracorporeal photochemotherapy (EPCT) in the treatment of psoriasis (Ps) and Ps associated with psoriatic arthritis (PsA). Subjects and methods.
V A Molochkov, A V Kil'diushevskiĭ, A V Molochkov, O V Karzanov, E S Iakubovskaia, V A Fedulkina   +5 more
doaj  

Potential Biomarkers of Therapeutic Response to ECP in Solid Organ Transplantation

Transplantation Direct
One of the major hurdles in solid organ transplantation is graft rejection, which must be prevented with lifelong general immunosuppression. However, modern maintenance immunosuppression is accompanied by serious side effects, such as an increased risk ...
Hendrik Veltman, Msc, Eva Martinez-Caceres, PhD, Maria Iglesias-Escudero, PhD   +2 more
doaj   +1 more source

Beyond 8-methoxypsoralen as the photosensitizer for extracorporeal photopheresis

Frontiers in Oncology, 2022
Yandy Marx Castillo-Aleman
doaj   +1 more source

Protocol to study in vivo organ-specific migration of apoptotic splenocytes in mice with tumor and immune checkpoint inhibitor-induced colitis

STAR Protocols
Summary: Extracorporeal photopheresis (ECP) reduces immune checkpoint inhibitor (ICI)-induced colitis without affecting anti-tumor immunity. Here, we provide a protocol to trace ECP-treated cells in vivo after transfer into tumor-bearing mice with ICI ...
Lukas M. Braun, Robert Zeiser
doaj   +1 more source