Results 151 to 160 of about 2,057,765 (299)
Pond's Extract Vegetable Pain Destroyer
, 2017 Trade card advertising Pond's Extract, a remedy prepared by the Pond's Extract Co., New York, N.Y.
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Loss of IGF‐1R impairs DNA‐PKcs recruitment to chromatin leading to defective end‐joining
Molecular Oncology, EarlyView.IGF‐1R promotes radioresistance by facilitating DNA‐PKcs recruitment to chromatin, enabling non‐homologous end‐joining (NHEJ) repair of double‐strand breaks. Inhibition or loss of IGF‐1R disrupts this recruitment to damage sites, driving compensatory reliance on microhomology‐mediated end‐joining (MMEJ) repair.
Matthew O. Ellis +3 more
wiley +1 more source
Pond's Extract for inflammation and hemorrhages
, 2017 Trade card advertising Pond's extract, a remedy prepared by the Pond's Extract Co., New York, N ...
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Molecular Oncology, EarlyView.We identify USP29 as the only DUB mirroring CA9 expression, a marker of hypoxia and HIF pathway activation associated with PCA aggressiveness. USP29 stabilizes HIF‐1α and HIF‐2α via a noncanonical mechanism that is independent of PHD/pVHL activity yet relies on proteasomal regulation, establishing USP29 as a previously unrecognized regulator of hypoxic
Amelie S Schober +16 more
wiley +1 more source
Pond's Extract Vegetable Pain Destroyer
, 2016 Trade card advertising Pond's Extract, a remedy prepared by the Pond's Extract Co., New York, N.Y.
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Finding novel vulnerabilities of hypomorphic BRCA1 alleles
Molecular Oncology, EarlyView.Synthetic lethality screens performed to identify novel vulnerabilities often model complete gene loss, thereby overlooking patient‐derived hypomorphic mutations. In this study, we have performed genome‐wide CRISPR screens on BRCA1 hypomorphic mutations, showing BRCA1I26A behaves like wild‐type, while BRCA1R1699Q mimics deficiency. Furthermore, we have
Anne Schreuder +10 more
wiley +1 more source
Efficacy of plant extracts in heart failure patients: a systematic review and network meta-analysis. [PDF]
BMC Cardiovasc DisordTang T, Li G, Huang X, Liang H.
europepmc +1 more source
SETLr: the semantic extract, transform, and load-r
, 2018 Semantic Extract, Transform, and Load-er (SETLr) is a flexible, scalable tool for providing semantic interpretations to tabular, XML, and JSON-based data from local or web files.
McCusker, Jamie +4 more
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MITF maintains genome stability in nonmelanocyte lineages
Molecular Oncology, EarlyView.MITF is essential for melanocyte survival and acts as an oncogene in 10%–20% of melanomas. We show that MITF depletion causes genome instability in nonmelanocytic cells, leading to LATS2‐mediated P53 activation, cell cycle arrest, and apoptosis. This study highlights the role of MITF as a genome maintenance factor beyond the melanocyte lineage. Created
Drifa H. Gudmundsdottir +13 more
wiley +1 more source
They won't kick against Pond's Extract
, 2016 Trade card advertising Pond's Extract, a remedy prepared by the Pond's Extract Co., New York, N.Y. This card has an 1894 copyright date.
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