Results 71 to 80 of about 1,984,454 (288)

Extracellular matrix remodeling and immune reprogramming drive residual tumor progression of liver cancer after incomplete microwave ablation

Molecular Oncology, EarlyView.
Incomplete microwave ablation (iMWA) of liver cancer triggers a biphasic progression in residual tumors. At Day 3, the microenvironment is characterized by acute inflammatory responses and extracellular matrix (ECM) remodeling. By Day 14, a profound shift occurs toward oncogenic signal transduction and immunosuppression, marked by macrophage ...
Yu Liu, Yubei He, Nikolaus Berndt, Michael Mülleder, Kathrin Textoris‐Taube, Jing Guo, Matthias Stechele, Justus Ramtke, Shraga Nahum Goldberg, Lynn Jeanette Savic   +9 more
wiley   +1 more source

SPHINX31 acts as a SRPK1 inhibitor targeting the ATR/DNA‐PKcs/CHK1 replicative checkpoint to inhibit cell growth in non‐small cell lung cancer

Molecular Oncology, EarlyView.
The kinase SRPK1 directly interacts with the protein TOPBP1 and regulates the pre‐mRNA splicing of WIZ thereby contributing to the activation of the ATR/CHK1 replicative checkpoint in response to replicative stress. This allows cancer cells' genomic stability and survival.
Amani Shreim, Aurelie Genoux, Nadiia Zubchuk, Haoyang Zheng, Perla Salameh, Theo Ziegelmeyer, Fabien Dalonneau, Margot Rouchette, Christiane Oddou, Simona Miron, Helene Polveche, Adiilah Mamode Cassim, Carmen Garrido, Eleni Nikolakaki, Didier Auboeuf, Tao Jia, Sophie Zinn‐Justin, Beatrice Eymin   +17 more
wiley   +1 more source

Principais técnicas de preparo de amostra para a determinação de resíduos de agrotóxicos em água por cromatografia líquida com detecção por arranjo de diodos e por espectrometria de massas

Química Nova, 2011
The determination of pesticide residues in water samples by Liquid Chromatography require sample preparation for extraction and enrichment of the analytes with the minimization of interferences to achieve adequate detection limits.
Sergiane Souza Caldas, Fábio Ferreira Gonçalves, Ednei Gilberto Primel, Osmar Damian Prestes, Manoel Leonardo Martins, Renato Zanella   +5 more
doaj   +1 more source

Optimization of seminal extracellular vesicle isolation protocols for cancer biomarker analysis using proteomic profiling

Molecular Oncology, EarlyView.
This paper shows that size‐exclusion chromatography and sequential centrifugation applied to seminal plasma enrich for different populations of extracellular vesicles. This may significantly affect the detection and analysis of extracellular vesicle‐associated cancer biomarkers.
Elen Telumyan, Beatriz Martín‐Gracia, Eva Bassols‐Citores, Krizia Sagini, Maria K. Andersen, Tuula A. Nyman, May‐Britt Tessem, Morten B. Rye, Alicia Llorente   +8 more
wiley   +1 more source

Optimization Ultrasound-Assisted Deep Eutectic Solvent Extraction of Anthocyanins from Raspberry Using Response Surface Methodology Coupled with Genetic Algorithm

Foods, 2020
Raspberries have been reported to contain abundant anthocyanins and other active compounds. To extract anthocyanins from raspberries more efficiently, a novel procedure of ultrasound-assisted deep eutectic solvent extraction (UADESE) was proposed in this
Hongkun Xue, Jiaqi Tan, Qian Li, Jintian Tang, Xu Cai   +4 more
doaj   +1 more source

Determination of trace levels of phenol and cresols in rain by continuous liquid-liquid extraction and high-performance liquid chromatography

, 1987
Trace levels of phenol and methylphenols (cresols) in aqueous samples were determined by continuous liquid-liquid extraction and normal-phase high-performance liquid chromatography with UV-fluorescence detection.
Leuenberger, Christian (author), Giger, Walter (author), Tremp, Josef (author), Czuczwa, Jean (author), Ahel, Marjian (author)   +4 more
core   +1 more source

Tumour‐proximal deep serum proteomics identifies biomarkers associated with ovarian cancer

Molecular Oncology, EarlyView.
New biomarkers are needed for early ovarian cancer detection. Ovarian (tumour‐proximal) and peripheral vein serum from healthy women and patients with benign or malignant tumours underwent nanoparticle‐enriched deep proteomics. Ovarian serum yielded more protein identifications and revealed tumour‐reflective signatures.
Darren Lau, Daniel Pincher, Clifford Young, Nicholas Chappell, Noor A. Lokman, Parul Mittal, Leigh Donnellan, Martin K. Oehler, Doug A. Brooks, Peter Hoffmann   +9 more
wiley   +1 more source

Extraction Chromatography: Progress and Opportunities [PDF]

, 1999
Extraction chromatography provides a simple and effective method for the analytical and preparative-scale separation of a variety of metal ions. Recent advances in extractant design, particularly the development of extractants capable of metal ion recognition or of strong complex formation in highly acidic media, have significantly improved the utility
Dietz, M. L., Horwitz, E. P., Bond, A. H.   +2 more
openaire   +1 more source

Extraction, purification, biological effects and applications of acrosin: a review

Frontiers in Cellular and Infection Microbiology
Acrosin is a proteolytic enzyme in the sperm acrosome that can stimulate sperm to penetrate the zona pellucida, causing the fertilization of the oocyte.
Run Quan, Xiaolong Wu, Junjie Zhang, Rongxu Liu, Jianchun Han, Jianchun Han, Danyi Liu   +6 more
doaj   +1 more source

Extraction Chromatography: Progress and Opportunities [PDF]

, 1997
Extraction chromatography provides a simple and effective method for the analytical and preparative-scale separation of a variety of metal ions. Recent advances in extractant design, particularly the development of extractants capable of metal ion ...
Bond, A. H., Horwitz, E. P., Dietz, M. L.   +2 more
core