Results 61 to 70 of about 8,571 (229)

Gastrula‐Premarked Posterior Enhancer Primes Posterior Tissue Development Through Cross‐Talk with TGF‐β Signaling Pathway

Advanced Science, Volume 12, Issue 36, September 25, 2025.
A gastrula‐premarked enhancer within the first intron of Cdx2 governs posterior embryonic development via both regulating Cdx2 expression in cis and coordinating TGF‐β signaling in trans to ensure proper posterior body development. Functional rescue in gastruloids reveals a Cdx2‐independent pathway, highlighting p‐Enh‐eRNA as key epigenetic ...
Yingying Chen, Fengxiang Tan, Qing Fang, Lin Zhang, Jiaoyang Liao, Penglei Shen, Yun Qian, Mingzhu Wen, Rui Song, Yonggao Fu, He Jax Xu, Ran Wang, Cheng Li, Zhen Shao, Jinsong Li, Naihe Jing, Xianfa Yang   +16 more
wiley   +1 more source

X-chromosome inactivation mosaicism in the three germ layers and the germ line of the mouse embryo [PDF]

, 1982
Electrophoretic variant forms of the X-linked enzyme phosphoglycerate kinase (PGK-1, E.C.2, 7, 2, 3) have been used to examine X-chromosome mosaicism in tissues from 121/2-day post coitum heterozygous female mouse embryos.
Fosten, M., McMahon, A., Monk, M.
core  

Large‐Scale Bioprinting of Human Epiblast‐Like Models Featuring Disc‐Shaped Morphogenesis and Gastrulation Events

Advanced Science, Volume 12, Issue 33, September 4, 2025.
Large‐scale generation of disc‐shaped models mimicking human epiblast layer is achieved by bioprinting of human pluripotent stem cells using a well‐defined biomatrix. The bioactive component and physical confinement from laminin/alginate microgels, combined with the endogenous regulation of the WNT signaling pathway regulated disc‐like morphogenesis ...
Yixue Luo, Liheng Luo, Ling Wang, Shanshan Yang, Hongan Ren, Shaojun Liang, Xiaoyu Wang, Yijun Su, Leqian Yu, Xiaoyue Wang, Mingen Xu, Rui Yao   +11 more
wiley   +1 more source

Conceptus signals for establishment and maintenance of pregnancy

Reproductive Biology and Endocrinology, 2004
Establishment and maintenance of pregnancy results from signaling by the conceptus (embryo/fetus and associated extraembryonic membranes) and requires progesterone produced by the corpus luteum (CL).
Bazer Fuller W, Spencer Thomas E
doaj   +1 more source

Reduced Offspring Viability Is Associated With Long‐Term Stability of a Narrow Avian Hybrid Zone

Ecology and Evolution, Volume 15, Issue 9, September 2025.
We investigated hybrid viability in a tropical, avian hybrid zone governed by strong selection on male secondary sexual traits between the white‐collared manakin (Manacus candei) and golden‐collared manakin (M. vitellinus). We assessed putative hybrid fitness by investigating adult survival and hatching success along with a prospective selective ...
Kira M. Long, Michael J. Braun, Adolfo Muñoz Abrego, Ovidio Jaramillo, Todd M. Jones, Jeffrey D. Brawn   +5 more
wiley   +1 more source

Polydactylous limbs in Strong's Luxoid mice result from ectopic polarizing activity [PDF]

, 1995
Strong's Luxoid (1st^D) is a semidominant mouse mutation in which heterozygotes show preaxial hindlimb polydactyly, and homozygotes show fore- and hindlimb polydactyly.
Chan, David C., Laufer, Ed, Leder, Philip, Tabin, Cliff   +3 more
core  

Integration of Bioengineered Tools in Assisted Reproductive Technologies

Advanced Healthcare Materials, Volume 14, Issue 21, August 19, 2025.
A conceptual illustration depicting the collaboration between a medical professional (right) and a scientist (left). Their connection highlights the integration of scientific research and clinical practice. This representation underscores the role of emerging technologies in bridging fundamental research with applied reproductive healthcare.
Aslı Ak, Edith Coonen, Ron van Golde, Erik Vrij   +3 more
wiley   +1 more source

Spatiotemporal Expression of Pregnancy-Specific Glycoprotein Gene rnCGMl in Rat Placenta [PDF]

, 1993
As a basis towards a better understanding of the role of the pregnancy-specific glycoprotein (PSG) family in the maintenance of pregnancy, detailed investigations are described on the expression of a recently identified rat PSG gene (rnCGM1) at the mRNA ...
Lucas, Kurt, Rebstock, Sabine, Thompson, John A., Weiss, Martina, Zimmermann, Wolfgang   +4 more
core   +1 more source

Development of node architecture and emergence of molecular organizer characteristics in the pig embryo

Developmental Dynamics, Volume 254, Issue 8, Page 916-934, August 2025.
Abstract Background The avian node is the equivalent of the amphibian Spemann's organizer, as indicated by its ability to induce a secondary axis, cellular contribution, and gene expression, whereas the node of the mouse, which displays limited inductive capacities, was suggested to be a part of spatially distributed signaling.
Braah Harmoush, Christoph Viebahn, Nikoloz Tsikolia   +2 more
wiley   +1 more source

A network of transient domains for breaking symmetry during anterior–posterior axis formation in the porcine embryo

Developmental Dynamics, Volume 254, Issue 8, Page 902-915, August 2025.
Abstract Breaking radial symmetry for anterior–posterior axis formation is one of the key developmental steps of vertebrate gastrulation and is established through a succession of transient domains defined by morphology or gene expression. Three such domains were interpreted recently in the rabbit to be part of a “three‐anchor‐point model” for axis ...
Ruben Plöger, Nikoloz Tsikolia, Christoph Viebahn   +2 more
wiley   +1 more source