Results 21 to 30 of about 172 (100)

Effectiveness and safety of methotrexate in the treatment of mycosis fungoides: Real‐world data from a multicentre study

Journal of the European Academy of Dermatology and Venereology, EarlyView.
Methotrexate (MTX) has been a longstanding therapeutic option for mycosis fungoides (MF); however, data on its real‐world effectiveness remain limited. This study aimed to assess real‐world outcomes of oral MTX in the treatment of MF. Data from five referral centres for cutaneous lymphoma in Greece were retrospectively reviewed with the baseline‐ and ...
Vasiliki Nikolaou, Evdoxia Panou, Antonios Tsimpidakis, Ioannis‐Alexios Koumprentziotis, Aikaterini Patsatsi, Marina Siakantaris, Sabine‐Elke Kruger‐Krasagakis, Leonidas Marinos, Elisavet Georgiou, Kyriaki Lampadaki, Aliki Velissari, Athina‐Ioanna Daponte, Aikaterini Doxastaki, Stella Kaliampou, Aristeidis Vaiopoulos, Iliana Konstandinou, Marios Koumourtzis, Eleftheria Lakiotaki, Vassiliki Pappa, Athanasios Tsamaldoupis, Alexander Stratigos, Evangelia Papadavid   +21 more
wiley   +1 more source

Application experience of extracorporeal photopheresis for treatment of acute “graft-versus-host” disease after allogeneic hematopoietic stem cell transplantation

Онкогематология, 2014
Extracorporeal photopheresis (ECP) has been used as a component of combined immunosuppressive therapy in 53 patients with steroid-refractoryacute “graft-versus-host” disease.
A. V. Kozlov, T. A. Bykova, I. I. Kulagina, S. N. Bondarenko, E. V. Semenova, l. S. Zubarovskaya, B. V. Afanasyev   +6 more
doaj   +3 more sources

OF PHOTOPHERESIS IN KIDNEY TRANSPLANTATION

Вестник трансплантологии и искусственных органов, 2018
Aim – to perform a comparative study of the long-term results of the combined use of extracorporeal photochemotherapy (photopheresis) and drug immunosuppression and standard immunosuppressive therapy in patients after kidney transplantation.Materials and
A. P. Faenko, A. B. Zulkarnayev, Ju. Ju. Chuksina, V. A. Fedulkina, R. O. Kantaria, A. V. Kildyushevskiy, A. V. Vatazin   +6 more
doaj   +1 more source

A survey of extracorporeal photopheresis treatment in pediatric patients in the United Kingdom

eJHaem, 2020
Extracorporeal photopheresis (ECP) is a second‐line therapy in acute and chronic GVHD and solid organ transplant rejection. We report ECP use in 98 pediatric patients in seven UK centers from 2010 to 2017, the majority treated for aGVHD (73.5%).
Aisling M. Flinn, Sheba Macheka, Mary Slatter, Anna‐Maria Ewins, Brenda Gibson, Sarah Lawson, Anna Tailby, Giovanna Lucchini, Helen New, Beki James, Arun Alfred, Julia Scarisbrick, Andrew R Gennery   +12 more
doaj   +1 more source

Should we use extracorporeal photopheresis more often? Evidence from graft-versus-host disease patients monitored with Treg as a biomarker

Future Science OA, 2020
Background: Chronic graft-versus-host disease (cGvHD) is a major complication after allogeneic hematopoietic cell transplantation. Extracorporeal photopheresis (ECP) is an immunotherapy treatment for cGvHD, although suitable response biomarkers are ...
Sérgio Machado Lopes, Susana Roncon, Ana Catarina Pinho, Filipa Bordalo, Luís Antunes, Fernando Campilho, António Campos, Altamiro Costa-Pereira   +7 more
doaj   +1 more source

Models for plasma kinetics during simultaneous therapeutic plasma exchange and extracorporeal membrane oxygenation [PDF]

arXiv, 2020
This paper focuses on the derivation and simulation of mathematical models describing new plasma fraction in blood for patients undergoing simultaneous extracorporeal membrane oxygenation and therapeutic plasma exchange. Models for plasma exchange with either veno-arterial or veno-venous extracorporeal membrane oxygenation are considered.
arxiv  

Management challenge of a rare concomitant platelet glycoprotein IV/CD36 and IIb/IIIa deficiencies: Case illustration

Transfusion, Volume 65, Issue 4, Page 767-772, April 2025.
Abstract Introduction/Background Platelet membrane glycoproteins (GPs) serve several functions, the most significant of which is their role in primary hemostasis. Among these, GP IIb/IIIa is the primary fibrinogen receptor and is essential for platelet aggregation.
Tro Sekayan, Elizabeth S. Allen, Patricia Kopko, Laura D. Stephens, Mitchell Zhao, Brian R. Curtis, Mia J. Sullivan, Valerie Trapp‐Stamborski, Annette von Drygalski   +8 more
wiley   +1 more source

Extracorporeal photopheresis as second-line treatment for acute graft-versus-host disease: impact on six-month freedom from treatment failure

Haematologica, 2014
Second-line therapy for corticosteroid-refractory or -dependent acute graft-versus-host disease remains ill-defined, due to limited efficacy of drugs and evolving clinical trial endpoints.
Emma Das-Gupta, Hildegard Greinix, Ryan Jacobs, Li Zhou, Bipin N. Savani, Brian G. Engelhardt, Adetola Kassim, Nina Worel, Robert Knobler, Nigel Russell, Madan Jagasia   +10 more
doaj   +1 more source

Novel drugs approved by the EMA, the FDA and the MHRA in 2024: A year in review

British Journal of Pharmacology, Volume 182, Issue 7, Page 1416-1445, April 2025.
Abstract In the past year, the European Medicines Agency (EMA), the Food and Drug Administration (FDA) and the Medicines and Healthcare Products Regulatory Agency (MHRA) authorised 53 novel drugs. While the 2024 harvest is not as rich as in 2023, when 70 new chemical entities were approved, the number of ‘orphan’ drug authorisations in 2024 (21) is ...
Stavros Topouzis, Andreas Papapetropoulos, Steve P. H. Alexander, Miriam Cortese‐Krott, Dave A. Kendall, Kirill Martemyanov, Claudio Mauro, Nithyanandan Nagercoil, Reynold A. Panettieri Jr, Hemal H. Patel, Rainer Schulz, Barbara Stefanska, Gary J. Stephens, Mauro M. Teixeira, Nathalie Vergnolle, Xin Wang, Péter Ferdinandy   +16 more
wiley   +1 more source

Extracorporeal photopheresis for the treatment of chronic graft versus host disease

Hematology, 2022
Objectives Chronic graft versus host disease (chronic GVHD) still remains the leading cause of late morbidity and mortality for allogeneic hematopoietic stem cell transplant (allo-HSCT) recipients.
Emin Kansu, David Ward, Amber P. Sanchez, Robyn Cunard, Mutlu Hayran, Beril Huseyin, Majella Vaughan, Grace Ku, Peter Curtin, Carolyn Mulroney, Caitlin Costello, Januario E. Castro, Matthew Wieduwilt, Sue Corringham, Anita Ihasz-Davis, Connie Nelson, Edward D. Ball   +16 more
doaj   +1 more source