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Regulatory mechanisms involved in pathoadaptation of extraintestinal pathogenic Escherichia coli

open access: yes, 2019
Establishment of commensal bacteria within a new niche of their host usually promotes the transition from commensalism to pathogenicity. Extraintestinal Pathogenic Escherichia coli (ExPEC) represent different pathovars with biphasic lifestyle – they can reside in the gut as commensals or they can escape and cause diseases elsewhere in the human body ...
openaire   +1 more source

Global Extraintestinal Pathogenic Escherichia coli (ExPEC) Lineages [PDF]

open access: yesClinical Microbiology Reviews, 2019
Extraintestinal pathogenic Escherichia coli (ExPEC) strains are responsible for a majority of human extraintestinal infections globally, resulting in enormous direct medical and social costs. ExPEC strains are comprised of many lineages, but only a subset is responsible for the vast majority of infections.
Amee R Manges, Johann D D Pitout
exaly   +3 more sources
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Extraintestinal pathogenic Escherichia coli : “The other bad E coli ”

Translational Research, 2002
Extraintestinal pathogenic Escherichia coli (ExPEC), the specialized strains of E coli that cause most extraintestinal E coli infections, represent a major but little-appreciated health threat. Although the reasons for their evolution remain mysterious, by virtue of their numerous virulence traits ExPEC clearly possess a unique ability to cause disease
James R Johnson, Thomas A Russo
exaly   +3 more sources

Pandemic lineages of extraintestinal pathogenic Escherichia coli [PDF]

open access: yesClinical Microbiology and Infection, 2014
Pathogenic Escherichia coli strains cause a wide variety of intestinal and extraintestinal infections. The widespread geographical clonal dissemination of intestinal pathogenic E. coli strains, such as E. coli O157:H7, is well recognized, and its spread is most often attributed to contaminated food products.
Lee W Riley
exaly   +3 more sources

What defines extraintestinal pathogenic Escherichia coli?

open access: yesInternational Journal of Medical Microbiology, 2011
Escherichia coli (E. coli) exhibits considerable physiological and metabolic versatility and includes a variety of non-pathogenic, commensal variants, which belong to the normal gut flora of humans and warm-blooded animals. Additionally, several pathogenic variants have been identified which cause various types of intestinal or extraintestinal ...
Ulrich Dobrindt
exaly   +3 more sources

Extraintestinal Pathogenic Escherichia coli

Foodborne Pathogens and Disease, 2007
Extraintestinal pathogenic Escherichia coli (ExPEC) possesses virulence traits that allow it to invade, colonize, and induce disease in bodily sites outside of the gastrointestinal tract. Human diseases caused by ExPEC include urinary tract infections, neonatal meningitis, sepsis, pneumonia, surgical site infections, as well as infections in other ...
James L, Smith   +2 more
openaire   +2 more sources

Extraintestinal Pathogenic Escherichia coli

2018
Extraintestinal pathogenic E. coli (ExPEC) present a major clinical problem that has emerged in the past years. Most of the infections are hospital or community-acquired and involve patients with a compromised immune system. The infective agents belong to a large number of strains of different serotypes that do not cross react.
Dvora, Biran, Eliora Z, Ron
openaire   +2 more sources

Molecular Epidemiology of Extraintestinal PathogenicEscherichia coli

EcoSal Plus, 2004
Extraintestinal pathogenicEscherichia coli(ExPEC), the specializedE. colistrains that possess the ability to overcome or subvert host defenses and cause extraintestinal disease, are important pathogens in humans and certain animals. Molecular epidemiological analysis has led to an appreciation of ExPEC as being distinct from otherE.
James R, Johnson, Thomas A, Russo
openaire   +3 more sources

Function of Rhs proteins in porcine extraintestinal pathogenic Escherichia coli PCN033

Journal of Microbiology, 2021
Extraintestinal pathogenic Escherichia coli (ExPEC) is an important zoonotic pathogen that places severe burdens on public health and animal husbandry. There are many pathogenic factors in E. coli. The type VI secretion system (T6SS) is a nano-microbial weapon that can assemble quickly and inject toxic effectors into recipient cells when danger is ...
Wenjia, Lu   +7 more
openaire   +2 more sources

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