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The human gut microbiome across the life course
Despite significant individual variation and continuous change throughout life, the human gut microbiome follows some life stage‐specific trends. This article provides a brief overview of how gut microbiome composition shifts across different phases of life. Created in BioRender. Özkurt, E. (2026) https://BioRender.com/8q4nrnc.
Alise J. Ponsero +4 more
wiley +1 more source
Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang +2 more
wiley +1 more source
Aiming at the problems existing in current bench line extraction methods based on open-pit mine point cloud data, such as single judgment basis, poor spatial adaptability, high false detection rate, and low levels of automation and extraction efficiency,
Jingchang ZHAO +4 more
doaj +1 more source
Encapsulins are protein nanocompartments that play an important role in iron storage. In the Myxococcus xanthus encapsulin system, two cargo proteins called EncB and EncC contribute to iron mineralization. Here, we show that EncB and EncC generate iron‐containing minerals with distinct chemical compositions, suggesting that the composition of stored ...
Harry B. McDowell +2 more
wiley +1 more source
The interpretation of open-pit coal mining activity is critical for resource management and ecological protection. It comprises two key tasks: extent extraction and fine-grained change detection.
Jianghe Xing +8 more
doaj +1 more source
Heterodimeric amino acid transporters consist of SLC7 and SLC3 family proteins arranged in a conserved structural organization. They regulate nutrient transport across cell membranes, supporting essential cellular functions. These transporters also contribute to xenobiotic/drug uptake and distribution.
Mariafrancesca Scalise +5 more
wiley +1 more source
Recent interest has been growing concerning points of maximum depth within folds, the sulcal pits, that can be used as reliable cortical landmarks. These remarkable points on the cortical surface are defined algorithmically as the outcome of an automatic extraction procedure. The influence of several crucial parameters of the reference technique (Im et
Auzias, G. +3 more
openaire +2 more sources
The Effect of Gaussian Blurring on the Extraction of Peaks and Pits from Digital Elevation Models [PDF]
Gaussian blurring is an isotropic smoothing operator that is used to remove noise and detail from images. In this paper, the effect of Gaussian blurring on the extraction of peaks and pits from digital elevation models (DEMs) is studied. First, a mathematical morphological-based algorithm to extract peaks and pits from DEMs is developed.
A. Pathmanabhan, S. Dinesh
openaire +4 more sources
Kinetic dependences for the extraction of apricot pits kernels with ethanol-water solvent
Abstract During the extraction of a capillary-porous body, such as the nuclei of fruit seeds, the movement of the distributed substance in the solid phase is carried out by means of molecular diffusion. The amount of material flow in a solid per unit surface is determined by Fick’s law using the diffusion coefficient.
Karim Gafurov +5 more
openaire +1 more source
The lignite mining extraction within the mining perimeter in Rovinari is carried out through mining works in the open, by using large equipments for the excavation, transport and storage of the mining material.
George Popescu +3 more
doaj +1 more source

