Results 111 to 120 of about 4,331,631 (311)

AAA+ protein unfoldases—the Moirai of the proteome

open access: yesFEBS Letters, EarlyView.
AAA+ unfoldases are essential molecular motors that power protein degradation and disaggregation. This review integrates recent cryo‐electron microscopy (cryo‐EM) structures and single‐molecule biophysical data to reconcile competing models of substrate translocation.
Stavros Azinas, Marta Carroni
wiley   +1 more source

Optimization of genistein and daidzein extraction from a tempeh-fermented product of soybean [PDF]

open access: yesJournal of Pharmacy & Pharmacognosy Research, 2018
Context: Genistein and daidzein, major isoflavone aglycone compounds contained in tempeh, became an interesting subject since their activities as cancer prevention, cardiovascular, and wound healing agents.
Sri H. Yuliani   +3 more
doaj  

PENGARUH PEMBERIAN EKSTRAK KUNYIT (Curcuma longa) TERHADAP JUMLAH EOSINOFIL DI JARINGAN PARU PADA PENYAKIT ALERGI : Studi Eksperimental pada Mencit BALB/c yang Diinduksi Ovalbumin [PDF]

open access: yes, 2016
Background: Turmeric (Curcuma longa) is a spice that is often used as traditional medicine. The active ingredient of turmeric, curcumin, acts as an anti-inflammatory on the allergic reaction.
Ningrum, Tri Setya   +2 more
core   +1 more source

Protective Effect of Lemon (Citrus Limon L.) Ethanol Extract Cream as an Antioxidant Against Exposure to Ultraviolet B Rays in the Skin of Male Wistar (Rattus Norvegicus) Rats [PDF]

open access: yes, 2020
Background: Indonesia is an archipelagic country and one of the tropical countries that get sun exposure all the time. Sun exposure can have beneficial and detrimental effects in life. Exposure to radiation can cause acute effects in the form of erythema
Dewanti, D. A. (Dewa)   +4 more
core  

Residual tail twisting in ascidian larvae is stabilized by asymmetric myofibrils that resist bilateral symmetry restoration

open access: yesFEBS Letters, EarlyView.
Ascidian Ciona larvae initially show strong clockwise tail twisting, which is largely corrected during development. However, a small residual twist remains. This study shows that organized helical myofibrils in tail muscles mechanically stabilize this residual asymmetry, preventing complete restoration of bilateral symmetry and revealing how embryos ...
Yuki S. Kogure   +3 more
wiley   +1 more source

The human gut microbiome across the life course

open access: yesFEBS Letters, EarlyView.
Despite significant individual variation and continuous change throughout life, the human gut microbiome follows some life stage‐specific trends. This article provides a brief overview of how gut microbiome composition shifts across different phases of life. Created in BioRender. Özkurt, E. (2026) https://BioRender.com/8q4nrnc.
Alise J. Ponsero   +4 more
wiley   +1 more source

In Vitro Antioxidant Activity of Methanolic Extract of Piper retrofractum Vahl. [PDF]

open access: yes, 2015
Cabai jamu (Piper retrofractum Vahl.), which is originally from Indonesia and is extensively cultivated and traditionally used in Sumenep, Madura possess high potential medicinal properties.
Abdulgani, Nurlita   +4 more
core  

Transcriptional network analysis of PTEN‐protein‐deficient prostate tumors reveals robust stromal reprogramming and signs of senescent paracrine communication

open access: yesMolecular Oncology, EarlyView.
Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice   +16 more
wiley   +1 more source

Infrared laser sampling of low volumes combined with shotgun lipidomics reveals lipid markers in palatine tonsil carcinoma

open access: yesMolecular Oncology, EarlyView.
Nanosecond infrared laser (NIRL) low‐volume sampling combined with shotgun lipidomics uncovers distinct lipidome alterations in oropharyngeal squamous cell carcinoma (OPSCC) of the palatine tonsil. Several lipid species consistently differentiate tumor from healthy tissue, highlighting their potential as diagnostic markers.
Leonard Kerkhoff   +11 more
wiley   +1 more source

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