Results 61 to 70 of about 8,634 (234)

Advances in non‐germ cell tumours of the testis: focus on new molecular developments in sex cord‐stromal tumours

open access: yesHistopathology, Volume 88, Issue 1, Page 230-251, January 2026.
In this review, we summarise the major recent advances in Testicular Sex Cord‐Stromal Tumours, focusing on molecular alterations and biomarkers relevant for diagnosis, classification and prognosis. Testicular sex cord‐stromal tumours (TSCSTs) represent ~4%–8% of all testicular neoplasms.
João Lobo, Andres M Acosta
wiley   +1 more source

Polydactylous limbs in Strong's Luxoid mice result from ectopic polarizing activity [PDF]

open access: yes, 1995
Strong's Luxoid (1st^D) is a semidominant mouse mutation in which heterozygotes show preaxial hindlimb polydactyly, and homozygotes show fore- and hindlimb polydactyly.
Chan, David C.   +3 more
core  

Germ cell and other tumors in individuals with differences in sex development

open access: yesCA: A Cancer Journal for Clinicians, Volume 75, Issue 6, Page 587-601, November/December 2025.
Abstract Approximately one in 3500 to one in 5100 live‐born infants have atypical external genital development, known as differences in sex development (DSD). In 2005, an expert consensus conference thoroughly reviewed aspects of health care for individuals with DSD.
Selma Feldman Witchel   +1 more
wiley   +1 more source

Dissecting the dynamics of signaling events in the BMP, WNT, and NODAL cascade during self-organized fate patterning in human gastruloids. [PDF]

open access: yes, 2019
During gastrulation, the pluripotent epiblast self-organizes into the 3 germ layers-endoderm, mesoderm and ectoderm, which eventually form the entire embryo.
Chhabra, Sapna   +4 more
core   +1 more source

Elevating Testosterone and Androstenedione Produces Temporary Sex‐Dependent Variation in Japanese Quail (Coturnix japonica) Embryonic Development

open access: yesJournal of Experimental Zoology Part A: Ecological and Integrative Physiology, Volume 343, Issue 9, Page 1103-1116, November 2025.
ABSTRACT Vertebrate growth rates may respond to maternally supplied steroids, yet injections of individual hormones into avian eggs of different species have produced inconsistent results. This might be because diverse steroids' concentrations are naturally correlated in yolks, injections are not elevating hormones at critical times in development, or ...
S. K. Winnicki   +4 more
wiley   +1 more source

Spatiotemporal segmentation of contraction waves in the extra-embryonic membranes of the red flour beetle

open access: yesBMC Bioinformatics
Background In this paper, we introduce an image analysis approach for spatiotemporal segmentation, quantification, and visualization of movement or contraction patterns in 2D+t and 3D+t microscopy recordings of biological tissues. The development of this
Marc Pereyra   +6 more
doaj   +1 more source

Conceptus signals for establishment and maintenance of pregnancy

open access: yesReproductive Biology and Endocrinology, 2004
Establishment and maintenance of pregnancy results from signaling by the conceptus (embryo/fetus and associated extraembryonic membranes) and requires progesterone produced by the corpus luteum (CL).
Bazer Fuller W, Spencer Thomas E
doaj   +1 more source

Expression of calcium transporting proteins by the extraembryonic membranes of squamate reptiles

open access: yesThe FASEB Journal, 2007
Eighty percent of squamate reptiles (snakes and lizards) lay eggs; however, over 100 species bear live young. The evolutionary transition from oviparity to viviparity involves loss of the eggshell, an important source of calcium for developing embryos.
Patricia Cross   +2 more
openaire   +1 more source

Human Endogenous Retroviruses and Diseases

open access: yesMedComm, Volume 6, Issue 11, November 2025.
Human endogenous retroviruses (HERVs), remnants of ancient retroviral integrations into the human genome, are modulated by viral infections, genetic inheritance, and triggers including environmental factors, epigenetic dysregulation, oncogene activation, and aging.
Can Chen   +9 more
wiley   +1 more source

Dad's Diet Shapes the Future: How Paternal Nutrition Impacts Placental Development and Childhood Metabolic Health

open access: yesMolecular Nutrition &Food Research, Volume 69, Issue 22, November 2025.
This review highlights the emerging connection between paternal nutrition‐induced sperm epigenetic changes and placental phenotypes that may influence offspring metabolic health. An accompanying interactive ShinyApp allows exploration of these sperm–placenta gene networks, a framework for future research seeking to explore candidate biomarkers or ...
David A. Skerrett‐Byrne   +6 more
wiley   +1 more source

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