Results 71 to 80 of about 5,282,350 (229)

NECTIN4 Expression in Extramammary Paget’s Disease: Implication of a New Therapeutic Target

International Journal of Molecular Sciences, 2020
Extramammary Paget’s disease (EMPD) is a rare skin cancer arising in the anogenital area. Most EMPD tumors remain dormant as in situ lesions, but the outcomes of patients with metastatic EMPD are poor because of the lack of effective systemic therapies ...
Maho Murata, Takamichi Ito, Yuka Tanaka, Y. Kaku-Ito, M. Furue   +4 more
semanticscholar   +1 more source

Nonmass‐Forming Type Anocanal Cancer With Pagetoid Spread With a Challenging Differential Diagnosis: A Case Report

Clinical Case Reports, Volume 14, Issue 5, May 2026.
ABSTRACT Pagetoid spread (PS) of anorectal cancer is relatively rare and is associated with poor prognosis compared with Extramammary Paget disease. It is therefore essential to accurately differentiate between the two entities. In PS cases, the primary tumor lesion is usually obvious; however, this is not the case in nonmass‐forming type anorectal ...
Mizunori Yaegashi, Ryo Sugimoto, Hiroaki Shimada, Akira Sasaki   +3 more
wiley   +1 more source

Advanced Extramammary Paget's Disease of the Groin, Penis, and Scrotum

, 2014
Extramammary Paget's disease (EMPD) is a rare intraepithelial malignancy arising in areas rich in apocrine glands, such as the perineum, vulva, axilla, scrotum, and penis.
Karlos Z. Oregel, Milikowski, Clara, Oregel, Karlos Z, Silva, Orlando, Gomez, Henry, Javier Cortes, Orlando Silva, Feun, Lynn, Isrow, Derek, Lynn Feun, Henry Gomez, Clara Milikowski, Cortes, Javier, Derek Isrow   +13 more
core   +1 more source

Frequent expression of the breast differentiation antigen NY-BR-1 in mammary and extramammary Paget's disease [PDF]

, 2010
While mammary Paget's disease (MPD) is clearly linked to breast cancer, the histogenesis of extramammary Paget's disease (EMPD) is controversial. Recently NY-BR-1, a differentiation antigen expressed in the breast and in skin adnexal structures was ...
Giger, O, Moch, H, Varga, Z, Alix O'Meara, Alexander Knuth, Caduff, R, O'Meara, A, Rosmarie Caduff, Dirk Jäger, Olivier Giger, Pierre-Andre Diener, Knuth, A, Diener, P A, Jäger, D, Zsuzsanna Varga, Holger Moch, Diener PA, Moch H, Giger O, Jäger D, Knuth A, Varga Z, O'Meara A, Caduff R   +23 more
core   +1 more source

Prostate carcinoma metastatic to the skin as an extrammamary Paget’s disease

Diagnostic Pathology, 2012
Aim The current paper describes a case of prostatic adenocarcinoma metastatic to the skin presenting as an extrammamary Paget's disease, a very rare and poorly characterised morphological entity. We report a case of prostatic carcinoma metastatic to skin
Petcu Eugen, Gonzalez-Serva Aldo, Wright Robert G, Slevin Mark, Brinzaniuc Klara   +4 more
doaj   +1 more source

Perianal Paget’s Disease in a Forty-Five-Year-Old Man and Review of the Literature [PDF]

Iranian Journal of Colorectal Research, 2015
Introduction Extramammary Paget’s disease is a rare neoplasm of the skin that might develop in perianal region. Although different management options are available, wide local excision is still the method of choice.
Yavar Shams Hojjati, Abbas Abdollahi, Ghodratollah Maddah, Asieh Sadat Fattahi   +3 more
doaj   +1 more source

Scrotal squamous cell carcinoma: Two HPV‐negative cases with probable UV‐ induced pathogenesis

JDDG: Journal der Deutschen Dermatologischen Gesellschaft, EarlyView.
Daniel Craus, Ulrike Wieland, Steffi Silling, Julia Hyun, Milan Vidakovic, Frank Oellig, Alexander Kreuter, Valentina Laura Müller   +7 more
wiley   +1 more source

A Multifaceted Holistic Review of the Literature on Scar Dermatoses

International Wound Journal, Volume 23, Issue 5, May 2026.
ABSTRACT Many cutaneous diseases originate or manifest in scars. Scars are areas of compromised skin, which renders them a vulnerable cutaneous district for diseases to develop. The pathophysiology explaining why some dermatoses grow in scars is not yet thoroughly explored. The present study reviews the present literature on scar dermatoses.
Dana Maria Khoury, Elias El Tayar, Edward Eid, Firas F. Haddad, Ossama Abbas, Mazen Kurban   +5 more
wiley   +1 more source

Vulvar Adenocarcinoma With Pagetoid Spread: A Case Report

Cancer Reports
Background In rare cases, cancer cells adjacent to the skin migrate intraepithelially and reach the epidermis, presenting a histological appearance similar to that of Paget's disease; this phenomenon is termed pagetoid spread. Herein, we report a case of
Kazuaki Nishimura, Seiji Kagami, Haruka Kajio, Tamaki Wada, Naoyuki Toki, Kiyoshi Yoshino   +5 more
doaj   +1 more source

Consensus on Human Epidermal Growth Factor Receptor 2 Overexpression Testing in Pan‐Tumor

Cancer Innovation, Volume 5, Issue 2, April 2026.
This is the first pan‐tumor human epidermal growth factor receptor 2 (HER2) testing consensus established by a national expert panel in China, addressing critical gaps in HER2 overexpression testing across solid tumors beyond breast and gastric cancers.
Zhe Wang, Lin Chen, Wei Rao, Baoshan Cao, Muyan Cai, Xiangshan Fan, Yuan Ji, Yuan Li, Yan Song, Yan Sun, Yu Sun, Chunyan Wu, Qingxin Xia, Yanfeng Xi, Liyan Xue, Rutie Yin, Han Liang, Jianming Ying   +17 more
wiley   +1 more source