Results 51 to 60 of about 3,723 (184)

The X Factor in Immunity: Sex Differences Shaped by the X Chromosome

Immunological Reviews, Volume 338, Issue 1, March 2026.
ABSTRACT There are sex differences with immune responses where females exhibit stronger immune responses compared to males. Both sex hormones and sex chromosome differences between males and females contribute to the observed sex differences with innate and adaptive immune cell composition and function.
Katherine B. Radovanovic, Megan Wynalda, Montserrat C. Anguera   +2 more
wiley   +1 more source

Spatiotemporal segmentation of contraction waves in the extra-embryonic membranes of the red flour beetle

BMC Bioinformatics
Background In this paper, we introduce an image analysis approach for spatiotemporal segmentation, quantification, and visualization of movement or contraction patterns in 2D+t and 3D+t microscopy recordings of biological tissues. The development of this
Marc Pereyra, Mariia Golden, Zoë Lange, Artemiy Golden, Frederic Strobl, Ernst H. K. Stelzer, Franziska Matthäus   +6 more
doaj   +1 more source

Conceptus signals for establishment and maintenance of pregnancy

Reproductive Biology and Endocrinology, 2004
Establishment and maintenance of pregnancy results from signaling by the conceptus (embryo/fetus and associated extraembryonic membranes) and requires progesterone produced by the corpus luteum (CL).
Bazer Fuller W, Spencer Thomas E
doaj   +1 more source

Engineering a Perfusion Bioreactor System for hiPSC‐Derived Progenitor Co‐Culture Capturing Microglial Features in CNS Development

Biotechnology and Bioengineering, Volume 123, Issue 2, Page 363-378, February 2026.
The authors report the development of a controlled and scalable 3D co‐culture system combining hiPSC‐derived erythromyeloid progenitors and neurospheres within the Ambr® 250 Modular platform operated with a newly designed perfusion system. This model faithfully recapitulates early microglia–neural interactions, enabling progenitor integration ...
Catarina M. Gomes, Inês de Sá, Margarida Delgado, Paula M. Alves, Catarina Brito   +4 more
wiley   +1 more source

In Vivo Chemical Reprogramming Is Associated With a Toxic Accumulation of Lipid Droplets Hindering Rejuvenation

Aging Cell, Volume 25, Issue 2, February 2026.
Partial chemical reprogramming significantly increases mitochondrial interaction networks, affects mitochondrial morphology, speeds up mitochondrial movement dynamics, increases mitochondrial transmembrane potential, and induces TCA cycle stress. These changes in mitochondrial function contribute to lipid droplet accumulation, acute kidney injury, and ...
Wayne Mitchell, Cecília G. de Magalhães, Alexander Tyshkovskiy, Yushi Uchida, Ludger J. E. Goeminne, Takaharu Ichimura, Emery L. Ng, Alibek Moldakozhayev, Joseph V. Bonventre, Vadim N. Gladyshev   +9 more
wiley   +1 more source

Advances in non‐germ cell tumours of the testis: focus on new molecular developments in sex cord‐stromal tumours

Histopathology, Volume 88, Issue 1, Page 230-251, January 2026.
In this review, we summarise the major recent advances in Testicular Sex Cord‐Stromal Tumours, focusing on molecular alterations and biomarkers relevant for diagnosis, classification and prognosis. Testicular sex cord‐stromal tumours (TSCSTs) represent ~4%–8% of all testicular neoplasms.
João Lobo, Andres M Acosta
wiley   +1 more source

Germ cell and other tumors in individuals with differences in sex development

CA: A Cancer Journal for Clinicians, Volume 75, Issue 6, Page 587-601, November/December 2025.
Abstract Approximately one in 3500 to one in 5100 live‐born infants have atypical external genital development, known as differences in sex development (DSD). In 2005, an expert consensus conference thoroughly reviewed aspects of health care for individuals with DSD.
Selma Feldman Witchel, Miguel Reyes‐Múgica   +1 more
wiley   +1 more source

Elevating Testosterone and Androstenedione Produces Temporary Sex‐Dependent Variation in Japanese Quail (Coturnix japonica) Embryonic Development

Journal of Experimental Zoology Part A: Ecological and Integrative Physiology, Volume 343, Issue 9, Page 1103-1116, November 2025.
ABSTRACT Vertebrate growth rates may respond to maternally supplied steroids, yet injections of individual hormones into avian eggs of different species have produced inconsistent results. This might be because diverse steroids' concentrations are naturally correlated in yolks, injections are not elevating hormones at critical times in development, or ...
S. K. Winnicki, M. E. Hauber, R. T. Paitz, W. M. Schelsky, T. J. Benson   +4 more
wiley   +1 more source

Developmental potential of mouse embryos without extraembryonic membranes in modified organ culture.

Collegium antropologicum, 2004
The long-term stationary culture of postimplanatation embryos without extraembryonic membranes is a method to assess their developmental potential in vitro. The method was almost exclusively used on rat embryos, while mouse embryos were considered unsuitable due to their poor differentiation.
Stević, Nataša, Belovari, Tatjana, Kostović-Knežević, Ljiljana, Gajović, Srećko   +3 more
openaire   +4 more sources

Human Endogenous Retroviruses and Diseases

MedComm, Volume 6, Issue 11, November 2025.
Human endogenous retroviruses (HERVs), remnants of ancient retroviral integrations into the human genome, are modulated by viral infections, genetic inheritance, and triggers including environmental factors, epigenetic dysregulation, oncogene activation, and aging.
Can Chen, Yanru Cui, Shixiang Wang, Yuze Yang, Zunpeng Liu, Suhan Jin, Fangqian Shen, Udo Gaipl, Hu Ma, Jian‐Guo Zhou   +9 more
wiley   +1 more source